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New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

HealthCore, Inc., the outcomes research subsidiary of Anthem, Inc. and Novo Nordisk Inc., which manufacturers the once weekly GLP-1 receptor agonist Ozempic (semaglutide), are working together to launch the first of its kind pragmatic study to understand the benefits of semaglutide as compared with all other available diabetes drugs in a real-world pragmatic clinical trial for Type 2 diabetes - one of the nation's fastest growing chronic diseases.

17 Oct 2018

Patients once thought incurable can benefit from high-dose radiation therapy

In the first randomized, phase II clinical trial of its kind, researchers have shown that an aggressive form of high-precision radiation therapy can greatly increase how long oligometastatic patients live and doubles how long they live without cancer.

17 Oct 2018

FDA grants Rare Pediatric Disease Designation for Immusoft’s Iduronicrin genleukocel-T

Immusoft Corporation, a Seattle-Wash.-based cell therapy company, announced today that the U.S. Food and Drug Administration (FDA) has granted it Rare Pediatric Disease Designation (RPDD) for Iduronicrin genleukocel-T, Immusoft's Sleeping Beauty transposon-engineered autologous plasmablasts for the expression and delivery of alpha-L-iduronidase (IDUA) to treat Mucopolysaccharidosis type I (MPS I).

17 Oct 2018

Research shows people over 65 are not performing enough physical activity

A research led by the University of Jaén reveals that people over 65 are not performing enough physical activity. Experts emphasize the importance of preserving physical performance to prevent the negative consequences of aging.

17 Oct 2018

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Lack of sleep during adolescence and early adulthood accelerates Alzheimer’s disease-related tau pathology, finds a study of male and female mice published in JNeurosci.

17 Oct 2018

Novel method uses just a drop of blood to monitor effect of lung cancer therapy

Dr Tasuku Honjo won the 2018 Nobel Prize in physiology or medicine for discovering the immune T-cell protein PD-1. This discovery led to a set of anti-cancer medications called checkpoint inhibitors, one of the first of which was nivolumab (Opdivo).

17 Oct 2018

Preoperative weight loss may not provide health benefits after surgery

For obese and overweight patients, it is common for various surgical procedures to be deferred until they have lost weight through diet and exercise.

17 Oct 2018

Study reveals link between childhood abuse and higher arthritis risk in adulthood

In a survey-based study of 21,889 adults in Canada, severe and/or frequent physical abuse during childhood and frequent childhood exposure to intimate partner violence were linked with higher risks or arthritis during adulthood arthritis, even after controlling for a range of factors. The findings are published in Arthritis Care & Research.

17 Oct 2018

New blood test could spare cancer patients from unnecessary chemotherapy

Cancer patients could be spared unnecessary chemotherapy - and its side effects - by a new blood test that is in clinical trials at more than 40 hospitals in Australia and New Zealand.

17 Oct 2018

Patients with hypertension and psoriasis more often require cardiovascular interventions

Psoriasis is linked with increased risks of hypertension and cardiovascular disease, but its effect on the course of cardiovascular disease remains unknown.

17 Oct 2018

Antidepressant treatment may lead to improvements in sleep quality of patients with depression

In a study of 15 patients affected by major depressive disorder and complaining of insomnia, initiating treatment with vortioxetine for their depressive symptoms led to significant improvements in subjective sleep quality and daytime sleepiness.

17 Oct 2018

Researchers to develop new stem cell-based strategies for treating vision disorders

A team from the University of Pennsylvania, Children's Hospital of Philadelphia, and University of Wisconsin--Madison are launching a project to develop new strategies for treating vision disorders using cells implanted in the retina.

17 Oct 2018

Research aims to address health disparities in African-American men

The burden of risk factors for chronic disease is substantially higher in black men compared with their white counterparts, including a higher prevalence of obesity and hypertension.

17 Oct 2018

Researchers discover why heart contractions are weaker in individuals with HCM

When a young athlete suddenly dies of a heart attack, chances are high that they suffer from familial hypertrophic cardiomyopathy. Itis the most common genetic heart disease in the US and affects an estimated 1 in 500 people around the world.

17 Oct 2018

Purdue Pharma, Eisai announce positive topline results from Phase 3 study of lemborexant

Eisai Co., Ltd. and Purdue Pharma L.P. announced positive topline results from SUNRISE 2, a long-term Phase 3 efficacy and safety evaluation of lemborexant, an investigational agent for sleep-wake regulation currently being studied for the potential treatment of multiple sleep-wake disorders.

17 Oct 2018

Down syndrome may hold important clues to onset of Alzheimer's disease

At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21.

17 Oct 2018

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

A recent article by a team of international experts on multiple sclerosis (MS) underscores the importance of expanding the knowledge base about the hippocampus in order to better understand the genesis of cognitive deficits and develop new treatment strategies.

17 Oct 2018

Researchers find opportunity to control salt-sensitive hypertension without exercising

Couch potatoes rejoice -- there might be a way to get the blood pressure lowering benefits of exercise in pill form.

16 Oct 2018

Environmental conditions may drive development of multiple sclerosis

A new Tel Aviv University study finds that certain environmental conditions may precipitate structural changes that take place in myelin sheaths in the onset of multiple sclerosis. Myelin sheaths are the "insulating tape" surrounding axons; axons carry electrical impulses in neurons.

16 Oct 2018

New research identifies modifiable dementia risk factor in elderly people

For older adults, it may seem as though the die is already cast regarding their odds of developing dementia, but new research from the University of Pittsburgh has identified a dementia risk factor among older adults that should be modifiable even well into old age.

16 Oct 2018

Medical Condition News

New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

Patients once thought incurable can benefit from high-dose radiation therapy

FDA grants Rare Pediatric Disease Designation for Immusoft’s Iduronicrin genleukocel-T

Research shows people over 65 are not performing enough physical activity

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Novel method uses just a drop of blood to monitor effect of lung cancer therapy

Preoperative weight loss may not provide health benefits after surgery

Study reveals link between childhood abuse and higher arthritis risk in adulthood

New blood test could spare cancer patients from unnecessary chemotherapy

Patients with hypertension and psoriasis more often require cardiovascular interventions

Antidepressant treatment may lead to improvements in sleep quality of patients with depression

Researchers to develop new stem cell-based strategies for treating vision disorders

Research aims to address health disparities in African-American men

Researchers discover why heart contractions are weaker in individuals with HCM

Purdue Pharma, Eisai announce positive topline results from Phase 3 study of lemborexant

Down syndrome may hold important clues to onset of Alzheimer's disease

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

Researchers find opportunity to control salt-sensitive hypertension without exercising

Environmental conditions may drive development of multiple sclerosis

New research identifies modifiable dementia risk factor in elderly people

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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