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Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Pfizer Inc. and Eli Lilly and Company today announced that a 16-week Phase 3 study in patients with osteoarthritis pain evaluating subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, met all three co-primary endpoints.

19 Jul 2018

WFN to highlight clean air for brain health on World Brain Day 2018

Global air pollution is not a problem that only affects lung health. Recent data show that airborne pollutants account for 30 percent of acute stroke cases worldwide.

19 Jul 2018

Study uncovers new protein complex that shields broken DNA ends

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.

19 Jul 2018

Gene regulator associated with protein pileup in exfoliation glaucoma

In exfoliation glaucoma, a protein dandruff clogs the outflow pathway for the fluid in our eyes.

19 Jul 2018

Analysis reveals disparities in cancer death rates among minority groups

Analysis of cancer death data from 2008-2014 in New York state revealed high cancer mortality rates among U.S.-born blacks and Puerto Ricans and relatively low cancer mortality rates among Hispanic South Americans and Asians.

19 Jul 2018

Bundled-payment system did not lower costs for serious medical conditions, shows study

A payment system that provides financial incentives for hospitals that reduce health-care costs for Medicare patients did not lower costs as intended, according to a new study led by Washington University School of Medicine in St. Louis.

19 Jul 2018

Researchers unravel how ALL invades the central nervous system

A deadly feature of acute lymphoblastic leukemia is its invasion of the central nervous system.

19 Jul 2018

Study finds link between DNA methylation and non-alcoholic fatty liver disease

DNA methylation is a molecular process that helps enable our bodies to repair themselves, fight infection, get rid of environmental toxins, and even to think. But sometimes this process goes awry.

19 Jul 2018

UA researchers to repurpose ketamine to reduce side effects in Parkinson's patients

The best-known treatment for Parkinson's disease isn't perfect. Named levodopa, the drug can treat the stiffness and slowness of movement associated with the debilitating disease.

19 Jul 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

Researchers gain more insight into how FUS protein causes ALS and FTLD

The mutated and aggregated protein FUS is implicated in two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

19 Jul 2018

New machine-learning model shows promise in predicting undiagnosed dementia

Improving dementia care through increased and timely diagnosis in the UK is a priority for the National Health Service, yet around half of those living with dementia live with the condition unaware.

19 Jul 2018

Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay – sometimes even after treatment has concluded.

19 Jul 2018

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Scientists at Dana-Farber/Brigham and Women's Cancer Center have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

19 Jul 2018

Alcohol-related cirrhosis mortality on the rise among young adults

Deaths from cirrhosis rose in all but one state between 1999-2016, with increases seen most often among young adults, a new study shows.

19 Jul 2018

Researchers identify new compound that protects against neurodegeneration

Researchers from the University of Liverpool have identified a new compound that protects against neurodegeneration in nematode worms. The discovery may enable novel treatments for human neurodegenerative diseases to be developed in the future.

18 Jul 2018

High bitter-taste sensitivity linked to increased risk of cancer

High bitter-taste sensitivity is associated with a significantly increased risk of cancer in older British women, according to researchers who conducted a unique study of 5,500 women whose diet, lifestyle and health has been tracked for about 20 years.

18 Jul 2018

Medical Condition News

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

WFN to highlight clean air for brain health on World Brain Day 2018

Study uncovers new protein complex that shields broken DNA ends

Gene regulator associated with protein pileup in exfoliation glaucoma

Analysis reveals disparities in cancer death rates among minority groups

Bundled-payment system did not lower costs for serious medical conditions, shows study

Researchers unravel how ALL invades the central nervous system

Study finds link between DNA methylation and non-alcoholic fatty liver disease

UA researchers to repurpose ketamine to reduce side effects in Parkinson's patients

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

Researchers gain more insight into how FUS protein causes ALS and FTLD

New machine-learning model shows promise in predicting undiagnosed dementia

Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Alcohol-related cirrhosis mortality on the rise among young adults

Researchers identify new compound that protects against neurodegeneration

High bitter-taste sensitivity linked to increased risk of cancer

Digital media use raising risk of ADHD symptoms among the young

Study: People with HIV twice as likely to suffer from heart disease

Study finds discharge against medical advice as predictor of readmissions in heart attack patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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