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New study identifies molecular mechanism that prevents immunotherapy drugs from killing off cancer

Immunotherapy treatments have proven wildly successful in treating some patients with cancer. But despite this success, the majority of patients do not respond to the treatments.

27 Oct 2015

Research focuses on understanding racial, ethnic disparities in colon cancer outcomes

Blase Polite, MD, has expertise in the treatment of gastrointestinal malignancies, with a particular focus on colon, rectal, and anal cancers, and neuroendocrine (carcinoid) tumors.

27 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Researchers develop multiplexed screening approach to study cancer development in mice

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their cancer-causing roles and determining which combinations of genes cooperate to cause liver cancer.

27 Oct 2015

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Washington State University researchers have developed a unique, tiny protein cage to deliver nasty chemotherapy chemicals directly to cancer cells. Direct delivery could improve treatment and lessen what can be horrendous side effects from toxic drugs.

27 Oct 2015

Many young women not receiving adequate counseling on heart disease

Only half of younger heart attack patients believed that they were at risk before the onset of an attack, and even fewer discussed health risks with their doctors, according to Yale School of Public Health researchers. The findings were more pronounced among women than men.

27 Oct 2015

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Medical professionals know that when a spouse dies, the surviving partner is at increased risk of suffering early mortality - but they don't entirely understand why. A new Rice University professor has received a $3.765 million R01 grant from the National Institutes of Health to embark on a five-year study of the connection between psychological and physiological responses to such extraordinary stress.

27 Oct 2015

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Massachusetts General Hospital investigators have discovered a mechanism behind the spread of neurofibrillary tangles - one of the two hallmarks of Alzheimer's disease - through the brains of affected individuals.

27 Oct 2015

Scientists decode central signal switch associated with epileptic seizures

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.

27 Oct 2015

Study: Reduction in Amazon deforestation improves air quality, prevents premature deaths

Because of decreasing deforestation and emissions from forest fires in the Amazon over the past ten years, the amount of particulate matter (aerosols), ozone, carbon monoxide, nitrogen oxide and other atmospheric pollutants released by burning biomass has fallen by 30% on average during the dry season in southern Brazil, Paraguay, northern Bolivia and Argentina.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

The immunosuppressant sirolimus is an effective and safe steroid-sparing therapy for children and young adults with highly treatment-resistant autoimmune blood conditions, according to a study published online today in Blood, the Journal of the American Society of Hematology.

27 Oct 2015

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists.

27 Oct 2015

Lewy Body Composite Risk Score detects LBD and Parkinson's disease dementia in three minutes

Although Lewy Body disease (LBD) is the second-most-common degenerative disease after Alzheimer's disease, it's not exactly a household name. It affects more than 1.3 million Americans, is poorly recognized, and diagnosis is often significantly delayed. Patients with LBD simultaneously experience losses in cognitive function, mobility and behavior.

27 Oct 2015

Low-weight, high-repetition resistance training increases bone density in adults

A new research study published in The Journal of Sports Medicine and Physical Fitness finds that low-weight, high-repetition resistance training increases bone mineral density in adults, challenging assumptions that heavy weight-training is required to build bone mineral density. Participants who completed the study experienced up to 8 percent bone mineral density increases in the legs, pelvis, arms and spine.

27 Oct 2015

Advanced pancreatic cancer patients now have access to new FDA-approved drug, Onivyde

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute.

27 Oct 2015

Noninvasive CT scans far better than stress tests at spotting clogged arteries

Results of a head-to-head comparison study led by Johns Hopkins researchers show that noninvasive CT scans of the heart's vessels are far better at spotting clogged arteries that can trigger a heart attack than the commonly prescribed exercise stress that most patients with chest pain undergo.

27 Oct 2015

Research finding could lead to new treatment to promote brain repair, functional recovery after stroke

UCLA researchers have identified a molecule that, after a stroke, signals brain tissue to form new connections to compensate for the damage and initiate repairs to the brain.

27 Oct 2015

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Mast Therapeutics, Inc., a clinical-stage biopharmaceutical company leveraging its molecular adhesion and sealant technology (MAST) platform to develop novel therapies for sickle cell disease, heart failure, and stroke, announced that it has initiated its Phase 2 study of vepoloxamer for the treatment of patients with chronic heart failure.

26 Oct 2015

Heart disease becomes the major killer of women in Norway

More research is carried out on breast cancer than on women's heart attack. Even though heart attack kills more women.

26 Oct 2015

Medical Condition News

New study identifies molecular mechanism that prevents immunotherapy drugs from killing off cancer

Research focuses on understanding racial, ethnic disparities in colon cancer outcomes

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Researchers develop multiplexed screening approach to study cancer development in mice

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Many young women not receiving adequate counseling on heart disease

New Rice University study explores connections between fatal bereavement and cardiovascular risk

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Scientists decode central signal switch associated with epileptic seizures

Study: Reduction in Amazon deforestation improves air quality, prevents premature deaths

New drug combination may be effective against malignant melanoma

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

Lewy Body Composite Risk Score detects LBD and Parkinson's disease dementia in three minutes

Low-weight, high-repetition resistance training increases bone density in adults

Advanced pancreatic cancer patients now have access to new FDA-approved drug, Onivyde

Noninvasive CT scans far better than stress tests at spotting clogged arteries

Research finding could lead to new treatment to promote brain repair, functional recovery after stroke

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Heart disease becomes the major killer of women in Norway

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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