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Researchers assemble comprehensive map of human epigenome

Virtually every cell in the body carries an identical genome. But how is it possible that each of the body's 200 different types of specialized cells - in the heart, brain, bone, skin and elsewhere - develops from the same DNA instruction book?

19 Feb 2015

Epigenome may hold promise for conquering diseases

The human genome project captured the public imagination when its first draft was published 14 years ago this week in the international science journal Nature, but the epigenome may hold the real promise for conquering disease.

19 Feb 2015

Soft drink consumers exposed to unnecessary cancer risk

Public health researchers have analyzed soda consumption data in order to characterize people's exposure to a potentially carcinogenic byproduct of some types of caramel color. Caramel color is a common ingredient in colas and other dark soft drinks. The results show that between 44 and 58 percent of people over the age of six typically have at least one can of soda per day, possibly more, potentially exposing them to 4-methylimidazole (4-MEI), a possible human carcinogen formed during the manufacture of some kinds of caramel color.

19 Feb 2015

NYU Langone, Technion collaborate to advance cancer research

In a groundbreaking step forward to advance global collaboration in the fight against cancer, two of the world's preeminent academic and research institutions -- NYU Langone Medical Center and the Technion-Israel Institute of Technology -- formally announced a $9 million gift from philanthropists Laura and Isaac Perlmutter that will fund two major, joint research endeavors with potentially far-reaching impact in advancing cancer research.

19 Feb 2015

New treatment may bring hope for people suffering from muscle cramps

A new treatment may bring hope for people who suffer from muscle cramps or spasms from neuromuscular disorders, diseases such as multiple sclerosis or simply from nighttime leg cramps that keep people from sleeping, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015.

19 Feb 2015

Gut microbial metabolite of linoleic acid has suppressive effect on intestinal inflammation

Inflammatory bowel diseases (IBDs), including Crohn disease and ulcerative colitis, are hard to completely cure. Globally, IBDs affect more than 4 million people, today. However, Professor Soichi Tanabe (Graduate School of Biosphere Science, Hiroshima University) and his collaborators have demonstrated that 10-hydroxy-cis-12-octadecenoic acid (HYA), a gut microbial metabolite of linoleic acid, has a suppressive effect on intestinal inflammation.

19 Feb 2015

Lupus Research Institute announces this year's Novel Research Grants

As the Lupus Research Institute celebrates its 15th anniversary, the engine of innovation moves forward at accelerated speed with the announcement of this year's Novel Research Grants bringing new talent from a wide diversity of specialties. Each project lives up to the strictest definition of novel – wholly original, never-been-done-before.

19 Feb 2015

Advances in stem cell therapy can improve outcomes for patients with chronic diabetic foot ulcers

According to data presented at the 73rd Annual Scientific Conference of the American College of Foot and Ankle Surgeons, advances in stem cell therapy can significantly improve outcomes for patients with chronic diabetic foot ulcers. Use of stem cells to treat foot problems like diabetic ulcers may speed up the healing process, preventing infection and hospitalization during recovery.

19 Feb 2015

Lupin introduces new InspiraChamber VHC under strategic licensing agreement with InspiRX

Pharma Major Lupin Limited announced today that its US subsidiary, Lupin Pharmaceuticals Inc. (collectively Lupin) has launched the all new InspiraChamber Anti-Static Valved Holding Chamber (VHC) under a strategic licensing agreement with the New Jersey based respiratory research and development company InspiRX Inc.

19 Feb 2015

EC grants orphan drug designation to aTyr Pharma's Resolaris for treatment of FSHD

aTyr Pharma, Inc., a biotherapeutics company engaged in the discovery and development of Physiocrine-based therapeutics to address rare diseases, announced today the European Commission (EC) has granted orphan drug designation to Resolaris for the treatment of facioscapulohumeral muscular dystrophy (FSHD).

19 Feb 2015

Midwest Compassion Center, Dr. Alan Shackelford join forces to treat epilepsy through medical cannabis

Midwest Compassion Center and Dr. Alan Shackelford join forces in the fight to treat epilepsy through the use of medical cannabis at their Will County dispensary. With growing concerns over the potentially negative side effects of pharmaceuticals and their inability to provide adequate symptom control in as many as 30% of patients with seizures, Dr. Shackelford and MCC will collaborate on research with the goal of developing new treatment options for patients dealing with a debilitating illness or condition, including seizures.

