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Phase 2 results from Abbvie’s veliparib study in NSCLC presented at ASCO 2015

AbbVie, a global biopharmaceutical company, today announced findings from a Phase 2 study of the investigational medicine veliparib combined with the chemotherapy regimen carboplatin and paclitaxel that showed an improvement in median progression-free survival (PFS) in patients with previously untreated metastatic or advanced non-small cell lung cancer (NSCLC) who are current smokers.

2 Jun 2015

New data underscores the importance of FoundationOne genomic profiling for treatment of biliary tract cancers

Foundation Medicine, Inc. today presented new data including promising clinical outcomes underscoring the importance of integrating comprehensive genomic profiling with FoundationOne® into clinical oncology care for the treatment of biliary tract cancers.

2 Jun 2015

Helsinn's Akynzeo for CINV prevention receives EC approval

Helsinn, the Swiss Group focused on building quality cancer care, announces today that on 27th May 2015, the European Commission (EC) approved Akynzeo® (netupitant-palonosetron) for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cisplatin-based cancer chemotherapy and moderately emetogenic cancer chemotherapy in the European Union.

2 Jun 2015

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015

NSCLC treatment market forecast to reach $7.9 billion by 2020

The Non-Small Cell Lung Cancer treatment market will be driven primarily by the introduction of numerous premium therapies, particularly in second-line and squamous cell treatment settings, which either replace or combine with generic chemotherapies.

2 Jun 2015

Fennec presents positive interim results from phase III trial of sodium thiosulphate at ASCO 2015

Fennec Pharmaceuticals, Inc., announced the presentation of positive interim results from a poster presented today entitled, "Anti-tumor efficacy in SIOPEL6: A multi-centre open label randomised phase III trial of the efficacy of sodium thiosulphate (STS) in reducing ototoxicity in patients receiving cisplatin (Cis) monotherapy for standard risk hepatoblastoma (SR-HB)."

2 Jun 2015

Substantial pharmacogenetic information available on cardiovascular drugs

There is a wealth of published information describing interactions between drugs used to treat cardiovascular disease and the genetic variations that can affect how patients respond to them. But few heart specialists make routine use of this potentially life-saving data.

2 Jun 2015

Talimogene laherparepvec treatment shows durable clinical responses in advanced-stage melanoma patients

Research led by Howard L. Kaufman, MD, FACS, associate director for clinical science and chief surgical officer at Rutgers Cancer Institute of New Jersey and colleagues, shows advanced-stage melanoma patients have significant improvement in durable response rate and a trend toward improved survival when treated with a genetically-modified form of a herpes virus, whose native form causes the common cold sore.

2 Jun 2015

Study addresses children's basic perspectives on living with Type 1 diabetes

If a picture is worth a thousand words, UF Health Type 1 diabetes researchers and their colleagues have tapped into an encyclopedia, revealing new insights into how young people cope with the disease.

2 Jun 2015

New York Eye and Ear Infirmary of Mount Sinai observes June 1st as World Orthoptics Day

New York Eye and Ear Infirmary of Mount Sinai joins with the International Orthoptic Association to observe June 1st as World Orthoptics Day.

2 Jun 2015

Decipher genomic analysis platform predicts tumor responsiveness to neoadjuvant chemotherapy in MIBC patients

GenomeDx Biosciences today announced that the robust Decipher genomic analysis platform, successfully classified various subtypes of bladder cancer based on the genomic expression of certain biomarkers, including one type associated with resistance to cisplatin-based chemotherapy. Importantly, this unique genomic signature has potential as a tool to predict tumor responsiveness to neoadjuvant chemotherapy in patients with muscle-invasive bladder cancers (MIBC).

2 Jun 2015

Using earlier surgical intervention more beneficial to patient with degenerative mitral valve disease

A more aggressive approach to treating degenerative mitral valve disease, using earlier surgical intervention and less invasive techniques, is more beneficial to the patient than "watchful waiting," according to an article in the June 2015 issue of The Annals of Thoracic Surgery.

2 Jun 2015

Combination of Tafinlar and Mekinist drugs improves outcomes in patients with metastatic melanoma

Novartis today announced data from the Phase III COMBI-d study showing a significant survival benefit for patients with BRAF V600E/K mutation-positive metastatic melanoma when treated with the combination of Tafinlar (dabrafenib) and Mekinist (trametinib) compared to Tafinlar monotherapy alone.

2 Jun 2015

Surgical resection, chemo and radiation therapy combination could benefit metastatic NSCLC patients

Patients diagnosed with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection (removal of all or part of the lung) in combination with chemotherapy and radiation therapy, according to an article in the June 2015 issue of The Annals of Thoracic Surgery.

2 Jun 2015

Researchers identify previously unknown gene mutation that causes achromatopsia

People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.

2 Jun 2015

Yeast could serve as a test organism for study of human obesity

A team of biologists and a mathematician have identified and characterized a network composed of 94 proteins that work together to regulate fat storage in yeast.

2 Jun 2015

Zinc levels linked to formation of kidney stone

New research on kidney stone formation reveals that zinc levels may contribute to kidney stone formation, a common urinary condition that can cause excruciating pain. The research found that zinc may be the core by which stone formation starts.

2 Jun 2015

New UA research reveals factors that can impact aging adults' quality of life

As the world's population of older adults increases, so do conversations around successful aging -- including seniors' physical, mental and social well-being.

2 Jun 2015

Centinel Spine achieves milestone implantation of 20,000 STALIF C cervical integrated interbody devices

Centinel Spine, Inc., the pioneer of spinal Stand-Alone, No-Profile®, Integrated Interbody™ devices has now implanted 20,000 STALIF C cervical Integrated Interbody devices. The STALF C device is implanted during cervical fusion procedures to treat degenerative spinal disorders.

2 Jun 2015

More patients experience phantom eye symptoms every day, say University of Liverpool researchers

Researchers from the University of Liverpool have found that approximately half of patients who have an eye removed because of a form of eye cancer experience 'phantom eye syndrome.'

2 Jun 2015

Medical Condition News

Phase 2 results from Abbvie’s veliparib study in NSCLC presented at ASCO 2015

New data underscores the importance of FoundationOne genomic profiling for treatment of biliary tract cancers

Helsinn's Akynzeo for CINV prevention receives EC approval

Genetically-programmed probiotics could help detect liver cancer metastases early-on

NSCLC treatment market forecast to reach $7.9 billion by 2020

Fennec presents positive interim results from phase III trial of sodium thiosulphate at ASCO 2015

Substantial pharmacogenetic information available on cardiovascular drugs

Talimogene laherparepvec treatment shows durable clinical responses in advanced-stage melanoma patients

Study addresses children's basic perspectives on living with Type 1 diabetes

New York Eye and Ear Infirmary of Mount Sinai observes June 1st as World Orthoptics Day

Decipher genomic analysis platform predicts tumor responsiveness to neoadjuvant chemotherapy in MIBC patients

Using earlier surgical intervention more beneficial to patient with degenerative mitral valve disease

Combination of Tafinlar and Mekinist drugs improves outcomes in patients with metastatic melanoma

Surgical resection, chemo and radiation therapy combination could benefit metastatic NSCLC patients

Researchers identify previously unknown gene mutation that causes achromatopsia

Yeast could serve as a test organism for study of human obesity

Zinc levels linked to formation of kidney stone

New UA research reveals factors that can impact aging adults' quality of life

Centinel Spine achieves milestone implantation of 20,000 STALIF C cervical integrated interbody devices

More patients experience phantom eye symptoms every day, say University of Liverpool researchers

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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