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Therapeutic implications of caffeine in neuropsychiatric disorders

An important new article reviews recently discovered properties of adenosine A2A receptor-dopamine D2 receptor and adenosine A1 receptor-dopamine D1 receptor heteromers--both of which are main targets for caffeine--and discusses the therapeutic implications of these findings.

7 Jan 2019

UC researchers receive $3.2 million grant to study stroke recurrence risk

Researchers at the University of Cincinnati have received a $3.2 million grant from the National Institute of Neurological Diseases to study the use of neuroimaging to pinpoint the risk factors of stroke recurrence.

7 Jan 2019

First patient enrolled in pancreatic cancer clinical trial

The Henry Ford Cancer Institute announced today it has enrolled the first patient in a new clinical trial to test the effectiveness of using precise, higher dose MRI-guided radiation therapy to treat pancreatic cancer.

7 Jan 2019

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance - a new study at Karolinska Institutet reveals.

7 Jan 2019

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

Johns Hopkins researchers have identified a protein involved in cell proliferation and the development of new blood vessels that could serve as a marker for the early detection of colorectal cancers.

7 Jan 2019

First viable mouse model of Hirschsprung's disease developed

About one in every 5,000 babies is born without enteric neurons in distal colon resulting in Hirschsprung's disease. Because of the lacking neurons, contents of the gut cannot pass normally resulting in constipation and enlargement of colon.

7 Jan 2019

Study confirms increased pneumonia risk with prescription opioids

A study led by researchers at Yale University has shown that taking prescribed opioids increases the risk of pneumonia, irrespective of HIV status.

7 Jan 2019

Alzheimer's pathophysiology shows racial disparities

A study has identified racial disparities between African-Americans and Caucasians in the way in which Alzheimer’s disease arises and develops.

7 Jan 2019

Genes are involved in development of atrial fibrillation

Atrial fibrillation is the most common form of heart arrhythmia. About ten per cent of everyone over age 75 develop this condition, in which the two upper chambers of the heart (the atria) beat much faster than the main chambers (the ventricles), creating a fluttering feeling in the chest.

7 Jan 2019

Income volatility may be linked with increased risk of developing heart disease

Sudden, unpredictable drops in personal income during young adulthood are associated with an increased risk of developing heart disease and/or dying from any cause, according to new research in the American Heart Association's journal Circulation.

7 Jan 2019

Northwestern Medicine receives $10 million gift to create new institute for urologic cancers

Northwestern Medicine received a $10 million gift to fund the creation of a new multidisciplinary institute dedicated to urologic cancers.

7 Jan 2019

Study finds increase in suicide risk after cancer diagnosis

New research indicates that the risk of suicide increases significantly in the first year following a diagnosis of cancer, and this increase varies by the type of cancer diagnosed.

7 Jan 2019

Discovery may lead to new form of treatment for diabetes

Diabetes is caused by damaged or non-existing insulin cells inability to produce insulin, a hormone that is necessary in regulating blood sugar levels. Many diabetes patients take insulin supplements to regulate these levels.

7 Jan 2019

Exploring the prevalence of food allergies among U.S. adults

Survey data suggest at least 1 in 10 U.S. adults are food allergic and nearly 1 in 5 believe they have a food allergy. Food allergies are expensive and potentially life-threatening conditions.

7 Jan 2019

Cardiac events, stroke result in unemployment, lower income among survivors of working age

People who have experienced a heart attack (myocardial infarction), stroke or cardiac arrest are significantly less likely to be working than healthy people, and if they are working, on average have lower incomes, found a study published in CMAJ.

7 Jan 2019

GE Healthcare and VUMC announce partnership to enable safer, more precise cancer immunotherapies

GE Healthcare and Vanderbilt University Medical Center today announced a five-year partnership to enable safer and more precise cancer immunotherapies. Multiple diagnostic tools will be developed to help predict both the efficacy of an immunotherapy treatment and its adverse effects for a specific patient before the therapy is administered.

7 Jan 2019

Link between glycemic control and family support among Nigerians with type 2 diabetes mellitus

In the current issue of Family Medicine and Community Health (Volume 6, Number 4, 2018; DOI: https://doi.org/10.15212/FMCH.2018.0115, Nnenna A. Osuji, Oluwaseun Solomon Ojo, Sunday O. Malomo, Peter T. Sogunle, Ademola O. Egunjobi and Olufisayo O. Odebunmi of the Family Medicine Department, Federal Medical Centre, Abeokuta, Nigeria describe how Nigeria and other sub-Saharan African countries are currently experiencing a rapid increase in the incidence of noncommunicable diseases, especially diabetes mellitus (DM), as a result of increasing urbanization and changing lifestyles.

7 Jan 2019