19 Feb 2015

First comprehensive maps and analyses of human epigenomes revealed

Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. Epigenomes are patterns of chemical annotations to the genome that determine whether, how, and when genes are activated.

18 Feb 2015

UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

UT Southwestern Medical Center scientists have identified a new biomarker that could help identify patients who are more likely to respond to certain chemotherapies.

18 Feb 2015

Findings may help doctors recommend appropriate treatments, improve patient outcomes

Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once they reach a certain point of degradation, the cell dies. This is one reason that cells are mortal: telomeres only last so long. That is, unless the enzyme telomerase builds new material onto the worn telomeres to reinforce these chromosomal "bumpers". Telomere repair can be a good thing, but in some cases it's not: overactive telomerase can lengthen telomeres until a cell becomes immortal…leading to cancer.

18 Feb 2015

UT Southwestern researchers find that acetate speeds up growth and metastasis of tumors

UT Southwestern Medical Center researchers seeking novel ways to combat cancer found that giving acetate, a major compound produced in the gut by host bacteria, to mice sped up the growth and metastasis of tumors.

18 Feb 2015

Facts about precision medicine

President Barack Obama is requesting an increase of $215 million in the 2016 federal budget to launch the Precision Medicine Initiative. This boost in funding for research will give genetic causes of cancer a national focus specifically around precision or "personalized" treatments for cancer in the future.

18 Feb 2015

President of MD Anderson selected as new fellow of AACR Academy

Ron DePinho, M.D., president of The University of Texas MD Anderson Cancer Center, will be inducted as a new fellow of the American Association for Cancer Research Academy. He joins 10 other cancer leaders in the prestigious academy that recognizes people who have made significant contributions to cancer research.

18 Feb 2015

Oncolytics announces completion of patient enrollment in REOLYSIN Phase II colorectal cancer study

Oncolytics Biotech Inc. today announced that enrollment has been completed in a randomized Phase II study of REOLYSIN in patients with advanced or metastatic colorectal cancer (IND 210). The trial is being sponsored and conducted by the NCIC Clinical Trials Group at Queen's University in Kingston, Ontario.

18 Feb 2015

Dutch doctors share views on euthanasia

Around one in three Dutch doctors would be prepared to help someone with early dementia, mental illness, or who is 'tired of living' to die, reveals a small survey published online in the Journal of Medical Ethics.

18 Feb 2015

Researchers show importance of DNA damage in fine tuning of innate immune system

For the first time scientists from Umeå University show the importance of DNA damage in fine tuning of our innate immune system and hence the ability to mount the optimal inflammatory response to infections and other biological dangers.

18 Feb 2015

Medical Condition News

Researchers assemble comprehensive map of human epigenome

Epigenome may hold promise for conquering diseases

Soft drink consumers exposed to unnecessary cancer risk

NYU Langone, Technion collaborate to advance cancer research

New treatment may bring hope for people suffering from muscle cramps

Gut microbial metabolite of linoleic acid has suppressive effect on intestinal inflammation

Lupus Research Institute announces this year's Novel Research Grants

Advances in stem cell therapy can improve outcomes for patients with chronic diabetic foot ulcers

Lupin introduces new InspiraChamber VHC under strategic licensing agreement with InspiRX

EC grants orphan drug designation to aTyr Pharma's Resolaris for treatment of FSHD

Midwest Compassion Center, Dr. Alan Shackelford join forces to treat epilepsy through medical cannabis

First comprehensive maps and analyses of human epigenomes revealed

UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

Findings may help doctors recommend appropriate treatments, improve patient outcomes

UT Southwestern researchers find that acetate speeds up growth and metastasis of tumors

Facts about precision medicine

President of MD Anderson selected as new fellow of AACR Academy

Oncolytics announces completion of patient enrollment in REOLYSIN Phase II colorectal cancer study

Dutch doctors share views on euthanasia

Researchers show importance of DNA damage in fine tuning of innate immune system

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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