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Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma.

21 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

Two-way communication between cancer cells may be key to tumor metastasis

Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.

21 May 2016

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Intensive therapies to reduce high blood pressure can cut the risk of heart disease in older adults without increasing the risk for falls, according to doctors at Wake Forest Baptist Medical Center.

21 May 2016

Regular use of laxatives may flatten rigidity found in Parkinson's disease

In a recent retrospective analysis, investigators discovered that the year-on-year increase in rigidity found in Parkinson's disease flattened off with the regular use of laxatives to manage constipation.

21 May 2016

Umea University researchers find link between vitamin E and brain tumours

Researchers at Umea University in Sweden and the Cancer Registry of Norway have studied possible causes behind the development of brain tumours.

21 May 2016

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects.

21 May 2016

Friendships, supportive family environments may help protect teens from depression

The importance of friendships and family support in helping prevent depression among teenagers has been highlighted in research from the University of Cambridge.

20 May 2016

Specific monocyte immune cells serve as link between gut bacteria and the brain

A special kind of immune cell serves as an intermediary between gut bacteria and the brain. Dr. Susanne Wolf of the Max Delbruck Center for Molecular Medicine in the Helmholtz Association discovered this in tests on mice and published her findings in the journal Cell Reports.

20 May 2016

Malicious form of ATF2 protein drives formation of melanoma

An international collaborative study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a malicious form of a protein that drives the formation of melanoma.

20 May 2016

New study aims to identify biomarkers linked to cartilage degradation in OA patients

Joint injury can lead to post-traumatic osteoarthritis (PTOA). In fact, about half of all people who rupture the anterior cruciate ligament (ACL) in their knee will develop PTOA within 10-20 years of the injury.

20 May 2016

High levels of p62 protein in liver linked to cancer recurrence

Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival.

20 May 2016

Researchers identify hCRTh2 protein as possible therapeutic target for asthma

Patients with asthma have chronic lung inflammation that results in sporadic narrowing of the airways and difficulty breathing. Symptoms and severity are variable among individuals; however, the cells and inflammatory factors that trigger asthmatic events have been fairly well characterized and are similar regardless of the asthma-inducing stimuli.

20 May 2016

Arthroscopic surgery may not be best option for older, arthritis patients

For patients with serious, ongoing hip pain, sometimes surgery is their best bet for relief. Given the choice between minimally invasive hip surgery and total hip replacement, most patients would choose the less invasive procedure, often done on an outpatient basis.

20 May 2016

Global life expectancy on the rise, but major health inequalities persist

Dramatic gains in life expectancy have been made globally since 2000, but major inequalities persist within and among countries, according to this year’s “World Health Statistics: Monitoring Health for the SDGs”.

20 May 2016

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will provide an update on their extensive oncology pipeline at the annual meeting of the American Society of Clinical Oncology in Chicago, USA, on 3-7 June 2016.

20 May 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Glyphosate, often sold under the brand name of Roundup, is the world's most widely used weed-killer. While Glyphosate has approval from regulatory bodies worldwide, there are growing concerns about its possible adverse health effects.

20 May 2016

Medical Condition News

Phase I study of triple drug combination shows promise in multiple myeloma patients

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Two-way communication between cancer cells may be key to tumor metastasis

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Regular use of laxatives may flatten rigidity found in Parkinson's disease

Umea University researchers find link between vitamin E and brain tumours

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Friendships, supportive family environments may help protect teens from depression

Specific monocyte immune cells serve as link between gut bacteria and the brain

Malicious form of ATF2 protein drives formation of melanoma

New study aims to identify biomarkers linked to cartilage degradation in OA patients

High levels of p62 protein in liver linked to cancer recurrence

Researchers identify hCRTh2 protein as possible therapeutic target for asthma

Arthroscopic surgery may not be best option for older, arthritis patients

Global life expectancy on the rise, but major health inequalities persist

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

New frozen faecal bank increases chances of curing a chronic health condition

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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