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Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Allergan plc., a leading global pharmaceutical company today announced that its Phase III ready investigational medication rapastinel (GLYX-13) received Breakthrough Therapy designation from the U.S. Food and Drug Administration for adjunctive treatment of Major Depressive Disorder (MDD).

29 Jan 2016

Adhering to certain diet may help postpone need for dialysis in CKD patients

Adhering to a certain diet may help postpone the need for dialysis in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

29 Jan 2016

Weight loss programs that provide healthy fats have similar impacts on pound-shedding

A University of California, San Diego School of Medicine study finds that weight loss programs that provide healthy fats, such as olive oil in the Mediterranean diet, or a low-fat, high-carbohydrate diet have similar impacts on pound-shedding.

29 Jan 2016

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen.

29 Jan 2016

Access for new melanoma treatment remains uncertain for patients despite UK launch

Novartis announced today that Tafinlar (dabrafenib) + Mekinist (trametinib), the first oral combination therapy to be licensed for advanced melanoma, is now available in the UK for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.

29 Jan 2016

UCLA researchers find protein combination that could improve clinical bone restoration

A UCLA research team has found a combination of proteins that could significantly improve clinical bone restoration. The findings may be a big step toward developing effective therapeutic treatments for bone skeletal defects, bone loss and osteoporosis.

29 Jan 2016

New treatment could stop progression of ALS

Researchers at Oregon State University announced today that they have essentially stopped the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, for nearly two years in one type of mouse model used to study the disease - allowing the mice to approach their normal lifespan.

29 Jan 2016

Education level influences cognitive training outcomes in older adults

The first study to investigate the effects of cognitive training on the cognitive functioning of older adults by education level has found that individuals with fewer than 12 years of schooling benefit more from cognitive training than their more highly educated counterparts.

29 Jan 2016

Researchers develop new painkiller as strong as morphine but not addictive

Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology.

29 Jan 2016

New computational techniques could help researchers pinpoint anatomical source of seizures

For the third of all epilepsy patients who don't respond to medication, an alternative is to locate the small cluster of neurons that act as the seed of a seizure's aberrant electrical activity and surgically remove it. Unfortunately, such surgeries often fail to bring any relief. The ability to reliably pinpoint the anatomical source of seizures, different for each patient, remains elusive.

29 Jan 2016

New SBP research may lead to novel approach to treat heart failure

More than 5 million people in the United States suffer from heart failure, according to the American Heart Association. Less than half of those with heart failure live five years after diagnosis.

29 Jan 2016

Study could open door for new treatment targets to help Parkinson's disease patients walk more easily

Two secrets of one of the brain's most enigmatic regions have finally been revealed. In a pair of new studies, scientists from the Gladstone Institutes have discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson's disease.

29 Jan 2016

Scientists trace one of the causes of ischemia renal failure

Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe. It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia.

29 Jan 2016

LMU researchers reveal how crystalline deposits induce cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now elucidated how the insoluble deposits induce cell death.

29 Jan 2016

Anticholinergic medications may not be best option for dementia patients in rehab facility

During rehabilitation following an acute hospital stay, medications that block neurotransmitters may be overprescribed to older patients suffering from delirium superimposed on dementia, according to health researchers.

29 Jan 2016

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

The first clinical trial to move forward as part of the Van Andel Research Institute-Stand Up To Cancer (VARI-SU2C) Epigenetics Dream Team will target metastatic colorectal cancer, the second leading cause of cancer deaths among men and women combined in the U.S.

29 Jan 2016

Mutation or amplification of HER2 gene may lead to lung cancer

A joint study by University of Colorado Cancer Center and Memorial Sloan Kettering Cancer Center published in the Journal of Thoracic Oncology shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene.

29 Jan 2016

Study finds ethnic differences in coronary heart disease risk within diverse population

In a study of more than 1.3 million Kaiser Permanente members in Northern California that stretched over 10 years, researchers found that blacks, Latinos and Asians generally had lower risk of coronary heart disease compared to whites.

29 Jan 2016

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

A new blood clotting analysis system designed in Japan makes it easier to determine the effects of taking one or more antithrombotic (anti-clotting) drugs.

29 Jan 2016

Scientists discover epigenetic switch linked to obesity

It is well known that a predisposition to adiposity lies in our genes. A new study by researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg now shows that it is also crucial how these genes are regulated. The scientists led by Andrew Pospisilik discovered a novel regulatory, epigenetic switch, which causes individuals with identical genetic material, such as monozygotic twins, to either be lean or obese.

29 Jan 2016

Medical Condition News

Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Adhering to certain diet may help postpone need for dialysis in CKD patients

Weight loss programs that provide healthy fats have similar impacts on pound-shedding

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Access for new melanoma treatment remains uncertain for patients despite UK launch

UCLA researchers find protein combination that could improve clinical bone restoration

New treatment could stop progression of ALS

Education level influences cognitive training outcomes in older adults

Researchers develop new painkiller as strong as morphine but not addictive

New computational techniques could help researchers pinpoint anatomical source of seizures

New SBP research may lead to novel approach to treat heart failure

Study could open door for new treatment targets to help Parkinson's disease patients walk more easily

Scientists trace one of the causes of ischemia renal failure

LMU researchers reveal how crystalline deposits induce cell death

Anticholinergic medications may not be best option for dementia patients in rehab facility

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

Mutation or amplification of HER2 gene may lead to lung cancer

Study finds ethnic differences in coronary heart disease risk within diverse population

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

Scientists discover epigenetic switch linked to obesity

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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