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Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

Woman who does not feel pain

A woman has been identified by doctors to be able to withstand pain. Surgeons were surprised to encounter her when they noticed that she made a completely painless recovery after a surgery.

28 Mar 2019

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

The U.S. Food and Drug Administration today approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA.

28 Mar 2019

New strategy for potential treatment of HBV associated liver cancer

Researchers from Duke-NUS Medical School, Singapore General Hospital and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma, a commonly occurring liver cancer.

28 Mar 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

Artificial intelligence can predict risk of premature death

Artificial intelligence may significantly improve the accuracy of premature death prediction for patients with chronic disease, compared with standard models.

28 Mar 2019

Researchers describe mathematical model as key to developing effective drugs for brain disorders

A collaboration between researchers from the UAB Institute of Neurosciences and the pharmaceutical company GlaxoSmithKline, published in March in Trends in Pharmacological Sciences, describes a mathematical model to quantify the activity of biased G-protein-coupled receptors.

28 Mar 2019

Virtual reality could be used to treat people with neurological disorders

Playing games in virtual reality (VR) could be a key tool in treating people with neurological disorders such as autism, schizophrenia and Parkinson's disease.

28 Mar 2019

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted and immune-system-based therapies against the deadly brain tumor.

28 Mar 2019

Gene transfer technique can combat diabetes-linked heart dysfunction

Researchers with the VA San Diego Healthcare System and the University of California San Diego have shown that a gene transfer technique can combat heart dysfunction caused by diabetes.

28 Mar 2019

Study finds no damaging role for microglia during retinal prion disease in mice

National Institutes of Health scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice.

28 Mar 2019

Episodes of psychosis linked to air pollution

A new study on teenagers living in England and Wales has found that psychotic experiences are becoming increasingly common due to exposure to pollution.

28 Mar 2019

Portable mini microscope could improve scientists' ability to study brain disease in living mice

Working with mice, a team of Johns Hopkins Medicine researchers has developed a relatively inexpensive, portable mini microscope that could improve scientists' ability to image the effects of cancer, stroke, Alzheimer's disease and other conditions in the brains of living and active mice over time.

28 Mar 2019

Purdue engineers develop tiny glutamate sensors for spinal cord injuries

Your chances of getting a nasty migraine increase following a spinal cord injury, thanks to a chemical messenger in the brain that spikes to toxic levels, past studies have suggested.

28 Mar 2019

Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success.

28 Mar 2019

Radiolabeled protein lights up tumor to reveal where cancer drugs are working

Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography scans to calculate in real time how much of an immunotherapy drug reaches a tumor and what parts of a cancer remain unaffected.

28 Mar 2019

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Aging is a risk factor for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability.

28 Mar 2019

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

A pioneering clinical trial investigating medicinal cannabis as a potential treatment for people living with severe Tourette syndrome will be conducted by Wesley Medical Research, in Brisbane in Australia, with cannabis supply facilitated by Lambert Initiative for Cannabinoid Therapeutics at University of Sydney.

28 Mar 2019

Garvan researchers develop more accurate method to diagnose cancer subtypes

Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate snapshot of rearranged DNA found in cancer.

28 Mar 2019

Study describes new muscular disease caused by mutation in myoglobin gene

Researchers of the Bellvitge Biomedical Research Institute led by Dr. Montse Olivé have described in Nature Communications a new muscular disease caused by a mutation in the myoglobin gene.

28 Mar 2019

Medical Condition News

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Woman who does not feel pain

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

New strategy for potential treatment of HBV associated liver cancer

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Artificial intelligence can predict risk of premature death

Researchers describe mathematical model as key to developing effective drugs for brain disorders

Virtual reality could be used to treat people with neurological disorders

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

Gene transfer technique can combat diabetes-linked heart dysfunction

Study finds no damaging role for microglia during retinal prion disease in mice

Episodes of psychosis linked to air pollution

Portable mini microscope could improve scientists' ability to study brain disease in living mice

Purdue engineers develop tiny glutamate sensors for spinal cord injuries

Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

Radiolabeled protein lights up tumor to reveal where cancer drugs are working

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

Garvan researchers develop more accurate method to diagnose cancer subtypes

Study describes new muscular disease caused by mutation in myoglobin gene

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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