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TET proteins needed to maintain genome instability, say researchers

Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers at the La Jolla Institute for Allergy and Immunology demonstrate that TET proteins collectively constitute a major class of tumor suppressors and are required to maintain genome instability.

9 Dec 2015

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

Considerable racial disparities exist in surgical outcomes for black and Hispanic patients undergoing major cancer and non-cancer surgeries in U.S. hospitals, even among institutions that have already enrolled in a national surgical quality improvement initiative.

9 Dec 2015

New three-drug delivery system shows promise for treatment of metastatic melanoma

Researchers have developed a new three-drug delivery system for cancer treatment, especially metastatic melanoma, the deadliest form of skin cancer - and shown that the system may have particular value with cancers like this that often spread through the lymphatic system.

9 Dec 2015

Older men with sleep-disordered breathing at greater risk of developing atrial fibrillation

Sleep-disordered breathing often predicts the development of atrial fibrillation (AF) in older men, according to U.S. researchers.

9 Dec 2015

UT awarded $1 million USDA grant to combat childhood obesity

One of every three children in Tennessee is overweight, and more than 20 percent of our children are obese. Childhood obesity has been linked to diabetes, high blood pressure, depression and poor academic performance.

9 Dec 2015

Textbook view of the human cell cycle needs to be revised, shows new Danish research

Ground-breaking new Danish research has shown that the current scientific description of the human cell cycle needs to be revised. These findings could also lead to the development of new therapeutic approaches to target an Achilles' heel in different types of cancers.

9 Dec 2015

$Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures$

Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures

A combination of adult stem cells and parathyroid hormone significantly increased new bone formation in laboratory animals and may speed the healing process for human bone fractures caused by osteoporosis, a new study shows.

9 Dec 2015

Ground breaking technology could revolutionise cancer diagnosis

A University of Warwick computer scientist is working with technology that could revolutionise how some cancers are diagnosed.

9 Dec 2015

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

In the majority of cases, hip x-rays are not reliable for diagnosing hip osteoarthritis (OA), and can delay the treatment of this debilitating disease.

9 Dec 2015

Tetra begins human Phase 1 safety trials of BPN14770

Tetra Discovery Partners today announced that the company has initiated human Phase 1 safety trials of its lead compound BPN14770, which Tetra is developing as a potential treatment to both improve memory and slow the progression of Alzheimer's disease.

9 Dec 2015

Research examines ketone esters to combat hyperbaric oxygen toxicity in Navy divers

For the first time, ketone esters-oral supplements useful in epilepsy treatment-are being studied to fight seizures caused by hyperbaric oxygen toxicity, a life-threatening byproduct of breathing too much oxygen that impacts deep-water divers.

9 Dec 2015

Flagship launches Rubius to develop functionalized red blood cells for treatment of serious diseases

Flagship Ventures, a leading innovation and venture firm focused on healthcare and sustainability, announced it has launched Rubius Therapeutics, to develop functionalized red blood cells for the treatment of autoimmune conditions, metabolic diseases, cancer, and other serious diseases.

9 Dec 2015

Economic and racial barriers impact treatment of moderate to severe psoriasis

In the first known study to examine the prevalence and treatment of psoriasis in older Americans, experts from the Perelman School of Medicine at the University of Pennsylvania have found that black patients receiving Medicare are less likely to receive biologic therapies -medications derived from human or animal cells or tissues - for the treatment of moderate to severe psoriasis than white patients.

9 Dec 2015

Surgery and manual physical therapies similarly effective in improving pain for CTS patients

Results of a randomized clinical trial, published in The Journal of Pain, showed that surgery and manual physical therapies were similarly effective in improving pain and function for patients with carpal tunnel syndrome (CTS).

9 Dec 2015

Dietary sugar may help to treat melanoma

New research from scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) suggests that a rare sugar found in seaweed, mushrooms, seeds and other foods may be able to help treat skin cancer.

9 Dec 2015

Biotypes can identify distinct subgroups of psychosis

Three biomarker-based categories, called biotypes, outperformed traditional diagnoses, such as schizophrenia and bipolar disorder with psychosis, in sorting psychosis cases into distinct subgroups on the basis of brain biology, report researchers funded by the National Institutes of Health.

9 Dec 2015

Adverse environmental changes present potential health hazards to eyes

Another reason to worry about climate change: Expanding areas of arid land, air pollution, and greater exposure to ultraviolet (UV) radiation all present potential health hazards to your eyes, according to Sheila West, Ph.D., vice chair for research at the Wilmer Eye Institute, Johns Hopkins University.

9 Dec 2015

Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

In a study released online today in The BMJ, researchers from Mayo Clinic report a national trend toward overtesting glycated hemoglobin (HbA1C) levels in adult patients with Type 2 diabetes.

9 Dec 2015

New article reveals link between poor kidney function, worse outcomes after heart surgery

Poor kidney function prior to heart surgery can lead to worse outcomes, higher surgical costs, and a longer hospital stay, according to an article posted online today by The Annals of Thoracic Surgery.

9 Dec 2015

Arterial grafts provide better outcomes than venous grafts in heart bypass surgery patients

The Society of Thoracic Surgeons has released new clinical practice guidelines that recommend expanding the use of arteries from the chest and forearm rather than using veins from the leg when performing coronary artery bypass grafting (CABG) surgery in certain patients. The guidelines, posted online today, will appear in the February 2016 issue of The Annals of Thoracic Surgery.

9 Dec 2015

Medical Condition News

TET proteins needed to maintain genome instability, say researchers

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

New three-drug delivery system shows promise for treatment of metastatic melanoma

Older men with sleep-disordered breathing at greater risk of developing atrial fibrillation

UT awarded $1 million USDA grant to combat childhood obesity

Textbook view of the human cell cycle needs to be revised, shows new Danish research

Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures

Ground breaking technology could revolutionise cancer diagnosis

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

Tetra begins human Phase 1 safety trials of BPN14770

Research examines ketone esters to combat hyperbaric oxygen toxicity in Navy divers

Flagship launches Rubius to develop functionalized red blood cells for treatment of serious diseases

Economic and racial barriers impact treatment of moderate to severe psoriasis

Surgery and manual physical therapies similarly effective in improving pain for CTS patients

Dietary sugar may help to treat melanoma

Biotypes can identify distinct subgroups of psychosis

Adverse environmental changes present potential health hazards to eyes

Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

New article reveals link between poor kidney function, worse outcomes after heart surgery

Arterial grafts provide better outcomes than venous grafts in heart bypass surgery patients

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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