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Omeros reports additional positive data from OMS721 Phase 2 trial for treatment of thrombotic microangiopathies

Omeros Corporation today announced additional positive data in the company's Phase 2 clinical trial of OMS721 for the treatment of thrombotic microangiopathies (TMAs). TMAs are a family of rare, debilitating and life-threatening disorders characterized by excessive thrombi (clots) – aggregations of platelets – in the microcirculation of the body's organs, most commonly the kidney and brain.

18 Aug 2015

Researchers test new non-invasive technique that can accurately detect malignant melanoma

Researchers have developed a new non-invasive technique which can accurately detect malignant melanoma without a biopsy.

18 Aug 2015

First patient enrolled in Phase II trial of ImmunoPulse IL-12 and pembrolizumab combination therapy

OncoSec Medical Incorporated, a company developing DNA-based intratumoral cancer immunotherapies, today announced enrollment of the first patient into the Phase II Investigator Sponsored Trial led by the University of California, San Francisco to assess the anti-tumor activity, safety, and tolerability of the combination of OncoSec's investigational therapy, ImmunoPulse IL-12, and Merck's approved anti-PD-1 agent, KEYTRUDA (pembrolizumab), in patients with unresectable metastatic melanoma.

18 Aug 2015

Researchers describe central role of mTOR in ageing and age-related diseases

For some, TOR may bring to mind a Celtic mountain or perhaps an Internet privacy group. In the world of molecular biology it's a cellular pathway that's found in everything from yeast to mammals.

18 Aug 2015

RPCI researchers create outreach effort to improve public's participation in biomedical research

Roswell Park Cancer Institute researchers, together with input from African-American community leaders in Buffalo, have created an outreach effort that provides racial/ethnic minority and medically underserved communities with educational programs regarding the public's participation in biomedical research. The program is the basis of a recent study published by a team of local collaborators.

18 Aug 2015

NCI-MATCH phase II precision medicine trial opens through ECOG-ACRIN

The National Cancer Institute-Molecular Analysis for Therapy Choice (NCI-MATCH) phase II precision medicine trial, known to doctors as trial EAY131, is open through the ECOG-ACRIN Cancer Research Group.

18 Aug 2015

CMU BrainHub scientists use non-invasive brain-imaging tool to detect basal ganglia pathways

Certain diseases, like Parkinson's and Huntingdon's disease, are associated with damage to the pathways between the brain's basal ganglia regions. The basal ganglia sits at the base of the brain and is responsible for, among other things, coordinating movement. It is made up of four interconnected, deep brain structures that imaging techniques have previously been unable to visualize.

18 Aug 2015

Scientists identify where the brain records time and place of real-life memories

For the first time, scientists have seen evidence of where the brain records the time and place of real-life memories. Results showed that the similarity of the brain activation patterns when memories were recalled was an indicator of the breadth of space and time between the actual events.

18 Aug 2015

Physicians may now have tools to predict people at greater risk of attempting suicide

People being treated for bipolar disorder and other psychiatric illnesses are at greater risk of attempting suicide, but physicians may now have tools to predict which of those individuals will attempt it and intervene early to prevent such tragedies from occurring.

18 Aug 2015

Obstructive hydrocephalus produces significant decrease in brain neurogenesis

In a group of mice, has been identified that their brain presents degenerative changes similar to aging after two months that their cerebrospinal fluid (CSF) stopped circulating normally within the body and starts to accumulate, as reported by a Mexican group of researchers at the University of Colima.

18 Aug 2015

Nuclear process in the brain may play critical role in health and disease

Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped brain cell, called an astrocyte, may play a critical role in health and disease.

18 Aug 2015

Others consider our moral traits, not memory, to be core component of our identity

We may view our memory as being essential to who we are, but new findings suggest that others consider our moral traits to be the core component of our identity. Data collected from family members of patients suffering from neurodegenerative disease showed that it was changes in moral behavior, not memory loss, that caused loved ones to say that the patient wasn't "the same person" anymore.

