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New heart failure drug may increase patients' risk of Alzheimer's disease, macular degeneration

Patients with mild heart failure stand to benefit from a new drug that can halt the progression of their disease and reduce their risk of cardiovascular-related death. But the drug -- a tablet that combines the agents valsartan and sacubitril, sold under the trade name Entresto by drugmaker Novartis -- may be too good to be true, according to Arthur M. Feldman, MD, PhD, Executive Dean of the Lewis Katz School of Medicine at Temple University, Chief Academic Officer of the Temple University Health System, and Laura H. Carnell Professor of Medicine at LKSOM.

10 Dec 2015

Human heart can fully recover after massive damage

The scientists report the case of a newborn that had suffered a massive heart attack in the first hours of life. It was caused by a blockage in a vital coronary vessel. "The baby's heart was severely damaged. Astonishingly, the baby recovered very quickly," said Bernhard Haubner, a cardiologist and researcher, and his colleague, Johanna Schneider, in an article just published in the journal "Circulation Research".

10 Dec 2015

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) differ in their efficacy and safety profiles, according to new research by the University of Leicester.

10 Dec 2015

WHO launches new comprehensive analysis of global health trends

The World Health Organization (WHO) today launched a new comprehensive analysis of global health trends since 2000 and an assessment of the challenges for the next 15 years.

10 Dec 2015

Renowned experts, Nobel laureates to convene at Toulouse Onco Week to discuss latest advances in oncology

The first Toulouse Onco Week (TOW) is due to take place from 3 to 6 February 2016 at the Pierre Baudis Congess Center, Toulouse, France. This unique event will be focused on the international fight against cancer by bringing together stakeholders from around the world and presenting the latest global innovations in oncology.

10 Dec 2015

Two UK studies reveal apparent increase in healthy ageing, less severe disability

Two studies conducted 20 years apart in England reveal an apparent increase in healthy ageing, or years lived healthily, reflecting less cognitive impairment; and an increase in the proportion of life lived healthily, through a larger proportion of years lived with disability but less rather than more severe disability.

10 Dec 2015

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Boehringer Ingelheim announced today that the first person has been enrolled in the SENSCIS (Safety and Efficacy ofNintedanib in Systemic SClerosIS) study.

10 Dec 2015

Left behind rural children in China at increased risk for obesity

Some 61 million rural children left behind by parents moving to China's booming urban centres are at risk from increased fat and reduced protein in their diets, research from The University of Manchester, published in Public Health Nutrition suggests.

10 Dec 2015

VNS technology could help improve lives of people recovering from stroke

A new study involving UT Dallas researchers shows that vagus nerve stimulation (VNS) technology could help improve the lives of hundreds of thousands of people who suffer weakness and paralysis caused by strokes.

10 Dec 2015

Cognitive behavioral therapy can be equally effective as second generation antidepressant for depression

Major depressive disorder affects more than 32 million Americans, and their first stop for treatment is often their primary care provider. A recent evidence review of several alternatives to medication found that using cognitive behavioral therapy as the first treatment for depression can be equally effective as using a second generation antidepressant.

10 Dec 2015

Scientists discover that blocking RANKL protein stops osteosarcoma

Scientists at Princess Margaret Cancer Centre have discovered that blocking the master regulator of bone renewal stops osteosarcoma - the most common primary bone cancer in children and teens, and the malignant disease that was fatal for Canadian icon Terry Fox.

10 Dec 2015

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities result in a final common pathway of vasoconstriction, micro thrombosis and vascular remodelling.

10 Dec 2015

Researchers use mathematical models to study brain cells essential for correct functioning of neurons

Applying mathematical models used for studying the galaxies or interactions between elementary particles, researchers at the Institute of Neuroscience of the Universitat Autònoma de Barcelona, in collaboration with Massachusetts General Hospital, Boston, have analysed the spatial distribution of astrocytes: brain cells that are essential for the correct functioning of neurons.

10 Dec 2015

TET proteins needed to maintain genome instability, say researchers

Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers at the La Jolla Institute for Allergy and Immunology demonstrate that TET proteins collectively constitute a major class of tumor suppressors and are required to maintain genome instability.

9 Dec 2015

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

Considerable racial disparities exist in surgical outcomes for black and Hispanic patients undergoing major cancer and non-cancer surgeries in U.S. hospitals, even among institutions that have already enrolled in a national surgical quality improvement initiative.

9 Dec 2015

New three-drug delivery system shows promise for treatment of metastatic melanoma

Researchers have developed a new three-drug delivery system for cancer treatment, especially metastatic melanoma, the deadliest form of skin cancer - and shown that the system may have particular value with cancers like this that often spread through the lymphatic system.

9 Dec 2015

Older men with sleep-disordered breathing at greater risk of developing atrial fibrillation

Sleep-disordered breathing often predicts the development of atrial fibrillation (AF) in older men, according to U.S. researchers.

9 Dec 2015

UT awarded $1 million USDA grant to combat childhood obesity

One of every three children in Tennessee is overweight, and more than 20 percent of our children are obese. Childhood obesity has been linked to diabetes, high blood pressure, depression and poor academic performance.

9 Dec 2015

Textbook view of the human cell cycle needs to be revised, shows new Danish research

Ground-breaking new Danish research has shown that the current scientific description of the human cell cycle needs to be revised. These findings could also lead to the development of new therapeutic approaches to target an Achilles' heel in different types of cancers.

9 Dec 2015

$Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures$

Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures

A combination of adult stem cells and parathyroid hormone significantly increased new bone formation in laboratory animals and may speed the healing process for human bone fractures caused by osteoporosis, a new study shows.

9 Dec 2015

Medical Condition News

New heart failure drug may increase patients' risk of Alzheimer's disease, macular degeneration

Human heart can fully recover after massive damage

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

WHO launches new comprehensive analysis of global health trends

Renowned experts, Nobel laureates to convene at Toulouse Onco Week to discuss latest advances in oncology

Two UK studies reveal apparent increase in healthy ageing, less severe disability

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Left behind rural children in China at increased risk for obesity

VNS technology could help improve lives of people recovering from stroke

Cognitive behavioral therapy can be equally effective as second generation antidepressant for depression

Scientists discover that blocking RANKL protein stops osteosarcoma

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Researchers use mathematical models to study brain cells essential for correct functioning of neurons

TET proteins needed to maintain genome instability, say researchers

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

New three-drug delivery system shows promise for treatment of metastatic melanoma

Older men with sleep-disordered breathing at greater risk of developing atrial fibrillation

UT awarded $1 million USDA grant to combat childhood obesity

Textbook view of the human cell cycle needs to be revised, shows new Danish research

Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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