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Novel mechanism identified to protect the brain from many neurodegenerative conditions

Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer's disease, and Parkinson's disease.

8 Mar 2016

Leading dementia expert calls for greater public awareness of dementia risk factors

A leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults think it is possible to reduce their risk of developing the condition.

8 Mar 2016

Researchers find new link between elevation of certain amino acids and type 2 diabetes

More than 29 million Americans are currently living with diabetes. The majority have type 2 diabetes, and for them insulin resistance - their body's inability to effectively process sugar - is a part of daily life. Therefore, understanding the cause of insulin resistance is critical to tackling this chronic disease.

8 Mar 2016

Clinician communication increases patient knowledge, relieves distress related to incidental nodule detection

A cross-sectional survey showed a quarter of patients with detected incidental pulmonary nodules experienced significant distress related to the nodule. Detailed clinician communication increased patient knowledge, relieved distress, and improved patient experience.

8 Mar 2016

Cause of amyloid beta pathology may be more versatile than previously known

Accumulation of the substance amyloid beta in the brain impairs the memory and cognitive ability in people with Alzheimer's. New findings from Lund University in Sweden show that the cause of amyloid beta pathology might be more versatile than previously known. Researchers believe that these new findings may be of significance to the development of new medications.

8 Mar 2016

Immune cells play vital role in rewiring connections between nerve cells

A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring the connections between nerve cells.

8 Mar 2016

Low level of physical fitness in early life associated with Type 2 Diabetes risk in adulthood

The combination of low aerobic capacity and low muscle strength at age 18 is associated with a three times greater risk of developing Type 2 Diabetes in adulthood, according to new research from the Icahn School of Medicine at Mount Sinai published online today in the journal Annals of Internal Medicine.

8 Mar 2016

Patients with moderate-to-severe plaque psoriasis achieve significant improvement with ixekizumab

Eli Lilly and Company announced today that patients with moderate-to-severe plaque psoriasis who did not respond to treatment with etanercept achieved significant improvement in their psoriasis plaques when treated with ixekizumab in a Phase 3 clinical trial. Detailed results of the UNCOVER-2 study were presented during the American Academy of Dermatology Annual Meeting taking place March 4-8 in Washington, D.C.

8 Mar 2016

Research could change the way people look at gene expression, immune response

Research from the Single-Cell Genomics Centre on the Wellcome Genome Campus could change the way we look at gene expression and immune response. Published in Nature Methods, the new method, TraCeR, provides a powerful tool for research into immune response, vaccination, cancer and autoimmunity.

8 Mar 2016

Research findings offer new way to look at cancer cell metabolism

Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar.

8 Mar 2016

Providing healthy lifestyle advice reduces risk of heart-related deaths over next 40 years

In a recently published study, providing advice over a 5-year period about leading a healthy lifestyle reduced the risk of heart-related deaths over the next 40 years.

8 Mar 2016

Genetics plays significant role in sleep/wake timing of seizures

New research from the Epilepsy Phenome/Genome Project shows that genetics plays a role in sleep/wake timing of seizures. Researchers studied 1,395 individuals with epilepsy in families containing multiple people with epilepsy to determine whether sleep/wake timing of seizures runs in families.

8 Mar 2016

Research provides important new insights into beginning stages of primary progressive aphasia

The recent ability to peer into the brain of living individuals with a rare type of language dementia, primary progressive aphasia (PPA), provides important new insights into the beginning stages of this disease -- which results in language loss -- when it is caused by a buildup of a toxic protein found in Alzheimer's disease.

8 Mar 2016

VTE patients tend to die earlier from bladder cancer

In a study of 3879 patients who underwent radical cystectomy to treat bladder cancer, 3.6% were diagnosed with a venous thromboembolism (VTE)—which occurs when a blood clot forms in a vein, potentially breaking loose and traveling to the lung—within 1 month of their surgical admission date.

8 Mar 2016

Data traffic may help people better cope with pollution

Heavy city traffic contributes significantly to air pollution and health problems such as asthma, but University of Texas at Dallas researchers think another kind of traffic -- data traffic -- might help citizens better cope with pollution.

8 Mar 2016

ACGT awards new research grants to take researchers to next level in cancer treatment

Alliance for Cancer Gene Therapy, the nation's only nonprofit dedicated exclusively to cell and gene therapies for cancer, is delighted to announce the recipients of its 2016 ACGT Young Investigator Grants.

8 Mar 2016

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

Xencor, Inc., a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, today announced dosing the first patient in a Phase 2 trial of XmAb5871 in patients with IgG4-Related Disease (IgG4-RD).

8 Mar 2016

Specialized tests can help dermatologists provide individualized care for melanoma patients

Melanoma rates in the United States have doubled over the past two decades.1 Fortunately for patients, this increase in melanoma incidence has been accompanied by the development of more effective tools for diagnosis and treatment, including genetic and molecular testing.

7 Mar 2016

Blood test may spot first signs of skin cancer relapse

A BLOOD test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing, according to a study published in the journal Cancer Discovery today (Monday).

7 Mar 2016

Single- and double-bundle techniques may offer similar outcomes for ACL reconstruction patients

Single and double-bundle techniques may provide similar outcomes in patients undergoing ACL reconstruction, as noted in research presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day. The study shows patients in both groups demonstrate similar performance during recovery.

7 Mar 2016

Medical Condition News

Novel mechanism identified to protect the brain from many neurodegenerative conditions

Leading dementia expert calls for greater public awareness of dementia risk factors

Researchers find new link between elevation of certain amino acids and type 2 diabetes

Clinician communication increases patient knowledge, relieves distress related to incidental nodule detection

Cause of amyloid beta pathology may be more versatile than previously known

Immune cells play vital role in rewiring connections between nerve cells

Low level of physical fitness in early life associated with Type 2 Diabetes risk in adulthood

Patients with moderate-to-severe plaque psoriasis achieve significant improvement with ixekizumab

Research could change the way people look at gene expression, immune response

Research findings offer new way to look at cancer cell metabolism

Providing healthy lifestyle advice reduces risk of heart-related deaths over next 40 years

Genetics plays significant role in sleep/wake timing of seizures

Research provides important new insights into beginning stages of primary progressive aphasia

VTE patients tend to die earlier from bladder cancer

Data traffic may help people better cope with pollution

ACGT awards new research grants to take researchers to next level in cancer treatment

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

Specialized tests can help dermatologists provide individualized care for melanoma patients

Blood test may spot first signs of skin cancer relapse

Single- and double-bundle techniques may offer similar outcomes for ACL reconstruction patients

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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