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Oral drug used to treat blood clots in cancer patients appears to be safe and effective

Mayo Clinic researchers have found that an oral drug, apixaban, used to treat blood clots in patients undergoing cancer therapy, is safe and effective.

4 Dec 2018

Engineers develop non-invasive method for detecting bladder cancer

A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

Personalized scans showing the extent of atherosclerosis help decrease cardiovascular risk

A new randomized trial of over 3000 people in The Lancet finds that sharing pictorial representations of personalized scans showing the extent of atherosclerosis (vascular age and plaque in the arteries) to patients and their doctors results in a decreased risk of cardiovascular disease one year later, compared to people receiving usual information about their risk.

4 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.

3 Dec 2018

One-quarter of patients with diabetes report using less insulin due to high costs

For patients with diabetes, insulin is a life-saving medicine and an essential component of diabetes management, yet in the past decade alone, the out-of-pocket costs for insulin have doubled in the United States.

3 Dec 2018

New drug combination could kill melanoma cells more effectively, study shows

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

3 Dec 2018

Study examines whether taking multiple medications for heart failure can limit abilities in older adults

As we age, we tend to develop a number of chronic health conditions and concerns. Often, managing health problems can mean that older adults may take many different medications. When older adults take five or more medicines (a scenario health experts call "polypharmacy", it can increase the risk of harmful side effects.

3 Dec 2018

Hoosier firefighters have greater risk of dying from cancer than non-firefighters

Hoosier firefighters face a significantly higher risk of dying from cancer than non-firefighters in Indiana, according to a study that shows death from malignant cancers was the leading cause of death for Indiana firefighters between 1985 and 2013.

3 Dec 2018

Alcohol consumption may attenuate long-term weight loss in people with Type 2 diabetes

Research shows that losing weight can help prevent or delay the onset of diabetes. While best practice for weight loss often includes decreasing or eliminating calories from alcohol, few studies examine whether people who undergo weight loss treatment report changes in alcohol intake and whether alcohol influences their weight loss.

3 Dec 2018

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

Chimeric antigen receptor T-cell therapy, or CAR T, was named the 2017 Advance of the Year by the American Society of Clinical Oncology. The FDA approved two CAR T products last year for treatment of adult large B-cell lymphoma based on the exceptional patient outcomes seen in clinical trials.

3 Dec 2018

UK scientists find new way to identify patients with aggressive lymphoma

UK scientists have found a new way to identify people with the most aggressive types of lymphoma who are less likely to respond to standard drugs.

3 Dec 2018

Very low calorie diet for type 2 diabetes to be prescribed

General Practitioners in England would soon prescribe a very low calorie diet (VLCD) for patients with type 2 diabetes in England as part of an attempt to reverse the increasingly growing numbers of the disease.

3 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Tailored lifestyle recommendations during colorectal cancer screening promote healthy behaviors

A program that provided individually tailored lifestyle recommendations for patients undergoing screening for colorectal cancer helped encourage healthy behavior, according to results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

3 Dec 2018

Researchers uncover genes that lead to excessive tau in dementia

Researchers have identified two major groups of genes involved in the mutations that lead to excess production of tau, a protein involved in dementia.

3 Dec 2018

Full marathons may increase concentrations of biomarkers of cardiac strain

Full marathons may significantly raise concentrations of several biomarkers of strain on the heart, according to new research in Circulation, Journal of the American Heart Association.

3 Dec 2018

Study: 51% of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma

A follow-up analysis of patients enrolled in a Phase I/II multi-center trial for diffuse large B-cell lymphoma reported 51 percent of patients receiving an anti-CD19 chimeric antigen receptor (CAR T) called axi-cel were still alive two years post-treatment.

3 Dec 2018

Cleveland Clinic expert develops personalized prediction model for Myelodysplastic Syndromes

At the American Society of Hematology Annual Meeting, Cleveland Clinic medical hematologist and oncologist Aziz Nazha, M.D., will present results of a personalized prediction model that surpassed current prediction models for Myelodysplastic Syndromes.

3 Dec 2018

Medical Condition News

Oral drug used to treat blood clots in cancer patients appears to be safe and effective

Engineers develop non-invasive method for detecting bladder cancer

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

Personalized scans showing the extent of atherosclerosis help decrease cardiovascular risk

New strategies may improve performance of CAR-T cell therapy in treating cancer

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

One-quarter of patients with diabetes report using less insulin due to high costs

New drug combination could kill melanoma cells more effectively, study shows

Study examines whether taking multiple medications for heart failure can limit abilities in older adults

Hoosier firefighters have greater risk of dying from cancer than non-firefighters

Alcohol consumption may attenuate long-term weight loss in people with Type 2 diabetes

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

UK scientists find new way to identify patients with aggressive lymphoma

Very low calorie diet for type 2 diabetes to be prescribed

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Tailored lifestyle recommendations during colorectal cancer screening promote healthy behaviors

Researchers uncover genes that lead to excessive tau in dementia

Full marathons may increase concentrations of biomarkers of cardiac strain

Study: 51% of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma

Cleveland Clinic expert develops personalized prediction model for Myelodysplastic Syndromes

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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