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Research opens door to development of new therapies to block HIV-associated neurocognitive disorders

While antiretroviral therapies have significantly improved and extended the lives of many HIV patients, another insidious and little discussed threat looms for aging sufferers - HIV-associated neurocognitive disorders (HAND). The disorders, which strike more often in HIV patients over age 50, can result in cognitive impairment, mild to severe, making everyday tasks a challenge.

3 Feb 2015

International community funding can significantly reduce cancer deaths in LMICs by 2030

Increased annual international community funding of US$18 billion globally could save three million lives per year by 2030 and many more in succeeding decades,

3 Feb 2015

Sleep apnea may cause some cases of osteoporosis

The daily rhythm of bone turnover is likely important for normal bone health, and recent research suggests that sleep apnea may be an unrecognized cause of some cases of osteoporosis. Sleep apnea's effects on sleep duration and quality, oxygen levels, inflammation, and other aspects of health may have a variety of impacts on bone metabolism.

3 Feb 2015

Researchers are one step closer to devising an approach to identify pancreatic cancer earlier

Pancreatic cancer affects approximately 46,000 people each year in the United States and ranks fourth among the leading causes of cancer-related deaths. Only about 6 percent of individuals with pancreatic cancer will live five years after their diagnosis.

3 Feb 2015

New test can help measure vital aspects of retinal health

New research published in the February 2015 issue of The FASEB Journal details a test developed using mice that can help measure two important aspects of retinal health--the function of retinal blood vessels and light-detecting cells. This approach opens new possibilities for understanding the molecular changes that occur in retinal disease and for evaluating the benefits of treatment early in the course of disease.

3 Feb 2015

ISP shows promise in stopping fatal arrhythmias after heart attack

Case Western Reserve's chemical compound aimed at restoring spinal cord function may have an additional purpose: stopping potentially fatal arrhythmias after heart attack.

3 Feb 2015

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Isis Pharmaceuticals, Inc. announced today top-line results from a Phase 2 study of ISIS-PTP1B Rx in patients with type 2 diabetes. In the Phase 2 study patients treated with ISIS-PTP1B Rx achieved statistically significant reductions in body weight and hemoglobin A1c (HbA1c).

3 Feb 2015

Accelerated Cure Project for MS launches nationwide initiative to fuel multiple sclerosis research

The Accelerated Cure Project for Multiple Sclerosis today launches iConquerMS, the nationwide initiative by and for individuals living with multiple sclerosis who recognize the power of their health data and insights and want to harness that power to fuel research.

3 Feb 2015

Study shows changes in kidney function among sugarcane workers in northwestern Nicaragua

Sugarcane workers in northwestern Nicaragua experienced a decline in kidney function during the harvest, with field workers at greatest risk, suggesting that heat stress or other occupational factors may be playing a role in the high rates of chronic kidney disease in the region, a new study led by Boston University School of Public Health researchers shows.

3 Feb 2015

Understanding how the brain works in individuals with autism

New research could lead to a better understanding of how the brain works in people with autism.

3 Feb 2015

Reversing effects of early stage age-related macular degeneration may be possible

A new technique reported in the February 2015 issue of The FASEB Journal suggests that during early stages, it might be possible to reverse age-related macular degeneration, a leading cause of blindness that is currently irreversible. The treatment involving a nanosecond laser may also have further implications for other eye diseases such as diabetic macular oedema, diabetic retinopathy and retinopathy of prematurity.

3 Feb 2015

CellDetect urine test for detecting bladder cancer meets primary endpoint in multi-center clinical study

BioLight Life Sciences Investments Ltd., a firm that invests in, manages and commercializes biomedical innovations in ophthalmology and cancer diagnostics, announced today that a blinded, multi-center clinical study of the CellDetect non-invasive test for detecting bladder cancer in urine, successfully achieved the study's primary endpoint for effectively detecting the recurrence of bladder cancer in subjects with a history of the disease.

3 Feb 2015

Immuron begins patient recruitment for Phase 2 clinical trial of IMM-124E NASH drug candidate

Australian biopharmaceutical company Immuron Limited has today announced a significant milestone in its Phase 2 clinical trial for non-alcoholic steatohepatitis (NASH) with the recruitment of its first two patients at Duke University in the United States. It is expected that further recruitment at Duke and other sites in the US and Australia will follow in early course.

