Medical Condition News

RSS

Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients

Ocrelizumab (OCR) is a humanized monoclonal antibody that selectively targets CD20+B cells. In a randomized, double-blind, placebo-controlled Phase III study (ORATORIO), OCR significantly reduced disease activity in patients with primary progressive multiple sclerosis (PPMS).

27 Feb 2016

Discovery highlights need to improve patient education about genomics

An overwhelming majority of people with incurable cancer want to hear findings from DNA sequencing of their own tumors and normal cells, and to learn how those results may affect their health and treatment options, Dana Farber Cancer Institute scientists report.

27 Feb 2016

P. gingivalis could be a novel risk factor for esophageal cancer

University of Louisville School of Dentistry researchers have found a bacterial species responsible for gum disease, Porphyromonas gingivalis, is present in 61 percent of patients with esophageal squamous cell carcinoma (ESCC).

27 Feb 2016

PCSK9-inhibitor drugs: A game-changer for individuals with extremely high cholesterol levels

A 59-year-old heart patient with dangerously high levels of cholesterol that could not be adequately reduced by statin drugs now has near-normal cholesterol levels, thanks to a new class of drugs that grew out of work done by UT Southwestern Medical Center researchers.

27 Feb 2016

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

A new study examines whether recent changes in the use of anemia drugs for patients on dialysis have contributed to changes in rates of death or cardiovascular events. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, indicate that these risks appear to be decreasing for patients on dialysis as well as for older adults (Medicare beneficiaries) who are not on dialysis.

27 Feb 2016

Elevated levels of particular proteins in cancer cells fuel growth and spread of different cancers

Researchers at University of California, San Diego School of Medicine and Moores Cancer Center, with colleagues in Spain and Germany, have unraveled how elevated levels of particular proteins in cancer cells trigger hyperactivity in other proteins, fueling the growth and spread of a variety of cancers.

27 Feb 2016

Potential link between PLCD and ALL could offer new targets for cancer prevention research

A potential correlation between pre-labor cesarean delivery (PLCD) and acute lymphoblastic leukemia (ALL) could offer new targets for cancer prevention research, according to new research from the Masonic Cancer Center, University of Minnesota.

27 Feb 2016

Understanding range of neurological disease linked with Zika virus is urgent priority, warn researchers

Understanding the scale and range of neurological disease associated with Zika virus infection is an urgent priority, warn researchers from the University of Liverpool's Institute of Infection and Global Health.

27 Feb 2016

Radiotherapy plus panobinostat more effective for aggressive, recurrent brain cancer

Radiotherapy effectively damages brain tumors but the cancer cells can repair themselves in order to live on. Now, researchers at Sidney Kimmel Cancer Center have tested a strategy that combines radiotherapy with a drug that shuts down the ability of tumor to mend themselves.

27 Feb 2016

Researchers find way to boost the body's natural cancer-killing cells

The immune cells, called natural killer cells, hunt and destroy foreign cells in the body, including cancer cells that spread and form tumours.

27 Feb 2016

Discovery could lead to better therapies for people with obsessive compulsive disorder

Research led by investigators in veterinary and human medicine has identified genetic pathways that exacerbate severity of canine compulsive disorder in Doberman pinschers, a discovery that could lead to better therapies for obsessive compulsive disorder in people.

27 Feb 2016

Novel therapeutic approach to target monomeric Tau protein

Dementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

27 Feb 2016

Older adults have more positive responses than young adults about feeling serenity, loneliness

A new study led by associate professor Rebecca Ready in the department of psychological and brain sciences at the University of Massachusetts Amherst has found that older adults have different, more positive responses than young adults about feelings such as serenity, sadness and loneliness.

27 Feb 2016

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

For decades, intensive research has been conducted on drugs all over the world to treat Alzheimer's patients. Although major progress has been made in diagnostics (the disease can be detected increasingly early and accurately), the therapeutic options remain limited.

27 Feb 2016

Researchers develop new method to screen tumor samples for presence of human polyomaviruses

Human polyomaviruses are commonly found in the population and generally do not produce noticeable symptoms. However, one type of human polyomavirus, the Merkel cell polyomavirus, is known to cause a rare form of skin cancer called Merkel cell carcinoma, and other members of the polyomavirus family can induce non-cancer related diseases in people with compromised immune systems.

27 Feb 2016

Mice with lymphatic defects develop obesity late in life

Lymphatic vessels play multifaceted roles in the body, including the absorption of dietary lipid in the intestines as well as the movement of immune cells throughout the body. Previous work by Guillermo Oliver and colleagues showed that mice with lymphatic defects due to loss of one copy of the Prox1 gene developed obesity late in life.

27 Feb 2016

Bariatric surgery reduces incidence of heart failure exacerbation in patients with morbid obesity

A new study led by Massachusetts General Hospital investigators finds that heart failure patients who underwent bariatric surgery to treat morbid obesity had a significant reduction in the incidence of heart failure exacerbation - a dangerous, sudden worsening of symptoms - in the two years following surgery.

27 Feb 2016

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments.

27 Feb 2016

New imaging study shows how exercise affects the brain

People who exercise have better mental fitness, and a new imaging study from UC Davis Health System shows why. Intense exercise increases levels of two common neurotransmitters -- glutamate and gamma-aminobutyric acid, or GABA -- that are responsible for chemical messaging within the brain.

27 Feb 2016

Researchers develop effective technique for studying high-arched palate using mouse model

Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality.

27 Feb 2016

Medical Condition News

Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients

Discovery highlights need to improve patient education about genomics

P. gingivalis could be a novel risk factor for esophageal cancer

PCSK9-inhibitor drugs: A game-changer for individuals with extremely high cholesterol levels

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

Elevated levels of particular proteins in cancer cells fuel growth and spread of different cancers

Potential link between PLCD and ALL could offer new targets for cancer prevention research

Understanding range of neurological disease linked with Zika virus is urgent priority, warn researchers

Radiotherapy plus panobinostat more effective for aggressive, recurrent brain cancer

Researchers find way to boost the body's natural cancer-killing cells

Discovery could lead to better therapies for people with obsessive compulsive disorder

Novel therapeutic approach to target monomeric Tau protein

Older adults have more positive responses than young adults about feeling serenity, loneliness

Researchers find way to inhibit enzyme responsible for Alzheimer's disease

Researchers develop new method to screen tumor samples for presence of human polyomaviruses

Mice with lymphatic defects develop obesity late in life

Bariatric surgery reduces incidence of heart failure exacerbation in patients with morbid obesity

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

New imaging study shows how exercise affects the brain

Researchers develop effective technique for studying high-arched palate using mouse model

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Latest News