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Amgen receives FDA priority review designation for Kyprolis to treat relapsed multiple myeloma

Amgen today announced that the U.S. Food and Drug Administration (FDA) has accepted the supplemental New Drug Application (sNDA) of Kyprolis® (carfilzomib) for Injection for the treatment of patients with relapsed multiple myeloma who have received at least one prior therapy.

30 Mar 2015

New faculty members join UNC Lineberger to help launch immunotherapy clinical trials

Two new faculty members have joined the UNC Lineberger Comprehensive Cancer Center to help launch groundbreaking immunotherapy clinical trials testing an experimental treatment in which patients' own immune cells are genetically engineered to fight their cancer.

30 Mar 2015

CRT, BioInvent, and University of Southampton partner to develop new immunotherapy treatments for cancer

Cancer Research Technology, the commercialization and development arm of Cancer Research UK and BioInvent International today announce the start of a two-year research collaboration with leading antibody researchers at the University of Southampton.

30 Mar 2015

Can-Fite BioPharma's CF101Phase II/III psoriasis trial fails to meet primary endpoint

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today that its Phase II/III psoriasis trial for the Company's drug candidate CF101 did not achieve its primary endpoint.

30 Mar 2015

DURECT initiates DUR-928 multi-dose Phase 1 clinical trial for NAFLD, NASH and AKI

DURECT Corporation today announced that it has initiated a multi-dose Phase 1 clinical trial of an oral formulation of DUR-928, the lead molecule in DURECT's Epigenomic Regulator Program.

30 Mar 2015

Healthcare reform changes boost glucose testing in states with healthcare exchanges

A new study published in a major diabetes journal suggests that healthcare reform changes have boosted glucose testing in states that formed healthcare exchanges. The result confirms Kalorama Information's predictions on the topic.

From Quest Diagnostics 30 Mar 2015

$Two surgical methods safe, effective for healing distal femur fractures$

Two surgical methods safe, effective for healing distal femur fractures

A team of orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania has found that modern technology for healing distal femur fractures is as safe and effective as its more established alternative, without a potential shortfall of the older approach.

30 Mar 2015

Synageva announces submission of Kanuma application to Cofepris for treatment of LAL Deficiency

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare disorders, announced today the submission to the Comisión Federal para la Protección contra Riesgos Sanitarios in Mexico for Kanuma as a treatment for patients with lysosomal acid lipase deficiency (LAL Deficiency), a rare genetic disease with significant morbidity and early mortality.

30 Mar 2015

Clonidine Topical Gel fails to meet primary endpoint in Phase 3 study for treatment of painful diabetic neuropathy

BioDelivery Sciences International, Inc. announced that the primary efficacy endpoint in the Phase 3 clinical study of Clonidine Topical Gel compared to placebo for the treatment of painful diabetic neuropathy did not meet statistical significance, although certain secondary endpoints showed statistically significant improvement over placebo. In addition, a strong safety profile for the product was observed.

30 Mar 2015

Medunik announces availability of PHEBURANE drug in Canada for chronic management of UCD

Medunik Canada, a Canadian pharmaceutical company specialized in rare diseases, is pleased to announce that PHEBURANE (a tasteless oral formulation of sodium phenylbutyrate), is now available for distribution in Canada. PHEBURANE is the first drug to be approved in Canada for the chronic management of urea cycle disorders (UCD) after receiving market authorisation on January 27th, 2015.

30 Mar 2015

Researchers identify bio-markers that could help detect early stage colorectal cancer

Colorectal cancer is the third most common form of cancer globally and the second most common cause of cancer deaths. The chance of a cure is high if the cancer is detected early enough, but early detection is not a given. Researchers from VIB and KU Leuven - together with various European oncology centers, including UZ Leuven - have identified bio-markers that can be incorporated in a new diagnostic test.

30 Mar 2015

Brown fat tissue communicates with the brain through sensory nerves

Brown fat tissue, the body's "good fat," communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat we've lost, according to researchers at Georgia State University.

