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MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Advanced non-small cell lung cancer (NSCLC) patients have few effective treatment options and low 5-year survival rates. The checkpoint inhibitors MEDI4736 and tremelimumab have both demonstrated acceptable safety and potential efficacy when used as single-agents in several different types of cancer.

29 May 2015

Rapid-deployment plasma protocol helps treat trauma victims faster in the ER

Traumatic injury is the leading cause of death among people under age 45, but if trauma physicians could deliver plasma to these injury victims within minutes of their arrival in the emergency room, more of them would stand a better chance of survival.

29 May 2015

JAK2 inhibitor ruxolitinib shows promise in treating CMML patients

Chronic myelomonocytic leukemia (CMML) is a rare type of myelodysplastic, myeloproliferative neoplasm characterized by increased numbers of peripheral monocytes and less than 20 percent blasts. CMML has few treatment options and patients only survive on average for 12 to 24 months.

29 May 2015

Study: New cases of cancer rising globally, but death rates falling in many countries

New cases of virtually all types of cancer are rising in countries globally - regardless of income - but the death rates from cancer are falling in many countries, according to a new analysis of 28 cancer groups in 188 countries.

29 May 2015

Metformin can reduce risk of open-angle glaucoma in people with diabetes

Taking the medication metformin hydrochloride was associated with reduced risk of developing the sight-threatening disease open-angle glaucoma in people with diabetes, according to a study published online by JAMA Ophthalmology.

29 May 2015

Hearing impairment more prevalent among Hispanic/Latino adults

Hearing impairment was more prevalent among men and older individuals in a study of U.S. Hispanic/Latino adults, according to a report published online by JAMA Otolaryngology-Head and Neck Surgery.

29 May 2015

Boehringer Ingelheim, University of Michigan partner to discover new medicines for diabetic nephropathy

Boehringer Ingelheim and the University of Michigan announce today that they have entered into a research collaboration focused on the discovery of new medicines for patients with diabetic nephropathy.

29 May 2015

Therapy for genetically-caused emphysema slows progression of lung disease

A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.

29 May 2015

New study examines best practices in teaching medical students to better detect skin lesions

Each year, thousands of Canadians are given the news: they have skin cancer. It is the most common form of cancer in Canada and around the world, but if detected early, survival rates are extremely high. According to Liam Rourke, it doesn't happen nearly as often as it could.

29 May 2015

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Sanford-Burnham Medical Research Institute at Lake Nona today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.

29 May 2015

Study shows differences in rates of paracetamol-linked acute liver failure among European countries

A fifty-fold between-country difference in rates of paracetamol-induced acute liver failure that leads to liver transplant (ALFT) has been revealed by a study that compared patient data from seven countries at the request of the European Medicines Agency: France, Greece, Ireland, Italy, Netherlands, Portugal and the UK.

29 May 2015

Impulsive behavior could put you at risk for binge eating

Do you get impulsive when you're upset? If so, this could be putting you at risk for binge eating. According to Kelly Klump, professor of psychology at Michigan State University and senior author, the more impulsive you are, the more likely it is you'll binge eat when experiencing negative feelings.

29 May 2015

Novel discovery offers new insight into why women more likely than men to develop MS

An innocent mistake made by a graduate student in a Northwestern Medicine lab (she accidentally used male mice instead of female mice during an experiment) has led scientists to a novel discovery that offers new insight into why women are more likely than men to develop autoimmune diseases such as multiple sclerosis (MS).

28 May 2015

UB researchers identify mechanisms behind some autistic behaviors, suggest potential targets

Scientists at the University at Buffalo have identified the mechanisms behind a genetic mutation that produces certain autistic behaviors in mice, as well as therapeutic strategies to restore normal behaviors.

28 May 2015

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

A new collaborative study led by researchers at Sanford-Burnham Medical Research Institute, published today in Cell Reports, provides new insight into the molecular changes that lead to resistance to a commonly prescribed group of drugs called BRAF inhibitors.

28 May 2015

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the initiation of CALLISTO, a new comprehensive clinical research program for their novel oral anticoagulant, rivaroxaban, in patients with active cancer. The studies are evaluating the medicine for the prevention and treatment of life-threatening blood clots in patients with a wide range of cancer types.

28 May 2015

People with MS have much greater risk of dying younger compared to people without MS

New research suggests people with multiple sclerosis (MS) may have double the risk of dying early compared to people without MS, with those younger than 59 at a three times higher risk. The study is published in the May 27, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 May 2015

Researchers identify chemical pathway associated with seizures, shorter survival in patients with malignant glioma

Researchers at the University of Alabama at Birmingham have identified a chemical pathway that may be associated with seizures and shorter patient survival in some patients with malignant glioma, the most common and deadly form of brain tumor. In findings published May 27 in Science Translational Medicine, the researchers suggest that a transporter known as SXC is responsible for boosting levels of glutamate in the brains of some glioma patients.

28 May 2015

St. Luke’s, Greater Delaware Valley Chapter of MS Society partner to improve MS care

St. Luke’s Neurology Associates and the Greater Delaware Valley Chapter of the National Multiple Sclerosis Society agreed to a “Partners in MS Care” partnership.

28 May 2015

Clementia Pharmaceuticals commences multi-center study of patients with fibrodysplasia ossificans progressiva

Clementia Pharmaceuticals, Inc. today announced that it has commenced enrollment in the second part (Part B) of its natural history study in patients with fibrodysplasia ossificans progressiva (FOP), a rare, severely disabling congenital myopathy characterized by painful, recurrent episodes of soft tissue swelling (flare-ups) that result in the formation of new, abnormal (heterotopic) bone in muscles, tendons and ligaments.

28 May 2015

Medical Condition News

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Rapid-deployment plasma protocol helps treat trauma victims faster in the ER

JAK2 inhibitor ruxolitinib shows promise in treating CMML patients

Study: New cases of cancer rising globally, but death rates falling in many countries

Metformin can reduce risk of open-angle glaucoma in people with diabetes

Hearing impairment more prevalent among Hispanic/Latino adults

Boehringer Ingelheim, University of Michigan partner to discover new medicines for diabetic nephropathy

Therapy for genetically-caused emphysema slows progression of lung disease

New study examines best practices in teaching medical students to better detect skin lesions

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Study shows differences in rates of paracetamol-linked acute liver failure among European countries

Impulsive behavior could put you at risk for binge eating

Novel discovery offers new insight into why women more likely than men to develop MS

UB researchers identify mechanisms behind some autistic behaviors, suggest potential targets

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

People with MS have much greater risk of dying younger compared to people without MS

Researchers identify chemical pathway associated with seizures, shorter survival in patients with malignant glioma

St. Luke’s, Greater Delaware Valley Chapter of MS Society partner to improve MS care

Clementia Pharmaceuticals commences multi-center study of patients with fibrodysplasia ossificans progressiva

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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