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Adipocytes may reduce effectiveness of chemotherapeutic drug

Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.

8 Nov 2017

Study finds link between lupus and elevated risk of dementia

A new International Journal of Geriatric Psychiatry study indicates that the risk of dementia may be elevated in individuals with systemic lupus erythematosus (SLE), an autoimmune disease affecting a range of systems including the peripheral and central nervous system.

8 Nov 2017

Overabundance of gut bacteria may exacerbate pain in patients with sickle cell disease

An overabundance of the bacteria Veillonella in the digestive tract may increase pain in patients with sickle cell disease (SCD).

8 Nov 2017

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.

8 Nov 2017

New program targets cancers affecting the liver and bile ducts

Cancers affecting the liver and bile ducts will be the target of a new program at Perlmutter Cancer Center at NYU Langone Health to provide multidisciplinary clinical care and rapidly bring important new research to the clinic.

7 Nov 2017

New category of immunotherapy appears safe to use in patients with both cancer and HIV

A new category of immunotherapies called checkpoint inhibitors that has been highly effective against many different cancers appears safe to use in patients with both advanced malignancies and HIV, a population excluded from earlier trials of such therapies, according to an early-phase trial.

7 Nov 2017

Researchers find new way to restrict ability of cancer to use glucose for energy

Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy.

7 Nov 2017

SLU researcher reports success in identifying new drug targets for muscular dystrophy

In a recent paper published in the journal Skeletal Muscle, a Saint Louis University researcher reports success in identifying new drug targets that potentially could slow or halt the progression of a form muscular dystrophy, an illness characterized by progressive muscle degeneration.

7 Nov 2017

Weight bias may hinder bariatric patients from receiving appropriate care

Health care providers should look beyond body mass index when providing care to patients with obesity, according to an article in AACN Advanced Critical Care.

7 Nov 2017

Research shows high risk for cardiovascular and kidney disease in people with HIV

HIV patients and their doctors are urged to be more aware of the additional health risks associated with treated HIV infection. This follows new research that shows HIV patients at high risk for a heart attack or stroke are also at substantially greater risk for chronic kidney disease and vice versa.

7 Nov 2017

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

Stem cells taken from muscle tissue could promote better blood flow in patients with diabetes who develop peripheral artery disease, a painful complication that can require surgery or lead to amputation.

7 Nov 2017

Genotype may help identify patients at increased risk for sickle cell disease-related complications

Researchers have found a genotype that could help identify sickle cell disease (SCD) patients at greatest risk of common, yet severe, complications of SCD.

7 Nov 2017

Study reveals link between circulating tumor cells and relapse in late-stage melanoma patients

A study revealing a connection between circulating tumor cells (CTCs) and relapse in stage IV melanoma patients points to liquid biopsy as a potential predictor of patients at high risk for disease progression. CTCs, tumor cells shed into the bloodstream or lymphatic system, can lead to additional tumor growth and/or metastasis to distant sites.

7 Nov 2017

SBP researchers identify new protective function for brain protein genetically linked to Alzheimer's

Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a new protective function for a brain protein genetically linked to Alzheimer's. The findings, published in the Journal of Experimental Medicine, could inform novel treatment strategies.

7 Nov 2017

New study finds enhanced impact of drug combination for FAP patients

People with an inherited syndrome called familial adenomatous polyposis (FAP) have a 100% lifetime risk of developing colorectal cancer if they do not seek appropriate medical care.

7 Nov 2017

Study finds link between increased brain glucose levels and Alzheimer's

A new study published yesterday in Alzheimer's & Dementia: the Journal of the Alzheimer's Association, found a link for the first time between abnormalities in the mechanism of glucose breakdown in the brain and the severity of tangles and amyloid plaques in the brain, as well as the commencement of visible symptoms of Alzheimer's disease.

7 Nov 2017

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD).

7 Nov 2017

Mental stress and anticipation of pain may trigger painful sickle cell episodes

Mental stress and the anticipation of pain may cause blood vessels to narrow and trigger episodes of severe pain (vaso-occlusive crisis, or VOC) in sickle cell disease (SCD).

7 Nov 2017

High protein diet may have deleterious long-term impact on kidney health

High protein diets may lead to long-term kidney damage among those suffering from chronic kidney disease, according to research led by nephrologist Kamyar Kalantar-Zadeh, MD, MPH, PhD, of the University of California, Irvine.

7 Nov 2017

Researchers identify mechanisms through which H. pylori bacteria cause gastric cancer

Gastric cancer is one of the five most fatal types of cancer. According to the statistics of the World Health Organization, about 750,000 patients die each year after developing the disease. The main cause is thought to be the bacterium Helicobacter pylori (H. pylori).

7 Nov 2017

Medical Condition News

Adipocytes may reduce effectiveness of chemotherapeutic drug

Study finds link between lupus and elevated risk of dementia

Overabundance of gut bacteria may exacerbate pain in patients with sickle cell disease

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

New program targets cancers affecting the liver and bile ducts

New category of immunotherapy appears safe to use in patients with both cancer and HIV

Researchers find new way to restrict ability of cancer to use glucose for energy

SLU researcher reports success in identifying new drug targets for muscular dystrophy

Weight bias may hinder bariatric patients from receiving appropriate care

Research shows high risk for cardiovascular and kidney disease in people with HIV

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

Genotype may help identify patients at increased risk for sickle cell disease-related complications

Study reveals link between circulating tumor cells and relapse in late-stage melanoma patients

SBP researchers identify new protective function for brain protein genetically linked to Alzheimer's

New study finds enhanced impact of drug combination for FAP patients

Study finds link between increased brain glucose levels and Alzheimer's

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

Mental stress and anticipation of pain may trigger painful sickle cell episodes

High protein diet may have deleterious long-term impact on kidney health

Researchers identify mechanisms through which H. pylori bacteria cause gastric cancer

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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