18 Aug 2015

FSU study reveals new method for treating diabetes

A new Florida State University study is changing how researchers look at diabetes research and the drugs used to treat the disease.

18 Aug 2015

VA study examines use of medicinal maggots to heal diabetic foot ulcers

Maggot, or larval, therapy has been around since ancient times as a way to heal wounds. Now, the method has gone high-tech--in some ways--and it's being tested in a rigorous clinical trial at the Malcom Randall Veterans Affairs (VA) Medical Center in Gainesville, Fla. Recruitment is now underway.

18 Aug 2015

Music therapy reduces anxiety in women undergoing surgical breast biopsies

A first-of-its-kind study published in the Journal of Clinical Oncology finds that music therapy lessened anxiety for women undergoing surgical breast biopsies for cancer diagnosis and treatment.

18 Aug 2015

Quanta receives i4i award from NIHR to develop new product concept for nocturnal haemodialysis

Quanta Fluid Solutions Ltd, a pioneering developer of advanced haemodialysis systems, announces it has received an Invention for Innovation (i4i) award worth £1.85 million from the National Institute for Health Research - the research arm of the NHS - to develop a new product concept for nocturnal haemodialysis.

18 Aug 2015

Growing availability of heroin changing the face of opiate addiction in the U.S.

The growing availability of heroin, combined with programs aimed at curbing prescription painkiller abuse, may be changing the face of opiate addiction in the U.S., according to sociologists.

18 Aug 2015

Urologists report success in treating bladder issues, pelvic pain through neuromodulation technique

Millions of people suffer from bladder dysfunction, including about 30 million in the U.S. One in seven women experience chronic pelvic pain. These are not only health issues, but quality of life issues.

18 Aug 2015

Scientists map 3-D atomic structure of protein complex that controls neurotransmitter release from brain cells

Scientists have revealed never-before-seen details of how our brain sends rapid-fire messages between its cells. They mapped the 3-D atomic structure of a two-part protein complex that controls the release of signaling chemicals, called neurotransmitters, from brain cells. Understanding how cells release those signals in less than one-thousandth of a second could help launch a new wave of research on drugs for treating brain disorders.

18 Aug 2015

MGH study reveals effects of combined radiation and chemotherapy on the brain tissue of glioblastoma patients

A study from Massachusetts General Hospital Cancer Center researchers - the first to examine the effects of combined radiation and chemotherapy on the healthy brain tissue of glioblastoma patients - reveals not only specific structural changes within patients' brains but also that the effect of cancer therapy on the normal brain appears to be progressive and continues even after radiation therapy has ceased.

18 Aug 2015

Medical Condition News

Omeros reports additional positive data from OMS721 Phase 2 trial for treatment of thrombotic microangiopathies

Researchers test new non-invasive technique that can accurately detect malignant melanoma

First patient enrolled in Phase II trial of ImmunoPulse IL-12 and pembrolizumab combination therapy

Researchers describe central role of mTOR in ageing and age-related diseases

RPCI researchers create outreach effort to improve public's participation in biomedical research

NCI-MATCH phase II precision medicine trial opens through ECOG-ACRIN

CMU BrainHub scientists use non-invasive brain-imaging tool to detect basal ganglia pathways

Scientists identify where the brain records time and place of real-life memories

Physicians may now have tools to predict people at greater risk of attempting suicide

Obstructive hydrocephalus produces significant decrease in brain neurogenesis

Nuclear process in the brain may play critical role in health and disease

Others consider our moral traits, not memory, to be core component of our identity

FSU study reveals new method for treating diabetes

VA study examines use of medicinal maggots to heal diabetic foot ulcers

Music therapy reduces anxiety in women undergoing surgical breast biopsies

Quanta receives i4i award from NIHR to develop new product concept for nocturnal haemodialysis

Growing availability of heroin changing the face of opiate addiction in the U.S.

Urologists report success in treating bladder issues, pelvic pain through neuromodulation technique

Scientists map 3-D atomic structure of protein complex that controls neurotransmitter release from brain cells

MGH study reveals effects of combined radiation and chemotherapy on the brain tissue of glioblastoma patients

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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