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Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School of Medicine researchers report in a study published online today in Nature Biotechnology.

2 May 2017

Powerful pain medicine may help reduce vision damage of glaucoma

The tip of our optic nerve is typically the first place injured by glaucoma. Now researchers want to know if the powerful pain medicine (+)-pentazocine can help avoid the damage.

2 May 2017

Study highlights risk factors for widespread vitamin D deficiency

Results from a clinical review published in The Journal of the American Osteopathic Association find nearly 1 billion people worldwide may have deficient or insufficient levels of vitamin D due to chronic disease and inadequate sun exposure related to sunscreen use.

2 May 2017

Telephone interventions following ED discharge can reduce suicide attempts

In perhaps the largest national suicide intervention trial ever conducted, researchers at the University of Colorado Anschutz Medical Campus and Brown University found that phone calls to suicidal patients following discharge from Emergency Departments led to a 30 percent reduction in future suicide attempts.

2 May 2017

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

A noninvasive PET imaging method that measures granzyme B, a protein released by immune cells to kill cancer cells, was able to distinguish mouse and human tumors that responded to immune checkpoint inhibitors from those that did not respond early in the course of treatment.

1 May 2017

Study explores precision psychiatry approaches to improve outcomes for patients with depression

A new study in Personalized Medicine in Psychiatry explores how specific clinical and biological signals can help doctors select the most effective drug more quickly and with greater precision.

1 May 2017

Special issue of Evidence-Based Oncology focuses on benefits and challenges of APMs in cancer care

The revolution in how physicians will be paid brings unique challenges to cancer care, where individual patient needs may make costs hard to predict.

29 Apr 2017

MDI Biological Laboratory investigator awarded NIH grant for research on peripheral neuropathy

The MDI Biological Laboratory has announced that Sandra Rieger, Ph.D., has been awarded a highly competitive grant from the National Cancer Institute, an institute of the National Institutes of Health, to study the molecular mechanisms underlying chemotherapy-induced peripheral neuropathy, a side effect of cancer chemotherapy causing symptoms such as pain, tingling, temperature sensitivity and numbness in the extremities.

29 Apr 2017

Scientists launch new virtual platform to aid global search for treatment of leukemia

Finding a cure for a rare type of blood cancer could be accelerated by a new virtual platform that allows researchers easy access to data from patient samples generated by laboratories around the world.

29 Apr 2017

New book offers guidance on how to deliver systematic approaches in forensic music therapy

‘The Clinician's Guide to Forensic Music Therapy’ by Dr Stella Compton Dickinson and Dr Laurien Hakvoort, is the first book to offer clear, evidence-based manuals for forensic music therapists in the treatment and recovery of men and women in secure hospitals and prisons.

29 Apr 2017

Study describes new targets for precision treatment of meningiomas

Winner of the Integra Foundation Award, Mark W. Youngblood, presented his research, Clinical and Molecular Features of Genomic Subgroups in Meningioma, during the 2017 American Association of Neurological Surgeons Annual Scientific Meeting.

29 Apr 2017

ARDS survivors who return to work end up losing their jobs, study finds

Forty-four percent of people who held jobs before contracting a condition called acute respiratory distress syndrome were jobless one year after they were discharged from the hospital, costing them an average of about $27,000 in earnings.

29 Apr 2017

Study examines economic impact of surviving acute respiratory distress syndrome

According to a new multicenter study, nearly half of previously employed adult survivors of acute respiratory distress syndrome were jobless one year after hospital discharge, and are estimated to have lost an average of $27,000 in earnings.

28 Apr 2017

UM SOM expert diagnoses severe illness that destroyed hearing of Spanish artist

Francisco Goya is the most important Spanish artist of the late 18th and early 19th century. He was famed for his sensitive portraits, and many historians argue that he was the first truly modern painter.

28 Apr 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

FDA approves new drug and chemotherapy combination for treatment of adult patients with AML

The U.S. Food and Drug Administration today approved Rydapt (midostaurin) for the treatment of adult patients with newly diagnosed acute myeloid leukemia who have a specific genetic mutation called FLT3, in combination with chemotherapy.

28 Apr 2017

Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

Cleveland Clinic doctors have published the first study illustrating the safety and efficacy of endoscopic needle knife therapy for intestinal strictures in patients with inflammatory bowel disorder.

28 Apr 2017

New prognostic tool accurately predicts recurrence of parathyroid cancer

A newly-created prognostic tool reliably predicts the recurrence of parathyroid cancer, enabling physicians to identify patients at the highest risk.

28 Apr 2017

Study shows how antibiotic treatments may offset beneficial effects of whole grain intake

According to recommendations from the Danish Veterinary and Food Administration, adult Danes should consume at least 75 g whole meal a day.

28 Apr 2017

Experts defy exclusion of acupuncture in two British governmental guidelines

Even as news in the United States recently highlighted the growing inclusion of acupuncture and other complementary and integrative medicine therapies in guidelines for multiple pain conditions, the exclusion of acupuncture in two British governmental guidelines is challenged in a paper and a commentary that are presently available free on The Journal of Alternative and Complementary Medicine website until May 29, 2017.

28 Apr 2017

Medical Condition News

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

Powerful pain medicine may help reduce vision damage of glaucoma

Study highlights risk factors for widespread vitamin D deficiency

Telephone interventions following ED discharge can reduce suicide attempts

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

Study explores precision psychiatry approaches to improve outcomes for patients with depression

Special issue of Evidence-Based Oncology focuses on benefits and challenges of APMs in cancer care

MDI Biological Laboratory investigator awarded NIH grant for research on peripheral neuropathy

Scientists launch new virtual platform to aid global search for treatment of leukemia

New book offers guidance on how to deliver systematic approaches in forensic music therapy

Study describes new targets for precision treatment of meningiomas

ARDS survivors who return to work end up losing their jobs, study finds

Study examines economic impact of surviving acute respiratory distress syndrome

UM SOM expert diagnoses severe illness that destroyed hearing of Spanish artist

Takeda announces accelerated approval from FDA for new lung cancer treatment

FDA approves new drug and chemotherapy combination for treatment of adult patients with AML

Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

New prognostic tool accurately predicts recurrence of parathyroid cancer

Study shows how antibiotic treatments may offset beneficial effects of whole grain intake

Experts defy exclusion of acupuncture in two British governmental guidelines

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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