30 Mar 2015

Study: Mexican Americans spend high proportion of their later years with disability

Life expectancy for Hispanics in the U.S. currently outpaces other ethnic groups, yet a new study finds that Mexican Americans -- especially women who were born in Mexico -- are spending a high proportion of their later years with some form of disability, a fact that suggests a growing need for community assistance and long-term care in the future.

30 Mar 2015

$FLS could reduce healthcare costs associated with osteoporotic fractures$

FLS could reduce healthcare costs associated with osteoporotic fractures

Using a simulation model, Swedish researchers have shown that the implementation of Fracture Liaison Services (FLS) could considerably reduce the human and healthcare costs associated with osteoporotic fractures. The results from the model were presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Milan.

30 Mar 2015

Study compares cost, benefits, complications of uterine-sparing treatments for fibroids

The relative cost, benefits, and complications of three minimally invasive techniques for reducing or eliminating symptomatic uterine fibroids are being compared in women who don't have cancer and want to preserve their uterus.

30 Mar 2015

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

The American Association for Cancer Research will honor Christopher R. Vakoc, MD, PhD, assistant professor at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, with the 35th annual AACR Outstanding Achievement in Cancer Research Award at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

30 Mar 2015

Naldemedine meets primary and secondary endpoints in phase III study for OIC treatment

Naldemedine, an investigational peripherally acting mu-opioid receptor antagonist (PAMORA) under development by Shionogi & Co., Ltd., met its primary and secondary endpoints in a phase III study (COMPOSE I) for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain receiving opioid therapy.

30 Mar 2015

Pain relief from IA injection may not predict better outcomes following arthroscopic hip surgery

How best to treat and recover from complicated hip injuries is a growing field in orthopaedic medicine. While diagnostic hip injections are commonly performed for patients with labral tear to confirm the pain etiology, research presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day suggests that pain relief from this diagnostic injection may not predict better outcomes following arthroscopic hip surgery.

30 Mar 2015

Study demonstrates abnormal vitamin D levels in more than one-third of elite NCAA Division I athletes

A new study presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons found that more than one-third of elite, Division I college athletes may have low levels of vitamin D, which is critical in helping the body to absorb calcium needed to maintain bone mass, and to minimize musculoskeletal pain and injury risk.

30 Mar 2015

Combination treatment improves outcomes in women with ovarian cancer

Medical researchers are always looking for ways to prevent or cure cancer. Given the complexity of this disease, reaching these milestones has been difficult.

30 Mar 2015

Medical Condition News

Amgen receives FDA priority review designation for Kyprolis to treat relapsed multiple myeloma

New faculty members join UNC Lineberger to help launch immunotherapy clinical trials

CRT, BioInvent, and University of Southampton partner to develop new immunotherapy treatments for cancer

Can-Fite BioPharma's CF101Phase II/III psoriasis trial fails to meet primary endpoint

DURECT initiates DUR-928 multi-dose Phase 1 clinical trial for NAFLD, NASH and AKI

Healthcare reform changes boost glucose testing in states with healthcare exchanges

Two surgical methods safe, effective for healing distal femur fractures

Synageva announces submission of Kanuma application to Cofepris for treatment of LAL Deficiency

Clonidine Topical Gel fails to meet primary endpoint in Phase 3 study for treatment of painful diabetic neuropathy

Medunik announces availability of PHEBURANE drug in Canada for chronic management of UCD

Researchers identify bio-markers that could help detect early stage colorectal cancer

Brown fat tissue communicates with the brain through sensory nerves

Study: Mexican Americans spend high proportion of their later years with disability

FLS could reduce healthcare costs associated with osteoporotic fractures

Study compares cost, benefits, complications of uterine-sparing treatments for fibroids

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

Naldemedine meets primary and secondary endpoints in phase III study for OIC treatment

Pain relief from IA injection may not predict better outcomes following arthroscopic hip surgery

Study demonstrates abnormal vitamin D levels in more than one-third of elite NCAA Division I athletes

Combination treatment improves outcomes in women with ovarian cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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