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LAP defects may lead to lupus-like autoimmune disorder

A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude Children's Research Hospital scientists led the research, which appears as an advance online publication today in the scientific journal Nature.

21 Apr 2016

Study finds links between phthalate exposure and obesity

Exposure to chemicals found in everyday products could affect the amount of fat stored in the body, according to a study by University of Georgia researchers.

21 Apr 2016

Non-invasive optogenetic therapy can help treat chronic pain

The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of McGill University and the McGill University Health Centre.

21 Apr 2016

Savouring positive memories can boost mood in individuals with mental health problems

Researchers from the University of Liverpool have published a study highlighting the effectiveness of using positive memories and images to help generate positive emotions.

21 Apr 2016

Athletes who have psychosomatic symptoms prior to concussion may take longer to recover

Athletes may take longer to recover after concussion if they had experienced psychosomatic symptoms before they became concussed, report researchers.

21 Apr 2016

Proteins can be used as targets to deliver drugs into stressed cancer cells

Targeted missiles that can enter cancer cells and deliver lethal cell toxins without harming surrounding healthy tissue. This has been a long-standing vision in cancer research, but it has proved difficult to accomplish. A research group at Lund University in Sweden has now taken some crucial steps in this direction.

20 Apr 2016

Researchers develop insoles impregnated with silver nanoparticles to treat diabetic foot syndrome

Scientists from Tomsk Polytechnic University and National Autonomous Mexico University develop techniques to treat diabetic foot syndrome with special insoles with silver nano-particles. The techniques help to fight ulcers appearing on feet in diabetic patients, facilitates their healing and disinfection, reducing the risk of amputation.

20 Apr 2016

Strength training lowers odds of death in older adults

Older adults who met twice-weekly strength training guidelines had lower odds of dying in a new analysis by researchers at Penn State College of Medicine, Penn State Health Milton S. Hershey Medical Center and Columbia University. The study is the first to demonstrate the association in a large, nationally representative sample over an extended time period, particularly in an older population.

20 Apr 2016

Adding CYP24A1 inhibitors may improve antitumor activity of vitamin D

Roswell Park Cancer Institute research on the most potent form of vitamin D, commonly called calcitriol, offers new insights into approaches that may enhance the antitumor activity of this much-studied human hormone.

20 Apr 2016

Specific oral microbiome linked to pancreatic cancer risk

The presence of certain bacteria in the mouth may reveal increased risk for pancreatic cancer and enable earlier, more precise treatment. This is the main finding of a study led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center to be presented April 19 in New Orleans at the annual meeting of the American Association for Cancer Research.

20 Apr 2016

Scientists develop new drug for life-threatening lung disease treatment

Researchers are developing a new drug to treat life-threatening lung damage and breathing problems in people with severe infections like pneumonia, those undergoing certain cancer treatments and premature infants with underdeveloped, injury prone lungs.

20 Apr 2016

Study shows pulmonary alveolar proteinosis can be cured by single transfer of monocytes

Researchers from VIB-UGent reveal that adult circulating monocytes that get access to the macrophage niche in the liver or the lung can acquire identical tissue-specific macrophage functions and self-maintenance capacities as macrophages of embryonic origin.

20 Apr 2016

New clinical study to evaluate inexpensive drug to prevent type 1 diabetes

A clinical study evaluating a new hypothesis that an inexpensive drug with a simple treatment regimen can prevent type 1 diabetes will be launched in Dundee tomorrow.

20 Apr 2016

Study shows beneficial effect of hNSC transplantation for TBI

Traumatic brain injury (TBI) is a major cause of mortality and morbidity, often causing lifelong disability for those who survive. Treatment is limited to supportive care, but stem cell therapy has received recent attention as a way to promote recovery for injuries to the central nervous system (CNS). In this study, researchers transplanted human neural stem cells (hNSCs) into the brains of mice modeled with TBI to investigate whether the hosts' immune systems and the stem cells acting in concert would enhance repair.

20 Apr 2016

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

In a clinical trial of the immunotherapy drug pembrolizumab, half of 25 patients with a rare type of virus-linked skin cancer called Merkel cell carcinoma experienced substantial tumor shrinkage lasting nearly three times as long, on average, than with conventional chemotherapy.

20 Apr 2016

Nivolumab drug shows survival benefit in phase III trial of patients with head and neck cancer

The immunotherapy drug nivolumab has become the first to show a survival benefit in head and neck cancer, after a major international trial found that it was more effective than standard chemotherapy.

20 Apr 2016

FDA expands campaign to educate rural, white male teens about dangers of smokeless tobacco use

The U.S. Food and Drug Administration announced today it is expanding its award-winning "The Real Cost" campaign to educate rural, white male teenagers about the negative health consequences associated with smokeless tobacco use. For the first time, messages on the dangers of smokeless tobacco use – including nicotine addiction, gum disease, tooth loss, and multiple kinds of cancer – are being highlighted through the placement of advertisements in 35 U.S. markets specifically selected to reach the campaign's target audience.

20 Apr 2016

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

20 Apr 2016

Researchers evaluate TBI-associated risk factors in older adults

Traumatic brain injury (TBI), a leading cause of death and disability, has become so common in recent times that it has been called a "silent epidemic." And because older adults are more likely to suffer TBI, have worse outcomes, and are less likely to survive their injury than younger adults, older adults are considered a "silent population" within this epidemic.

20 Apr 2016

Herceptin drugs for breast cancer linked with increased risk of congestive heart failure

Breast cancer patients undergoing treatment with trastuzumab-containing regimens should be monitored for heart damage regardless of age. This is among the findings of a new study from the Peter Munk Cardiac Centre, the Institute for Clinical Evaluative Sciences (ICES) and the Ted Rogers Centre for Heart Research, University Health Network.

20 Apr 2016

Medical Condition News

LAP defects may lead to lupus-like autoimmune disorder

Study finds links between phthalate exposure and obesity

Non-invasive optogenetic therapy can help treat chronic pain

Savouring positive memories can boost mood in individuals with mental health problems

Athletes who have psychosomatic symptoms prior to concussion may take longer to recover

Proteins can be used as targets to deliver drugs into stressed cancer cells

Researchers develop insoles impregnated with silver nanoparticles to treat diabetic foot syndrome

Strength training lowers odds of death in older adults

Adding CYP24A1 inhibitors may improve antitumor activity of vitamin D

Specific oral microbiome linked to pancreatic cancer risk

Scientists develop new drug for life-threatening lung disease treatment

Study shows pulmonary alveolar proteinosis can be cured by single transfer of monocytes

New clinical study to evaluate inexpensive drug to prevent type 1 diabetes

Study shows beneficial effect of hNSC transplantation for TBI

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

Nivolumab drug shows survival benefit in phase III trial of patients with head and neck cancer

FDA expands campaign to educate rural, white male teens about dangers of smokeless tobacco use

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

Researchers evaluate TBI-associated risk factors in older adults

Herceptin drugs for breast cancer linked with increased risk of congestive heart failure

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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