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Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research, an American Heart Association journal.

11 May 2016

Osaka University researchers find way for early detection of AD

Kichitaro Nakajima, a graduate student at the Graduate School of Engineering Science, Hirotsugu Ogi, Associate Professor at the Graduate School of Engineering Science, and Yuji Goto, Professor at Institute for Protein Research, Osaka University succeeded in increasing the velocity constant for a reaction in which proteins causing Alzheimer disease (AD) turn into toxic substances to 1,000 times by using optimum frequency of ultrasonic irradiation.

11 May 2016

Set of 16 different substances in the breath can help identify IBS patients

There is currently no specific diagnostic test for irritable bowel syndrome (IBS), but now researchers have identified a combination of 16 different substances in the breath that, when measured together, can accurately distinguish IBS patients from people without the condition.

11 May 2016

Non-invasive 3-D virtual heart assessment tool can help predict arrhythmia risk in patients

When electrical waves in the heart run amok in a condition called arrhythmia, sudden death can occur. To save the life of a patient at risk, doctors currently implant a small defibrillator to sense the onset of arrhythmia and jolt the heart back to a normal rhythm.

11 May 2016

Majority of patients who misuse drugs and alcohol have chronic pain

With opioid addiction and prescription drug abuse considered one of the biggest public health threats of our time in the U.S., many are asking why so many Americans are struggling with addiction to illegal drugs and prescription medications. New research suggests that chronic pain may be part of the answer.

10 May 2016

Celiac disease more common among Americans with Punjabi ancestry, study shows

About 1.8 million Americans have celiac disease, an immune-based condition brought on by the consumption of gluten in genetically susceptible patients. Among patients diagnosed with celiac disease by small intestinal biopsy in the U.S., those from the Punjab region of India have the highest rates of disease, according to new research published in Clinical Gastroenterology and Hepatology,1 the official clinical practice journal of the American Gastroenterological Association.

10 May 2016

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strategies offer limited protection. In the first of its kind, a report in The American Journal of Pathology describes a potential new intraocular treatment based on manipulating the renin angiotensin system (RAS) that both prevents and reverses some characteristics of diabetic retinopathy in a mouse model.

10 May 2016

Researchers identify new psychological disorder, maladaptive maydreaming

A new psychological disorder has been identified in a series of recently published studies - Maladaptive Maydreaming (MD). Researchers from the University of Haifa, in Israel, Fordham University in New York City and University of Lausanne, Switzerland, have found that people with the disorder spend an average of 60% of their waking time in an imaginary world which they themselves have created, realizing that it is a fantasy, and without losing contact with the real world.

10 May 2016

Profiling gamma-retrovirus integration sites may help identify genes linked to specific cancer types

Identifying the sites where gamma-retroviruses commonly insert into the genome may help to identify genes associated with specific cancer types, according to a study published April 20, 2016 in the open-access journal PLOS ONE by Kathryn Gilroy at the University of Glasgow, UK, and colleagues.

10 May 2016

UCLA neurologist highlights steps that can help Americans reduce stroke risk

Getting more exercise, giving up cigarettes and monitoring cholesterol and blood pressure are a few steps Americans can take to reduce their risk of stroke, says Doojin Kim, MD, a neurologist at UCLA Medical Center, Santa Monica who often treats patients who have suffered a stroke, the No. 4 cause of death and the No. 1 cause of adult disability in the U.S.

10 May 2016

Study shows risk of developing MDD depends on symptom centrality in network

A novel study published in the current issue of Psychotherapy and Psychosomatics discloses how depression may develop.

10 May 2016

Study highlights role of specific chromosomal deletion in cancer development, progression

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

10 May 2016

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that mindfulness based cognitive therapy (MBCT) is most helpful when antidepressant drugs are not used.

10 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

A new study on the epigenetics of lactose intolerance may provide an approach to understanding schizophrenia and other complex, serious illnesses

10 May 2016

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

A recent study reported in the May issue of the Journal of Nuclear Medicine demonstrates that Ga-68 DOTATATE PET/CT scans are superior to In-111 pentetreotide scans, the current imaging standard in the United States for detecting neuroendocrine tumors, and could significantly impact treatment management.

10 May 2016

Transcranial direct current stimulation proves effective for binge-eating disorder

Transcranial direct current stimulation, or tDCS, has proved effective for binge-eating disorder for the first time, according to researchers at the University of Alabama at Birmingham.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Medical Condition News

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Chronic use of antacid drugs may speed up aging of blood vessels

Osaka University researchers find way for early detection of AD

Set of 16 different substances in the breath can help identify IBS patients

Non-invasive 3-D virtual heart assessment tool can help predict arrhythmia risk in patients

Majority of patients who misuse drugs and alcohol have chronic pain

Celiac disease more common among Americans with Punjabi ancestry, study shows

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Researchers identify new psychological disorder, maladaptive maydreaming

Profiling gamma-retrovirus integration sites may help identify genes linked to specific cancer types

UCLA neurologist highlights steps that can help Americans reduce stroke risk

Study shows risk of developing MDD depends on symptom centrality in network

Study highlights role of specific chromosomal deletion in cancer development, progression

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

Transcranial direct current stimulation proves effective for binge-eating disorder

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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