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New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood. The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

16 Sep 2015

Winners of Renal Support Network's 13th Annual Essay Contest announced

Now in its 13th year of providing a voice for people who have kidney disease and are passionate about writing, Renal Support Network announces the winners of its 13th Annual Essay Contest.

16 Sep 2015

$Fragility fractures projected to rise dramatically within next three decade$

Fragility fractures projected to rise dramatically within next three decade

Nyon, Switzerland A study from the University of Southampton and Sheffield Medical School in the UK projects a dramatic increase in the burden of fragility fractures within the next three decades.

16 Sep 2015

Research examines effects of antidepressant use on health of mother and child

The use of antidepressants during pregnancy has no long term neurodevelopmental or behavioural effects on the child, however they may be associated with an increased risk of postpartum haemorrhage, suggests the findings from three studies published in BJOG: An International Journal of Obstetrics and Gynaecology (BJOG).

16 Sep 2015

Bionomics’ BNC210 Phase 1 trial for anxiety and depression meets primary endpoint

Bionomics Limited, a biopharmaceutical company focused on the discovery and development of innovative therapeutics for the treatment of diseases of the central nervous system (CNS) and cancer, today reported positive data from the completed Phase 1 multiple ascending dose, placebo controlled clinical trial of BNC210, an orally administered negative allosteric modulator of the alpha-7 nicotinic acetylcholine receptor (alpha-7 receptor) being developed for the treatment of anxiety and depression.

16 Sep 2015

Scientists find how cells adapt to overcome cancer drugs

CANCER RESEARCH UK scientists have found how cells adapt to overcome cancer drugs designed to interfere with their genetic controls, according to a study published today (Wednesday) in Epigenetics and Chromatin.

16 Sep 2015

Precise mouse brain map may provide new insights into brain circuits and origins of mental illnesses

Scientists at Duke University have released a highly detailed model of connections in the mouse brain that could provide generations of neuroscientists new insights into brain circuits and origins of mental illness, such as depression and schizophrenia.

16 Sep 2015

NUS researchers develop new technique to observe nano-bio interactions

Researchers at the National University of Singapore have developed a technique to observe, in real time, how individual blood components interact and modify advanced nanoparticle therapeutics.

16 Sep 2015

Researchers use new synthetic method to prepare potential drug candidates for type 2 diabetes

Aryl alkyl ethers are important structural motifs found in many biologically active compounds. Therefore, stereoselective etherification is a highly important synthetic operation in the preparation of drug candidates.

16 Sep 2015

Fetuses with enlarged ventricles are not ideal candidates for fetal spina bifida surgery

Fetuses with enlarged ventricles--the fluid-filled cavities inside the brain--may be less likely than other fetuses to benefit from surgery in the womb to treat spina bifida, according to a study co-authored by researchers at UCSF Benioff Children's Hospital San Francisco.

16 Sep 2015

USF study shows spleen may be a new target for treating stroke-induced chronic inflammation

Stroke injures the brain, but a new University of South Florida study indicates an abdominal organ that plays a vital role in immune function, the spleen, may be a target for treating stroke-induced chronic inflammation leading to further brain cell death.

16 Sep 2015

AstraZeneca presents safety and efficacy data for ExQW at 51st Annual Meeting of EASD

AstraZeneca today announced new analyses of exenatide once weekly (ExQW) demonstrating a favorable gastrointestinal (GI) tolerability profile, including less frequent upper and lower GI adverse events (AE), compared to shorter-acting glucagon-like peptide-1 receptor agonists (GLP-1RA), exenatide twice daily (ExBID) and liraglutide once daily (LiraQD).

16 Sep 2015

New method may help nurses and doctors quickly identify delirium in hospitalized older adults

Asking just two questions may be able to help nurses and doctors quickly and easily identify delirium in hospitalized older adults, according to health researchers.

16 Sep 2015

PHE-led study shows England has huge opportunity for lowest disease burden, preventive public health

For the first time, a new PHE led study published in The Lancet ranks the diseases and risk factors that cause death and disability in England compared with other high-income countries, revealing the nation’s potential to have the lowest total disease burden (years of life lost to death and lived with disability) in the world.

16 Sep 2015

QuartrBack project creates smart emergency scheme for people suffering from dementia

People with dementia exhibit many far-reaching changes of conduct. Embarrassment, fear, and reduced orientation ability decrease their degree of independence and social inclusion. The QuartrBack project coordinated by the Evangelische Heimstiftung now combines volunteer work with technologies for location, monitoring, information, and professional care.

16 Sep 2015

AMD Alliance hosts webinar to promote awareness and knowledge about macular disease

14 – 20 September marks global AMD Awareness Week 2015. Age related macular degeneration (AMD) is a progressive eye disease which is the leading cause of blindness in over 50s globally.

16 Sep 2015

Yoga improves physical, mental wellbeing of people living with common forms of arthritis

A randomized trial of people with two common forms of arthritis has found that yoga can be safe and effective for people with arthritis. Johns Hopkins researchers report that 8 weeks of yoga classes improved the physical and mental wellbeing of people with two common forms of arthritis, knee osteoarthritis and rheumatoid arthritis.

16 Sep 2015

Healthy diet and exercise can protect against AMD

People with a genetic predisposition for age-related macular degeneration (AMD) significantly increased their odds of developing the blinding eye disorder if they had a history of heavy smoking and consistently did not exercise or eat enough fruits and vegetables, according to an observational study of women funded by the National Eye Institute, part of the National Institutes of Health.

16 Sep 2015

Researchers receive NIH grant to test novel drug therapy for Alzheimer's dementia

Johns Hopkins University researchers have received an estimated $7.5 million National Institutes of Health grant to clinically test what would be the first treatment to prevent or delay the onset of Alzheimer's dementia.

16 Sep 2015

New computational model may help overcome misalignment of U.S. biomedical research resources

A new computational model developed by scientists from the University of Chicago could help improve the allocation of U.S. biomedical research resources.

16 Sep 2015

Medical Condition News

New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Winners of Renal Support Network's 13th Annual Essay Contest announced

Fragility fractures projected to rise dramatically within next three decade

Research examines effects of antidepressant use on health of mother and child

Bionomics’ BNC210 Phase 1 trial for anxiety and depression meets primary endpoint

Scientists find how cells adapt to overcome cancer drugs

Precise mouse brain map may provide new insights into brain circuits and origins of mental illnesses

NUS researchers develop new technique to observe nano-bio interactions

Researchers use new synthetic method to prepare potential drug candidates for type 2 diabetes

Fetuses with enlarged ventricles are not ideal candidates for fetal spina bifida surgery

USF study shows spleen may be a new target for treating stroke-induced chronic inflammation

AstraZeneca presents safety and efficacy data for ExQW at 51st Annual Meeting of EASD

New method may help nurses and doctors quickly identify delirium in hospitalized older adults

PHE-led study shows England has huge opportunity for lowest disease burden, preventive public health

QuartrBack project creates smart emergency scheme for people suffering from dementia

AMD Alliance hosts webinar to promote awareness and knowledge about macular disease

Yoga improves physical, mental wellbeing of people living with common forms of arthritis

Healthy diet and exercise can protect against AMD

Researchers receive NIH grant to test novel drug therapy for Alzheimer's dementia

New computational model may help overcome misalignment of U.S. biomedical research resources

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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