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University of Bristol-led study could provide new target for treating neurological disorders

Findings, published today [15 Jul] in Nature Communications, reveal the extent a mutation associated with autism and epilepsy plays in impairing a biochemical process in the brain. The study, led by University of Bristol researchers, could provide a new target for treating neurological disorders.

16 Jul 2015

Researchers identify gene that underlies thinking skills

An international team of researchers, including investigators from the University of Mississippi Medical Center, has identified a gene that underlies healthy information processing -- a first step on a complicated road to understand cognitive aging and age-related diseases, such as Alzheimer's disease.

16 Jul 2015

Older adults can boost brain function by raising their fitness level

New research conducted at the University of Kansas Medical Center indicates that older adults can improve brain function by raising their fitness level.

16 Jul 2015

U of T researchers discover new details about key gene involved in ALS

A University of Toronto research team has discovered new details about a key gene involved in ALS, perhaps humanity's most puzzling, intractable disease.

16 Jul 2015

Salk researchers move one step closer to making cures for genetic diseases a reality

Healthy brain, muscle, eye and heart cells would improve the lives of tens of thousands of people around the world with debilitating mitochondrial diseases. Now, researchers at the Salk Institute have gotten one step closer to making such cures a reality: they've turned cells from patients into healthy, mutation-free stem cells that can then become any cell type.

16 Jul 2015

Two chemical compounds effectively inhibit growth of brain cancer cells and breast tumors

Researchers have discovered two chemical compounds that effectively stop the growth of brain cancer cells and breast tumors, opening the way for potential new drugs to be developed.

16 Jul 2015

Researchers identify DPP9 enzyme that can regulate growth, movement of liver cancer cells

Researchers at the Centenary Institute in Sydney have uncovered new information about an enzyme called DPP9 that they believe to be a potential therapeutic target for limiting tumour growth and its ability to spread to and in the liver.

15 Jul 2015

Futura Medical develops new generation of topical pain relief

Futura Medical has developed a "new generation" of topical pain relief with two products that target more active ingredients directly to the point of pain. The new products have the potential to transform the pain relief market, according to chief executive James Barder.

15 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury.

15 Jul 2015

Scientists propose new spinal cord stimulation strategy to activate motor neurons

Patients, doctors and researchers look with great expectations to epidural electrostimulation, a medical technique that could alleviate the condition of subjects affected by paralysis due to spinal cord injury. Although still relatively rudimentary, the technique is constantly being improved thanks to research.

15 Jul 2015

New review article explains link between PTSD and increased cardiovascular disease risk

A growing number of patient studies show that people who suffered post-traumatic stress disorder (PTSD) are at a higher risk of developing cardiovascular diseases, including stroke and heart attack. A new review article in American Journal of Physiology—Regulatory, Integrative and Comparative Physiology examines the recent scientific literature to explain how the two are linked.

15 Jul 2015

Updated guidelines released for treatment of idiopathic pulmonary fibrosis

Updated guidelines on the treatment of idiopathic pulmonary fibrosis (IPF) have been released by an international group of leading respiratory societies, The new guidelines, issued by the American Thoracic Society, the European Respiratory Society, the Japanese Respiratory Society, and the Latin American Thoracic Association, were published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

15 Jul 2015

Diabetes drug metformin can also treat portal hypertension

The diabetes drug metformin continues to expand beyond its treatment for type 2 diabetes. In addition to its potential use in treating age-related health problems, metformin can treat portal hypertension—high blood pressure in the liver resulting from cirrhosis, according to a new study in American Journal of Physiology—Gastrointestinal and Liver Physiology.

15 Jul 2015

Wayne State researcher receives $1.9 million grant to improve EPCs-based cell therapy for vascular diseases

Chunying Li, Ph.D., assistant professor in the Wayne State University School of Medicine's Department of Biochemistry and Molecular Biology, has secured his first R01 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to study the role and mechanism of the chemokine receptor CXCR2 in regulating new blood vessel formation, the so-called angiogenesis.

15 Jul 2015

Study examines accuracy, cost-effectiveness of new cholesterol guidelines in identifying increased CVD risk

An examination of the 2013 guidelines for determining statin eligibility, compared to guidelines from 2004, indicates that they are associated with greater accuracy and efficiency in identifying increased risk of cardiovascular disease (CVD) events and presence of subclinical coronary artery disease, particularly in individuals at intermediate risk, according to a study in the July 14 issue of JAMA.

15 Jul 2015

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA.

15 Jul 2015

Highlights from the most recent issue of Epilepsy Currents

The latest issue of Epilepsy Currents is now available featuring expert commentary on abstracts in basic science and clinical topics.

15 Jul 2015

New non-invasive glucose monitoring device could transform lives of people with diabetes

A new laser sensor that monitors blood glucose levels without penetrating the skin could transform the lives of millions of people living with diabetes.

15 Jul 2015

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

Systemic lupus erythematosus (SLE) is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can lead to a variety of symptoms, including inflammation of the kidneys, or nephritis. When researchers transplanted mesenchymal stem cells (MSCs) derived from human bone marrow into mice modeled with SLE, they found that inflammation was reduced and nephritis "attenuated."

15 Jul 2015

Medical Condition News

University of Bristol-led study could provide new target for treating neurological disorders

Researchers identify gene that underlies thinking skills

Older adults can boost brain function by raising their fitness level

U of T researchers discover new details about key gene involved in ALS

Salk researchers move one step closer to making cures for genetic diseases a reality

Two chemical compounds effectively inhibit growth of brain cancer cells and breast tumors

Researchers identify DPP9 enzyme that can regulate growth, movement of liver cancer cells

Futura Medical develops new generation of topical pain relief

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

Scientists propose new spinal cord stimulation strategy to activate motor neurons

New review article explains link between PTSD and increased cardiovascular disease risk

Updated guidelines released for treatment of idiopathic pulmonary fibrosis

Diabetes drug metformin can also treat portal hypertension

Wayne State researcher receives $1.9 million grant to improve EPCs-based cell therapy for vascular diseases

Study examines accuracy, cost-effectiveness of new cholesterol guidelines in identifying increased CVD risk

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Highlights from the most recent issue of Epilepsy Currents

New non-invasive glucose monitoring device could transform lives of people with diabetes

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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