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FLX Bio treats first patient in its Phase 1/2 clinical trial of FLX475 for treating various advanced cancers

FLX Bio, Inc., a clinical-stage, biopharmaceutical company focused on the development of oral small-molecule drugs that target drivers of cancer and other immune-related disorders, today announced that the first patient has been treated in its Phase 1/2 clinical trial of FLX475 in patients with various advanced cancers. FLX475 is an oral, small molecule CCR4 antagonist that selectively inhibits migration of regulatory T cells into the tumor microenvironment.

27 Sep 2018

CytoSen receives favorable response from FDA to its pre-IND meeting package for CSTD002-NK

CytoSen Therapeutics, a private biopharmaceutical company accelerating innovation in Natural Killer cell therapy, today announced it has received a favorable response from the U.S. Food and Drug Administration to its pre-Investigational New Drug meeting package for the proposed Phase 2 trial of CytoSen's adoptive NK cell therapy, CSTD002-NK, for the reduction of relapse in high risk acute myeloid leukemia or myelodysplastic syndrome in patients undergoing haploidentical hematopoietic stem cell transplantation.

27 Sep 2018

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today positive topline results from the interim analysis of the ENVISION Phase 3 Study of givosiran, an investigational RNAi therapeutic targeting aminolevulinic acid synthase 1 for the treatment of acute hepatic porphyria.

27 Sep 2018

Decibel obtains exclusive license to commercialize ORC-13661 for preventing hearing, balance disorders

Decibel Therapeutics and Oricula Therapeutics today announced that Decibel has obtained an exclusive, worldwide license to the development and commercialization of ORC-13661, an oral medication developed by Oricula Therapeutics for the prevention of hearing loss and balance disorders that can occur following treatment of severe infections with aminoglycoside antibiotics.

27 Sep 2018

Updated model of PAXMAN Scalp Cooling System launched

British scalp cooling expert, PAXMAN have launched the latest model of the PAXMAN Scalp Cooling System. Following successful launch in the US this updated model is being rolled out to the UK and rest of world markets.

From Paxman 27 Sep 2018

OrthoSera presents first-in-man study results of hyperacute serum in knee osteoarthritis

OrthoSera GmbH, an orthobiologics company developing serum-based solutions for musculoskeletal indications announces results of its first-in-man pilot clinical study of hyperacute serum on 36 patients in knee osteoarthritis.

27 Sep 2018

Novel therapy technique double rate of upper limb recovery in stroke patients

A novel therapy technique invented by researchers at The University of Texas at Dallas has been shown in a pilot study to double the rate of upper limb recovery in stroke patients, a leap forward in treating the nearly 800,000 Americans who suffer strokes each year.

27 Sep 2018

EU conducts research into mechanisms and effects of atrial fibrillation

Atrial fibrillation is the most common type of irregular heartbeat, or cardiac arrhythmia, affecting 2-3 % of the European population and as many as one in 10 people over the age of 80.

27 Sep 2018

Researchers develop new tool to screen for sleep apnea in people with epilepsy

Rutgers researchers have developed a tool to help neurologists screen for obstructive sleep apnea in people with epilepsy whose seizures can be magnified by sleep disorders.

27 Sep 2018

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Approximately 1.25 million Americans are living with type 1 diabetes, with an additional 40,000 people newly diagnosed every year.

27 Sep 2018

UC Riverside researchers receive NIH grant to study alcohol use disorders among Pacific Islanders

Pacific Islanders, who trace their roots to the native peoples of Hawaii, Guam, Samoa, and other Pacific Islands, make up the third-fastest-growing racial group in the United States.

27 Sep 2018

Auto-FMT found to be safe, effective way to replenish beneficial gut bacteria in cancer patients

Researchers at Memorial Sloan Kettering Cancer Center have shown that autologous fecal microbiota transplantation (auto-FMT) is a safe and effective way to help replenish beneficial gut bacteria in cancer patients who require intense antibiotics during allogenic hematopoietic stem cell transplantation.