3 Feb 2015

Findings may lay foundation for treatment of neurodegenerative diseases

This story starts in 1955, upon the death of Albert Einstein, when the pathologist charged with performing the famous scientist's autopsy stole his brain.

3 Feb 2015

International researchers discover gene that causes familial scoliosis

The discovery of the first gene causing familial scoliosis was announced by an international France-Canada research team today. "Mystery surrounds the cause of scoliosis, which is a three dimensional deformation of the vertebral column. Many researchers have been attempting to uncover the origins of this disease, particularly from a genetic point of view," explained leading co-author Dr Florina Moldovan of the University of Montreal and the CHU Sainte Justine research hospital.

3 Feb 2015

Ildong Pharmaceutical to market BELVIQ (lorcaserin HCl) for weight management in South Korea

Arena Pharmaceuticals, Inc. today announced that Ildong Pharmaceutical Co., Ltd., has informed Arena that the Ministry of Food and Drug Safety has approved BELVIQ (lorcaserin HCl) for marketing for weight management in South Korea. Ildong will market and distribute BELVIQ in South Korea under its marketing and supply agreement with Arena's wholly owned subsidiary, Arena Pharmaceuticals GmbH, or Arena GmbH.

3 Feb 2015

Janssen granted Priority Review from FDA for YONDELIS (trabectedin) NDA to treat STS patients

Janssen Research & Development, LLC announced today that the U.S. Food and Drug Administration has granted Priority Review for the New Drug Application (NDA) for YONDELIS (trabectedin) to treat patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes, who have received prior chemotherapy including an anthracycline.

3 Feb 2015

Experts recommend sublingual immunotherapy for treatment of allergic rhinitis

Sublingual immunotherapy is one of several state-of-the-science treatments for allergic rhinitis, or "hay fever," being recommended by a panel of experts in a new guideline published Feb. 2, 2015, by the American Academy of Otolaryngology--Head and Neck Surgery Foundation.

3 Feb 2015

Study identifies correlations between BioLight's TeaRx diagnostic parameters and benchmark tests for dry eye syndrome

BioLight Life Sciences Investments Ltd., a firm that invests in, manages and commercializes biomedical innovations in ophthalmology and cancer diagnostics, today announced the completion of a U.S. clinical study, conducted by Ora, Inc. Andover, MA, designed to compare widely used benchmark tests for dry eye with its TeaRx diagnostic parameters that test components of tear film.

3 Feb 2015

Not all ARB drugs are equally effective at treating heart failure, reveals NSU researcher

Millions of people take angiotensin receptor blockers (ARBs) to help treat heart failure. But it turns out not all ARBs are created equally, according to one Nova Southeastern University researcher's findings.

3 Feb 2015

Medical Condition News

Research opens door to development of new therapies to block HIV-associated neurocognitive disorders

International community funding can significantly reduce cancer deaths in LMICs by 2030

Sleep apnea may cause some cases of osteoporosis

Researchers are one step closer to devising an approach to identify pancreatic cancer earlier

New test can help measure vital aspects of retinal health

ISP shows promise in stopping fatal arrhythmias after heart attack

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Accelerated Cure Project for MS launches nationwide initiative to fuel multiple sclerosis research

Study shows changes in kidney function among sugarcane workers in northwestern Nicaragua

Understanding how the brain works in individuals with autism

Reversing effects of early stage age-related macular degeneration may be possible

CellDetect urine test for detecting bladder cancer meets primary endpoint in multi-center clinical study

Immuron begins patient recruitment for Phase 2 clinical trial of IMM-124E NASH drug candidate

Findings may lay foundation for treatment of neurodegenerative diseases

International researchers discover gene that causes familial scoliosis

Ildong Pharmaceutical to market BELVIQ (lorcaserin HCl) for weight management in South Korea

Janssen granted Priority Review from FDA for YONDELIS (trabectedin) NDA to treat STS patients

Experts recommend sublingual immunotherapy for treatment of allergic rhinitis

Study identifies correlations between BioLight's TeaRx diagnostic parameters and benchmark tests for dry eye syndrome

Not all ARB drugs are equally effective at treating heart failure, reveals NSU researcher

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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