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Study sheds new light on how anti-cancer agent inhibits tumor growth

Researchers at Sanford Burnham Prebys Medical Discovery Institute have published a study in Nature Communications shedding new light on how K-80003 (TX803), an anti-cancer agent discovered at the Institute, prevents activation of the PI3K pathway, resulting in inhibition of cancer cell growth.

4 Aug 2017

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Omeros Corporation today announced that OMS721 has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A (IgA) nephropathy.

4 Aug 2017

Modifying gene expression may provide path to preventive treatments for heart failure, study suggests

Heart failure refers to a condition in which heart muscle becomes weakened over time, making it increasingly difficult for the heart to pump blood through the body like it should.

4 Aug 2017

Cellular aging process can promote idiopathic pulmonary fibrosis

Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence. This has been shown by researchers from the Helmholtz Zentrum München, partner in the German Center for Lung Research.

4 Aug 2017

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

Scientists from The Institute of Cancer Research, London has developed a new test through which women at a greater risk of relapsing from breast cancer within 10 years of diagnosis can be identified.

4 Aug 2017

Protein that protects fetus during pregnancy could help treat atopic dermatitis

A protein which protects the fetus during pregnancy, HLA-G1, shows high potential for treating atopic dermatitis and other related diseases.

4 Aug 2017

Researchers explore why physicians underprescribe drug approved to treat opioid addiction

A drug approved for private physicians to treat opioid addiction is being underprescribed, and a survey of addiction specialists suggests that many of them are not willing to increase their use of it, despite an expanding opioid addiction epidemic in the United States, according to research presented at the 125th Annual Convention of the American Psychological Association.

4 Aug 2017

Study finding provides new target besides the brain to develop therapies for sleep disorders

Scientists exploring the brain for answers to certain sleep disorders may have been looking in the wrong place.

4 Aug 2017

Smell loss linked to worse nutritional status in patients with chronic kidney disease

A new study indicates that many patients with chronic kidney disease (CKD) have some degree of smell loss, and that impairments in patients' ability to smell are linked with worse nutritional status.

4 Aug 2017

Breakthrough research brings cognitive hearing aids a step closer to reality

People who are hearing impaired have a difficult time following a conversation in a multi-speaker environment such as a noisy restaurant or a party. While current hearing aids can suppress background noise, they cannot help a user listen to a single conversation among many without knowing which speaker the user is attending to.

4 Aug 2017

UAMS scientists awarded $422,610 NSF grant to study regulation of emotion

A team of University of Arkansas for Medical Sciences research scientists recently received a $422,610 grant from the National Science Foundation to study the mechanisms of control of emotional responses of men and women using functional magnetic resonance imaging (fMRI).

3 Aug 2017

Experimental drug protects mice from obesity-related liver disease

A drug developed at the University of Rochester Medical Center protected mice from one of the many ills of our cheeseburger and milkshake-laden Western diet -- non-alcoholic fatty liver disease.

3 Aug 2017

Studies show how endoscopic procedures can improve outcomes and care

Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy, features a study reporting that a simpler procedure for collecting biopsy specimens during various procedures can improve patient care, and a study showing how a relatively new procedure, POEM, has been adapted to help an additional set of patients with gastroparesis, a troubling stomach problem.

3 Aug 2017

Protein-rich diet may foster more tolerant, less inflammatory gut environment

Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don't sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues.

3 Aug 2017

Yoga appears to lessen symptoms of depression

People who suffer from depression may want to look to yoga as a complement to traditional therapies as the practice appears to lessen symptoms of the disorder, according to studies presented at the 125th Annual Convention of the American Psychological Association.

3 Aug 2017

UVA researchers identify connection between dopamine neurons and brain’s circadian center

Neurons in the brain that produce the pleasure-signaling neurotransmitter dopamine also directly control the brain's circadian center, or "body clock" - the area that regulates eating cycles, metabolism and waking/resting cycles - a key link that possibly affects the body's ability to adapt to jet lag and rotating shift work, a new University of Virginia study has demonstrated.

3 Aug 2017

FDA approves fixed dose combination chemotherapy for subtypes of AML that have poor survival outcomes

The U.S. Food and Drug Administration (FDA) yesterday approved Vyxeos - a fixed dose combination chemotherapy for the treatment of adults with two types of acute myeloid leukemia (AML). The types of AML that would be treated with Vyxeos include newly diagnosed therapy-related AML (t-AML) and AML with myelodysplasia-related changes (AML-MRC). Vyxeos is a fixed-combination of the chemotherapy drugs daunorubicin and cytarabine.

3 Aug 2017

FDA approves new combo drug Mavyret for adults with Hepatitis C infection

Yesterday the U.S. Food and Drug Administration gave its approval to Mavyret (glecaprevir and pibrentasvir) for the treatment of adults with chronic hepatitis C infection. These patients are infected with the Hepatitis C virus (HCV) of genotypes 1-6 and are those that have not developed liver cirrhosis or those who have developed mild cirrhosis. The approval for Mavyret was given to AbbVie Inc.

3 Aug 2017

Gene-therapy administered through skin transplants could enable treatment of many diseases

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases.

3 Aug 2017

Shrinking Salton Sea contributes to dust sources with potential to impact human health

Scientists at the University of California, Riverside investigating the composition of particulate matter (PM) and its sources at the Salton Sea have found that this shrinking lake in Southern California is exposing large areas of dry lakebed, called playa, that are acting as new dust sources with the potential to impact human health.

3 Aug 2017

Medical Condition News

Study sheds new light on how anti-cancer agent inhibits tumor growth

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Modifying gene expression may provide path to preventive treatments for heart failure, study suggests

Cellular aging process can promote idiopathic pulmonary fibrosis

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

Protein that protects fetus during pregnancy could help treat atopic dermatitis

Researchers explore why physicians underprescribe drug approved to treat opioid addiction

Study finding provides new target besides the brain to develop therapies for sleep disorders

Smell loss linked to worse nutritional status in patients with chronic kidney disease

Breakthrough research brings cognitive hearing aids a step closer to reality

UAMS scientists awarded $422,610 NSF grant to study regulation of emotion

Experimental drug protects mice from obesity-related liver disease

Studies show how endoscopic procedures can improve outcomes and care

Protein-rich diet may foster more tolerant, less inflammatory gut environment

Yoga appears to lessen symptoms of depression

UVA researchers identify connection between dopamine neurons and brain’s circadian center

FDA approves fixed dose combination chemotherapy for subtypes of AML that have poor survival outcomes

FDA approves new combo drug Mavyret for adults with Hepatitis C infection

Gene-therapy administered through skin transplants could enable treatment of many diseases

Shrinking Salton Sea contributes to dust sources with potential to impact human health

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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