27 Sep 2018

VCU researchers to study how a gene could influence cognitive decline during chemotherapy

With the help of a $2.1 million grant, Virginia Commonwealth University School of Nursing researchers will study how a gene that regulates estrogen and neurotransmitter levels could be tied to cognitive decline in patients undergoing chemotherapy for breast and endometrial cancers.

27 Sep 2018

Antibiotic resistance in cystic fibrosis linked to decreased microbial diversity and pulmonary function

A defective gene causes thick, sticky mucus to build up in the lungs of patients with cystic fibrosis. There, it traps bacteria, causing patients to develop frequent lung infections that progressively damage these vital organs and impair patients' ability to breathe.

27 Sep 2018

Rutgers study uncovers new mechanism linked to Alzheimer's and traumatic brain injury

Rutgers researchers have discovered a new mechanism that may contribute to Alzheimer's disease and traumatic brain injury. They now hope to launch a clinical trial to test the treatment in humans.

27 Sep 2018

New drug to treat Parkinson's disease psychosis do not pose greater risk of death

In the wake of media and public reports about increased mortality linked to a new drug for treating Parkinson's disease psychosis -- a symptom of the progressive nervous system disorder in which patients experience hallucinations and delusions -- researchers at University of California San Diego School of Medicine conducted a retrospective study of qualifying patients in the UC San Diego Health system, concluding that the new drug, pimavanserin, did not pose a statistically significant greater risk of death.

27 Sep 2018

Olfactory cells could act as 'Trojan horse,' delivering anticancer therapy to dangerous brain tumors

A special type of cell essential to the ability of olfactory neurons to regenerate may be genetically engineered to deliver anticancer therapy to the dangerous brain tumors called glioblastomas.

27 Sep 2018

UH pharmacologist receives NIH grant to improve kidney function in older people

Mohammad Asghar, associate professor of pharmacology at the University of Houston, has been awarded $459,000 from the National Institutes of Health/National Institute on Aging to improve kidney function in people 65 and older, a population at higher risk for developing impaired kidney function.

27 Sep 2018

Moffitt researcher awarded World Molecular Imaging Society's highest honor

Robert Gillies, Ph.D., chair of the Department of Cancer Physiology and vice chair of Radiology Research at Moffitt Cancer Center, was awarded the World Molecular Imaging Society's highest honor.

27 Sep 2018

Sudden cardiac death linked to mitral valve prolapse in large Australian study

A latest study has shown that sudden cardiac death could be linked to a very common heart condition – mitral valve prolapse. Sudden cardiac death occurs when the heart suddenly stops beating. This connection is a significant breakthrough say experts.

26 Sep 2018

Medical Condition News

FLX Bio treats first patient in its Phase 1/2 clinical trial of FLX475 for treating various advanced cancers

CytoSen receives favorable response from FDA to its pre-IND meeting package for CSTD002-NK

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Decibel obtains exclusive license to commercialize ORC-13661 for preventing hearing, balance disorders

Updated model of PAXMAN Scalp Cooling System launched

OrthoSera presents first-in-man study results of hyperacute serum in knee osteoarthritis

Novel therapy technique double rate of upper limb recovery in stroke patients

EU conducts research into mechanisms and effects of atrial fibrillation

Researchers develop new tool to screen for sleep apnea in people with epilepsy

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

UC Riverside researchers receive NIH grant to study alcohol use disorders among Pacific Islanders

Auto-FMT found to be safe, effective way to replenish beneficial gut bacteria in cancer patients

VCU researchers to study how a gene could influence cognitive decline during chemotherapy

Antibiotic resistance in cystic fibrosis linked to decreased microbial diversity and pulmonary function

Rutgers study uncovers new mechanism linked to Alzheimer's and traumatic brain injury

New drug to treat Parkinson's disease psychosis do not pose greater risk of death

Olfactory cells could act as 'Trojan horse,' delivering anticancer therapy to dangerous brain tumors

UH pharmacologist receives NIH grant to improve kidney function in older people

Moffitt researcher awarded World Molecular Imaging Society's highest honor

Sudden cardiac death linked to mitral valve prolapse in large Australian study

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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