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Caltech researchers identify gene that causes severe insomnia when overactivated

Caltech biologists have performed the first large-scale screening in a vertebrate animal for genes that regulate sleep, and have identified a gene that when overactivated causes severe insomnia. Expression of the gene, neuromedin U (Nmu), also seems to serve as nature's stimulant--fish lacking the gene take longer to wake up in the morning and are less active during the day.

18 Feb 2016

Autoantibodies can potentially detect lung cancer at early stage

Preliminary research has identified autoantibodies, immune proteins found in the blood specific for one's own proteins, that can potentially detect lung cancer early by distinguishing between smokers with or without lung cancer and also discriminate between lung cancer and low-dose computed tomography (LDCT) detected non-cancerous lung lesions.

18 Feb 2016

Pioglitazone drug may prevent recurrent stroke and heart attacks

Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes.

18 Feb 2016

Eating one portion of fish a week helps reduce dementia risk

Eating at least one portion of fish per week helps to reduce a person's risk of developing Alzheimer's disease and dementia-related illnesses. This was evidenced by international research conducted at the Rush University Medical Center in Chicago and published in the Journal of American Medical Association (JAMA).

18 Feb 2016

Researchers reveal how brain-specific microRNA plays key role in causing abnormal brain development

Autism Spectrum Disorders (ASDs) are a group of highly inheritable behavioural disorders that pose major personal and public health concerns. Patients with ASDs have mild to severe communication difficulties, repetitive behaviour and social challenges. Such disorders significantly challenge an individual's ability to conduct daily activities and function normally in society. Currently there are very few medication options that effectively treat ASDs.

17 Feb 2016

Graphic anti-smoking images can warn smokers about cigarettes' health consequences

Viewing graphic anti-smoking images on cigarette packs triggers activity in brain areas involved in emotion, decision-making and memory as observed via brain scans.

17 Feb 2016

Studies explore causative factor of hypertension in younger, obese men and women

There's no doubt estrogen plays a big role in the differences between males and females, and now researchers want to know if it also helps explain emerging sex differences in what makes younger, obese men and women hypertensive.

17 Feb 2016

ACC, AHA support implementation of proposed cardiovascular measures, with reservations

Quality measures announced today by the Core Quality Measures Collaborative represent a step forward in reducing paperwork and confusion while also allowing providers to focus on measures that impact patient outcomes, the American College of Cardiology (ACC) and the American Heart Association (AHA) said in support of implementation of the proposed cardiovascular measures. But the groups expressed reservations about blood pressure targets included in the measures.

17 Feb 2016

Special issue explores trauma and adversity among migrating populations

A timely collection of papers on trauma and adversity among migrating populations has been published today in the European Journal of Psychotraumatology.

17 Feb 2016

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

In patients with coronary heart disease requiring a stent implantation, the benefit of treatment with antibody-coated drug-eluting stents (ABC-DES) versus drug-eluting stents without antibody coating (DES) is still unclear.

17 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

A study led by scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key player contributing to the maintenance of hematopoietic stem cells (HSCs), blood cell precursors which have the ability to become any type of blood cell in the body.

17 Feb 2016

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Fast metastasis and resistance to treatment are characteristic of aggressive types of cancer such as pancreatic cancer and certain kinds of breast cancer. They are also the main causes of cancer-related death, as there is currently no specific treatment available that is able to stop tumours spreading throughout the whole body. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have recently made a discovery that could change this.

17 Feb 2016

Wistar researchers find potential way for using STAT3 inhibitors to stop cancer progression

Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced by scientists researching inhibitors of signal transducer and activator of transcription (STAT3), a protein that controls transcription by the STAT3 gene.

17 Feb 2016

High salt and sodium intake persists in China: Study

Yongning Wu, Ph.D., of the China National Centre for Food Safety Risk Assessment, Beijing, China, and colleagues compared salt and sodium consumption in China in 2000 with 2009-2012. The study appears in the February 16 issue of JAMA.

17 Feb 2016

First-of-its-kind project focuses on farming communities and dementia

Dementia is a growing health problem, with an anticipated increase in the number of cases in the UK of 156 per cent between now and 2051, according to statistics from the Alzheimer's Society.

17 Feb 2016

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Potsdam-Rehbruecke - Like sucrose (table sugar), the natural disaccharide isomaltulose (PalatinoseTM) consists of glucose and fructose, but it is apparently more suitable for people with type 2 diabetes with regard to regulating blood glucose levels.

17 Feb 2016

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

A small peptide dubbed TAxI is living up to its name. Recent studies show it to be an effective vehicle for shuttling functional proteins, such as active enzymes, into the spinal cord after a muscle injection.

17 Feb 2016

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

With every heart attack, billions of cardiomyocytes, the contracting heart muscle cells that make the heart pump time after time over a lifetime, are lost which can lead to heart failure or injury. Stem cell-based replacement strategies could open new and much needed therapeutic avenues.

17 Feb 2016

Green tea compound has high potential as treatment for rheumatoid arthritis

Researchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, inflammation and tissue damage caused by rheumatoid arthritis.

17 Feb 2016

Medical Condition News

Caltech researchers identify gene that causes severe insomnia when overactivated

Autoantibodies can potentially detect lung cancer at early stage

Pioglitazone drug may prevent recurrent stroke and heart attacks

Eating one portion of fish a week helps reduce dementia risk

Researchers reveal how brain-specific microRNA plays key role in causing abnormal brain development

Graphic anti-smoking images can warn smokers about cigarettes' health consequences

Studies explore causative factor of hypertension in younger, obese men and women

ACC, AHA support implementation of proposed cardiovascular measures, with reservations

Special issue explores trauma and adversity among migrating populations

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

New optogenetic technology could turn on immune cells to attack melanoma tumors

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Wistar researchers find potential way for using STAT3 inhibitors to stop cancer progression

High salt and sodium intake persists in China: Study

First-of-its-kind project focuses on farming communities and dementia

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

Green tea compound has high potential as treatment for rheumatoid arthritis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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