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Viking submits IND application to FDA to conduct VK2809 Phase 2 study in patients with LDL-C and fatty liver disease

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration to conduct a Phase 2 study of VK2809 in patients with hypercholesterolemia and fatty liver disease.

17 Nov 2015

Mylan announces U.S. launch of generic AXERT tablets

Mylan N.V. today announced the U.S. launch of Almotriptan Tablets USP, 6.25 mg and 12.5 mg, the generic version of Janssen Pharmaceutical's AXERT.

17 Nov 2015

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

People diagnosed with schizophrenia who are prone to hallucinations are likely to have structural differences in a key region of the brain compared to both healthy individuals and people diagnosed with schizophrenia who do not hallucinate, according to research published today.

17 Nov 2015

AstraZeneca announces FDA approval of TAGRISSO (AZD9291) for treatment of lung cancer patients

AstraZeneca today announced that the US Food and Drug Administration has approved TAGRISSO (AZD9291) 80mg once-daily tablets for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC), as detected by an FDA-approved test, who have progressed on or after EGFR tyrosine kinase inhibitor (TKI) therapy.

17 Nov 2015

Researchers find ranibizumab drug as effective alternative to laser therapy for treating diabetic retinopathy

In a randomized clinical trial of more than 300 participants, researchers from Johns Hopkins and elsewhere have found that ranibizumab — a drug most commonly used to treat retinal swelling in people with diabetes — is an effective alternative to laser therapy for treating the most severe, potentially blinding form of diabetic retinal disease. Results of the government-sponsored study also show that the drug therapy carries fewer side effects than the currently used laser treatment.

17 Nov 2015

Myriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV events in diabetes patients

Myriad RBM, a wholly-owned subsidiary of Myriad Genetics, Inc., today announced that its DiscoveryMAP platform successfully identified combinations of 15 protein biomarkers associated with cardiovascular (CV) events or death in people with pre-diabetes or early type 2 diabetes, according to a study published by the journal Circulation.

17 Nov 2015

Study reveals why colorectal cancer still returns in some patients after treatment

Cetuximab, marketed as Erbitux, is one of the key therapies for metastatic colorectal cancer. Yet the cancer still returns in some patients, shortening overall survival.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

TTUHSC nephrologists to help find new treatment for lupus nephritis

Nephrologists at Texas Tech University Health Science Center El Paso have been invited to participate in a national consortium that's investigating the key causes of lupus nephritis -- an autoimmune disease that can cause kidney failure.

17 Nov 2015

New approach helps Group Health to increase rates of lifesaving screening for colon cancer

Mailing yearly stool kits--an alternative to the often-dreaded colonoscopy--has helped Group Health to boost rates of lifesaving screening for colon cancer, according to new research from Group Health Research Institute.

17 Nov 2015

Scientists show how absence of microbiota has remarkable effect against obesity

In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning of our organs. In particular, microbiota has also an impact on the way calories are absorbed and how fat cells develop.

17 Nov 2015

Researchers identify molecular patterns that dominate gene expression in the human brain

The human brain may be the most complex piece of organized matter in the known universe, but Allen Institute researchers have begun to unravel the genetic code underlying its function. Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

Overweight men also experience interpersonal discrimination just like overweight women

Men who are overweight are just as likely as overweight women to experience interpersonal discrimination when applying for a job or shopping at retail stores, according to new research from Rice University and the University of North Carolina, Charlotte.

17 Nov 2015

Researchers identify new target for novel immune-oncology treatments

By studying a type of immune cells, a team of researchers at the IRCM led by André Veillette, MD, identified the mechanism of action for a new target for novel immune-oncology treatments. Their discovery is published today in the print edition of the scientific journal the Journal of Experimental Medicine.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

17 Nov 2015

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

The International Association for the Study of Lung Cancer commends the U.S. Food and Drug Administration's (FDA) decision to grant accelerated approval for osimertinib (Tagrisso), an oral medication for advanced non-small cell lung cancer (NSCLC) patients with a specific epidermal growth factor receptor (EGFR) mutation (T790M) and following progression after previous EGFR inhibitor therapies.

17 Nov 2015

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Researchers at the University of Arizona have invented a device that for the first time allows neurosurgeons, who use microscopes extensively while operating, to see blood flowing inside vessels and more clearly distinguish cancerous from healthy tissue under the microscope.

17 Nov 2015

Health care costs for Alzheimer's disease patients increase a year before diagnosis

The health care costs of patients diagnosed with Alzheimer's disease (AD) start to increase already one year before the diagnosis, shows a new study from the University of Eastern Finland.

17 Nov 2015

Medical Condition News

Viking submits IND application to FDA to conduct VK2809 Phase 2 study in patients with LDL-C and fatty liver disease

Mylan announces U.S. launch of generic AXERT tablets

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

AstraZeneca announces FDA approval of TAGRISSO (AZD9291) for treatment of lung cancer patients

Researchers find ranibizumab drug as effective alternative to laser therapy for treating diabetic retinopathy

Myriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV events in diabetes patients

Study reveals why colorectal cancer still returns in some patients after treatment

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

TTUHSC nephrologists to help find new treatment for lupus nephritis

New approach helps Group Health to increase rates of lifesaving screening for colon cancer

Scientists show how absence of microbiota has remarkable effect against obesity

Researchers identify molecular patterns that dominate gene expression in the human brain

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Overweight men also experience interpersonal discrimination just like overweight women

Researchers identify new target for novel immune-oncology treatments

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Health care costs for Alzheimer's disease patients increase a year before diagnosis

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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