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Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Researchers from Massachusetts Eye and Ear/Harvard Medical School have conducted a clinical trial comparing the safety and efficacy of topical tacrolimus, an immunosuppressive therapy, and topical methylprednisolone, a steroid medication, in patients with ocular graft-versus-host-disease (GVHD) -- a complication associated with allogeneic bone marrow transplants in which the transplanted immune system's cells attack certain parts of the recipient's body, including the cornea and ocular surface.

16 Apr 2016

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans.

16 Apr 2016

Newly developed implantable device can deliver chemotherapy drugs directly to pancreatic tumors

Pancreatic cancer is the third leading cause of cancer deaths in the United States, in part because it is very difficult for chemotherapy drugs to reach the pancreas, which is located deep within the abdomen.

16 Apr 2016

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

A nationwide study of 2.3 million Israeli adolescents, examined from 1967 through 2010, finds an association between elevated body-mass index in late adolescence, and subsequent cardiovascular mortality in midlife.

16 Apr 2016

Inflammation after stroke may help the brain to self-repair

After a stroke, there is inflammation in the damaged part of the brain. Until now, the inflammation has been seen as a negative consequence that needs to be abolished as soon as possible. But, as it turns out, there are also some positive sides to the inflammation, and it can actually help the brain to self-repair.

16 Apr 2016

Experts launch mhNOW initiative to bring proven mental health solutions to people most in need

Today, the Mental Health Now, or mhNOW, initiative will launch at the inaugural Financing and Innovation in Global Health (FIGH) conference. Led by mental health experts Chris Underhill, founder and president of BasicNeeds, and Moitreyee Sinha, head of health at the Global Development Incubator (GDI), mhNOW is a global, collective action including social entrepreneurs, organizations and companies that are working together to innovate and identify mental health solutions on a global scale, and systemically implement in communities at a local level.

15 Apr 2016

Study to test effectiveness of worksite exercise regimen to reduce low back injury risk in firefighters

The University of South Florida and Tampa Fire Rescue have launched a randomized controlled trial to assess the effectiveness of a worksite exercise regimen targeted to reduce the risk of low back injury and disability in firefighters -- a physically demanding occupation particularly prone to back problems that can lead to chronic pain and early retirement.

15 Apr 2016

NeuroLife device helps paralyzed man to perform complex functional movements

Six years ago, he was paralyzed in a diving accident. Today, he participates in clinical sessions during which he can grasp and swipe a credit card or play a guitar video game with his own fingers and hand. These complex functional movements are driven by his own thoughts and a prototype medical system that are detailed in a study published online today in the journal Nature.

15 Apr 2016

Study examines use of cryoablation to reduce phantom limb pain

J. David Prologo, MD, delivered new findings from an Emory Interventional Radiology and Image Guided Medicine study at the Society of Interventional Radiology's 2016 Annual Scientific Meeting. The study examines the use of cryoablation, or extreme cold, to reduce phantom limb pain (PLP) - a condition that causes individuals to perceive chronic pain in amputated limbs. Emory's study shows interventional radiologists who applied cold blasts to patients suffering from PLP significantly reduced their level of pain.

15 Apr 2016

California’s effort to reduce stigma of mental health issues provides positive economic benefits

California's investment in a social marketing campaign to reduce stigma and discrimination associated with mental illness may provide the state with positive economic benefits by increasing employment and worker productivity, according to a new RAND Corporation study.

15 Apr 2016

New classifier method may improve diagnosis of autism spectrum disorders

Many doctors and scientists think they could improve the diagnosis and understanding of autism spectrum disorders if they had reliable means to identify specific abnormalities in the brain.

15 Apr 2016

Improving body clock could protect against metabolic syndrome

Essential biological processes are managed by an internal timer or body clock. When the body clock gets out of whack, conditions such as metabolic syndrome can occur.

15 Apr 2016

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the April 2016 issue of Translational Research suggest that the M10 peptide could help protect against fibrotic damage in patients with systemic sclerosis, particularly in those who develop interstitial lung diseases (ILD), its deadliest complication.

15 Apr 2016

UNIGE researchers identify PIGG gene that plays crucial role in recessive disease

The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects.

15 Apr 2016

Unmet nursing care linked to higher risk of AMI readmissions for older black patients

Why are black older adults at higher risk of repeat hospital admission after a heart attack? Treatment at hospitals with higher rates of missed nursing care may be a contributing factor, reports a study in the May issue of Medical Care. The journal is published by Wolters Kluwer.

15 Apr 2016

AstraZeneca reports new Phase I extended follow-up data on osimertinib in NSCLC patients at ELCC 2016

AstraZeneca today reported new Phase I extended follow-up data on osimertinib in both first- and second-line treatment of patients with non-small cell lung cancer (NSCLC), at the European Lung Cancer Conference (ELCC) 2016. Late-breaker presentations reinforced the efficacy and safety profile for osimertinib previously seen in the AURA clinical trials programme.

15 Apr 2016

Home screening for bowel cancer: an interview with Deborah Alsina, Chief Executive of Bowel Cancer UK

FIT (faecal immunochemical test) is a screening test for bowel cancer which detects hidden traces of blood in stools. It is now used in population screening around the world including Italy, The Netherlands, France, Ireland, New Zealand, Australia, Spain, Slovenia, Malta, Japan, parts of Canada, and Southeast Asia.

14 Apr 2016

SU2C Catalyst program to accelerate research on cancer prevention, detection and treatment

Stand Up To Cancer, the charitable initiative aimed at bringing new treatments to cancer patients quickly, today announced Catalyst, a new program that will use funding and materials from the pharmaceutical, biotechnology, diagnostic and medical devices industries to accelerate research on cancer prevention, detection and treatment.

14 Apr 2016

PITRM1 protein may be involved in development of Alzheimer's disease

University of Bergen researchers have found a protein that could hold the key to understanding how Alzheimer's disease develops.

14 Apr 2016

Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Providing vital health care services to people in developing countries without reliable electricity, refrigeration and state-of-the-art medical equipment poses a number of challenges. Inspired by pregnancy tests, researchers from Florida Atlantic University, Stanford University, and Baskent University in Turkey, have developed a novel method to store microfluidic devices for CD4 T cell testing in extreme weather conditions for up to six months without refrigeration.

14 Apr 2016

Medical Condition News

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

Newly developed implantable device can deliver chemotherapy drugs directly to pancreatic tumors

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

Inflammation after stroke may help the brain to self-repair

Experts launch mhNOW initiative to bring proven mental health solutions to people most in need

Study to test effectiveness of worksite exercise regimen to reduce low back injury risk in firefighters

NeuroLife device helps paralyzed man to perform complex functional movements

Study examines use of cryoablation to reduce phantom limb pain

California’s effort to reduce stigma of mental health issues provides positive economic benefits

New classifier method may improve diagnosis of autism spectrum disorders

Improving body clock could protect against metabolic syndrome

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

UNIGE researchers identify PIGG gene that plays crucial role in recessive disease

Unmet nursing care linked to higher risk of AMI readmissions for older black patients

AstraZeneca reports new Phase I extended follow-up data on osimertinib in NSCLC patients at ELCC 2016

Home screening for bowel cancer: an interview with Deborah Alsina, Chief Executive of Bowel Cancer UK

SU2C Catalyst program to accelerate research on cancer prevention, detection and treatment

PITRM1 protein may be involved in development of Alzheimer's disease

Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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