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Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

HPV discovery could lead to new treatments for cervical cancer

Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus that could lead to new treatments for cervical cancer and other cancers caused by the virus.

19 Dec 2018

Real-time neurofeedback controls Parkinson’s brainwaves

A neurofeedback system enables Parkinson’s disease patients to voluntarily control brainwaves associated with symptoms of the disorder, according to new research published in eNeuro. It remains to be determined whether such a system can provide symptom relief.

From Society for Neuroscience 19 Dec 2018

Women who had low birthweight face increased risk of pregnancy complications

Women who were born with a low birthweight are at increased risk of pregnancy complications, according to a new Obesity study.

19 Dec 2018

Study finds elevated lung cancer risk after lung transplantation

In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients.

19 Dec 2018

Pregnant women and extremely obese people at high risk of flu complications

Pregnant women and the extremely obese are among those at high risk for complications from the flu - including death - and should be tested and begin antiviral treatment promptly if they are sick enough to be hospitalized with flu symptoms, according to updated guidelines released by the Infectious Diseases Society of America.

19 Dec 2018

Food insecurity associated with increased odds of binge-eating disorder and obesity

Food insecurity--difficulty affording enough food to support regular, balanced meals--was associated with increased likelihoods of binge-eating disorder and obesity in a recent International Journal of Eating Disorders study.

19 Dec 2018

Researchers aim to improve cognition, reverse weight gain in schizophrenia

Aerobic exercise can improve the size and function of the brain, and now investigators want to know if it can also improve cognitive function in patients with schizophrenia who struggle with memory and attention problems.

19 Dec 2018

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Chronic fatigue syndrome connected with an overactive immune system

A new study has shown that overactive immune systems may be the trigger that gives rise to chronic fatigue syndrome (CFS). The study results were published in the latest issue of the journal Psychoneuroendocrinology.

19 Dec 2018

Study may identify new diagnostics and treatment option for CVD

Forty-two percent of all deaths in the United States are related to cardiovascular disease. According to the Global Cardiovascular Drugs Market Forecast, by 2030 the number of deaths from CVD will rise to 23.6 million per year in the U.S. alone.

19 Dec 2018

FDA supports C-Path's Type 1 Diabetes Consortium to pursue biomarker qualification

Critical Path Institute (C-Path) announced today that its Type 1 Diabetes (T1D) Consortium has received a positive response to its Letter of Intent (LOI) from the U.S. Food and Drug Administration (FDA) detailing the FDA's decision to accept the consortium's Biomarker Initiative project into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program (BQP).

19 Dec 2018

Looking outside the tumor and thinking outside the box to diagnose lung cancer

Scientists in Anant Madabhushi's computational imaging lab at Case Western Reserve University have started thinking outside the box--or in their case, looking outside the tumor.

19 Dec 2018

Split liver transplants could save children on wait list finds study

A review analysed 5,300 cases of liver transplants on children across the country. The team of researchers from the Johns Hopkins Medicine looked at the patients who were more likely to survive after a split liver transplant. A split liver transplant is a type of transplant where the recipient receives only a part of the donor’s liver.

18 Dec 2018

UC San Diego Health offers new DRG stimulation device for phantom limb pain

In May 2000, Raul Silva was involved in a motorcycle accident in Baja California, Mexico, badly breaking his left femur, or thighbone. He underwent emergency surgery in Mexicali and, at first, everything seemed fine. Then an infection set in, worsened, and Silva eventually made his way to San Diego, where his left leg was amputated.

18 Dec 2018

Mindfulness training could be excellent strategy to prevent and manage obesity

Mindfulness training may improve the effectiveness of intensive weight management programs, suggesting that it could be an excellent strategy for healthcare providers in preventing and managing obesity.

18 Dec 2018

New drug could significantly slow progression of ALS, shows research

A new drug could significantly slow the progression of ALS, also known as Lou Gehrig's disease, according to new research by University of Alberta biologists. Current treatments slow progression of the degenerative disease by only a few months, and these findings could revolutionize the treatment of patients suffering from ALS, extending and improving quality of life.

18 Dec 2018

Weight change in middle-aged, elderly Chinese Singaporeans related to increased risk of death

Both moderate-to-large weight gain and weight loss, defined as a change of 10% or more in weight, among middle-aged and elderly Chinese Singaporeans are linked to increased risk of death, particularly from cardiovascular disease, and between them, weight loss was associated with higher risk than weight gain.

18 Dec 2018

Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice

Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.

18 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018