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Interaction between dioxin and HLA gene variant activates events associated with rheumatoid arthritis

It has been known for more than three decades that individuals with a particular version of a gene - human leukocyte antigen (HLA) - have an increased risk for rheumatoid arthritis.

19 Apr 2018

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression.

19 Apr 2018

Study shows testosterone deficiency in men is associated with chronic diseases

A male's total testosterone level may be linked to more than just sexual health and muscle mass preservation, a new study finds. Low amounts of the hormone could also be associated with chronic disease, even among men 40 years of age and younger.

19 Apr 2018

Environmental pollutants found to worsen rheumatoid arthritis

Scientists have uncovered a link between the risk of developing rheumatoid arthritis and environmental pollutants, such as cigarette smoke.

19 Apr 2018

Study highlights need for further evidence to improve symptom management in end of life care

A study looking at the personal perceptions and experiences of patients, families and healthcare professionals, has highlighted the need for improvement in symptom management in end of life care.

19 Apr 2018

Finding the 'keyhole' to beat obesity at the cellular level

An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger.

19 Apr 2018

Case study shows how intravascular ultrasound imaging helps detect acute aortic syndrome

In the current issue of Cardiovascular Innovations and Applications (Volume 2, Number 4, 2018, pp 447-449(3); DOI: https://doi.org/10.15212/CVIA.2017.0028, Niya Mileva, Medical University of Sofia, Sofia, Bulgaria and other researchers from Poland and Italy present a case study of misdiagnosed aortic intramural hematoma and the role of intravascular ultrasound imaging in detection of acute aortic syndrome.

19 Apr 2018

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient signal-to-noise ratios.

19 Apr 2018

Genome editing identifies neural circuit behind leptin’s anti-obesity and anti-diabetes effects

Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine have used CRISPR genome editing to identify a neural circuit in the hypothalamus as the primary mechanism in mediating leptin's anti-obesity and anti-diabetes effects and have identified two distinct mechanisms underlying leptin's inhibition of appetite.

19 Apr 2018

The Swedish Childhood Cancer Foundation awards grant to KI researchers

Ten researchers at Karolinska Institutet have been awarded grants in the Swedish Childhood Cancer Foundation's latest call for funding, during which approximately SEK 62 million was allocated.

19 Apr 2018

People diagnosed with traumatic brain injury may have increased risk of Parkinson's disease, shows study

People who have been diagnosed with a mild concussion, or mild traumatic brain injury, may have a 56 percent increased risk of developing Parkinson's disease, according to a study published in the April 18, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

19 Apr 2018

Researcher presents case study of asymptomatic patient with severe mitral regurgitation

In primary mitral regurgitation there are anatomic abnormalities of the mitral valve causing backward flow, placing a hemodynamic burden on the left ventricle.

19 Apr 2018

Researchers use optogenetics to treat chronic pain

The finger prick from a thorn generates an immediate sensory response. In that instant, neurons at the injury site fire an electrical signal along a nerve fiber to the central nervous system. Our brain notes to avoid further encounters with thorns and the painful insult subsides.

18 Apr 2018

Functional connectivity MRI could help detect brain disorders and diseases

There are no laboratory tests to diagnose migraines, depression, bipolar disorder and many other ailments of the brain. Doctors typically gauge such illnesses based on self-reported symptoms and behavior.

18 Apr 2018

Novel stem cell therapy may transform current paradigms for treating heart failure patients

Clinical trial planning is underway at MedStar Heart & Vascular Institute to determine whether a novel stem cell therapy will improve heart function for patients with heart failure.

18 Apr 2018

Compound derived from immune cells treats psoriasis in mice

A compound derived from immune cells treats psoriasis in mice and holds promise for other autoimmune diseases, according to a new study from Washington University School of Medicine in St. Louis.

18 Apr 2018

Nanodisc-delivered cancer treatment helps eliminate tumors

In the wrestling match with cancer, chemoimmunotherapy is the new strong arm, and it is building muscle with a nanodisc disguised as "good cholesterol."

18 Apr 2018

Experts propose new solutions to increase benefit, affordability of targeted cancer medicines

Spending on cancer drugs in the United States has nearly doubled in the past five years and continues to grow, imposing substantial financial burden on patients with cancer.

18 Apr 2018

'Gut-on-a-chip' model recreates intestinal matrix critical for nutrient absorption

The difficulties of conducting research on the human gut are substantial: the presence of trillions of bacterial cells interacting with human cells and each other, constant environmental changes every time food is consumed and zero chance of conducting trials that control for all those moving parts.

18 Apr 2018

Novel method enables fast and noninvasive assessment of tumor status

How aggressive is a tumor? To measure the tumor status without taking tissue samples, Italian researchers have developed a method based on magnetic resonance imaging (MRI) of whole body parts.

18 Apr 2018

Medical Condition News

Interaction between dioxin and HLA gene variant activates events associated with rheumatoid arthritis

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

Study shows testosterone deficiency in men is associated with chronic diseases

Environmental pollutants found to worsen rheumatoid arthritis

Study highlights need for further evidence to improve symptom management in end of life care

Finding the 'keyhole' to beat obesity at the cellular level

Case study shows how intravascular ultrasound imaging helps detect acute aortic syndrome

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Genome editing identifies neural circuit behind leptin’s anti-obesity and anti-diabetes effects

The Swedish Childhood Cancer Foundation awards grant to KI researchers

People diagnosed with traumatic brain injury may have increased risk of Parkinson's disease, shows study

Researcher presents case study of asymptomatic patient with severe mitral regurgitation

Researchers use optogenetics to treat chronic pain

Functional connectivity MRI could help detect brain disorders and diseases

Novel stem cell therapy may transform current paradigms for treating heart failure patients

Compound derived from immune cells treats psoriasis in mice

Nanodisc-delivered cancer treatment helps eliminate tumors

Experts propose new solutions to increase benefit, affordability of targeted cancer medicines

'Gut-on-a-chip' model recreates intestinal matrix critical for nutrient absorption

Novel method enables fast and noninvasive assessment of tumor status

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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