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Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Eli Lilly and Company and AstraZeneca today announced enrollment of the first patient into AMARANTH, a Phase II/III study of an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease.

1 Dec 2014

Different forms of ASIC1a gene associated with panic disorder

Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort.

1 Dec 2014

Griffith University student explores impact of computer games on older adults

Griffith University PhD student, Milton Nyawata, is looking for people over the age of 60 to take part in a study into the effects of computer games on older Australians.

1 Dec 2014

Researchers identify new genetic biomarkers that predict outcomes for patients with bowel cancer

Researchers at University of Limerick and University Hospital Limerick have identified several new genetic biomarkers which better predict outcomes for patients with bowel/colorectal cancer. The research team identified genes that are predictors of cancer recurrence and can also help to identify a patients’ suitability to specific types of chemotherapy.

1 Dec 2014

Bilingualism has protective effect in delaying Alzheimer's disease symptoms

A new study at Ghent University has established that the symptoms of Alzheimer disease (AD) manifest themselves about four to five years later in bilinguals as opposed to monolinguals. In bilinguals, the disease onset was estimated at the age of 77, while in monolinguals, this was at the age of 73.

1 Dec 2014

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

Pharmacyclics, Inc.today announced the acceptance of a Type II variation application for IMBRUVICA (ibrutinib) by the European Medicines Agency.

1 Dec 2014

CTI BioPharma announces upcoming presentations of pacritinib data at ASH Annual Meeting

CTI BioPharma Corp. (CTI) today announced the upcoming presentations of data highlighting pacritinib, an oral multikinase inhibitor with dual activity against JAK2 and FLT3, and tosedostat, an oral selective inhibitor of aminopeptidases, at the 56th American Society of Hematology (ASH) Annual Meeting and Exposition, being held December 6-9 in San Francisco, CA.

1 Dec 2014

DTI may play role in assessing brain damage in early Alzheimer's disease

Changes in brain connections visible on MRI could represent an imaging biomarker of Alzheimer's disease, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2014

PET/CT may improve differentiation of PTSD from MTBI

Hybrid imaging with positron emission tomography and computed tomography (PET/CT) in the pituitary region of the brain is a promising tool for differentiating military veterans with post-traumatic stress disorder (PTSD) from those with mild traumatic brain injury (MTBI), according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2014

Brain changes seen in high school football players after one season

Some high school football players exhibit measurable brain changes after a single season of play even in the absence of concussion, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2014

New active substance effectively combats Philadelphia chromosome-positive leukaemia

Haematologists from Goethe University Frankfurt, working with a Russian pharmaceutical company, have developed a new active substance that effectively combats the most aggressive forms of Philadelphia chromosome-positive leukaemia.

29 Nov 2014

Drinking 3-5 cups of coffee per day may protect against Alzheimer’s Disease

Drinking 3-5 cups of coffee per day may help to protect against Alzheimer’s Disease, according to research highlighted in an Alzheimer Europe session report published by the Institute for Scientific Information on Coffee, a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health.

29 Nov 2014

EMAHSN extends IPS scheme to support people with mental health illness

The 8 December will see the first step in an East Midlands wide approach to supporting people with mental health illness back in to work or education. The East Midlands Academic Health Science Network is championing and extending a widely proven scheme called Individual Placement and Support (IPS) across the region.

28 Nov 2014

Better Care for People with Bipolar Disorder: A new booklet to be launched in December 2014

Bipolar Disorder is in the top 20 causes of years lost due to illness in the world among all health conditions. It affects 1.4% of the population and lasts for the rest of the person’s life. People diagnosed with Bipolar Disorder are 20 times more likely than the general public to commit suicide. In 2007 service provision costs for Bipolar Disorder and related conditions were estimated to be £1.6 billion. This is projected to increase to £2.6 billion by 2026.

28 Nov 2014

Researchers use mathematical models to predict how immune cells respond to disease

Walter and Eliza Hall Institute researchers have defined for the first time how the size of the immune response is controlled, using mathematical models to predict how powerfully immune cells respond to infection and disease.

28 Nov 2014

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine.

28 Nov 2014

UCL research opens up new way to treat neurological disorders

The way that tetanus neurotoxin enters nerve cells has been discovered by UCL scientists, who showed that this process can be blocked, offering a potential therapeutic intervention for tetanus. This newly-discovered pathway could be exploited to deliver therapies to the nervous system, opening up a whole new way to treat neurological disorders such as motor neuron disease and peripheral neuropathies.

28 Nov 2014

Behavioural, drug interventions aiming to prevent progression to diabetes equally effective for both sexes

Behavioural and drug interventions aiming to prevent people with prediabetes progressing to full blown type 2 diabetes are equally effective for both sexes at preventing progression and reducing weight, according to a new systematic review and meta-analysis.

28 Nov 2014

New research examines effect on Tourette's sufferers when exposed to their own image

Tourette's syndrome is characterised by tics caused in many by premonitory urges; sensations which give patients compulsion to act to relieve discomfort. Habit reversal therapy conditions patients into heightened awareness of premonitory urges and forced counteraction of the tic.

28 Nov 2014

Study finds striking gap in cancer survival between countries and regions

The CONCORD-2 study, published in The Lancet, reports 5-year survival estimates for 25·7 million cancer patients diagnosed with one of 10 common cancers and 75 000 children diagnosed with acute lymphoblastic leukaemia between 1995 and 2009, using individual patient data from 279 cancer registries in 67 countries.

28 Nov 2014

Medical Condition News

Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Different forms of ASIC1a gene associated with panic disorder

Griffith University student explores impact of computer games on older adults

Researchers identify new genetic biomarkers that predict outcomes for patients with bowel cancer

Bilingualism has protective effect in delaying Alzheimer's disease symptoms

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

CTI BioPharma announces upcoming presentations of pacritinib data at ASH Annual Meeting

DTI may play role in assessing brain damage in early Alzheimer's disease

PET/CT may improve differentiation of PTSD from MTBI

Brain changes seen in high school football players after one season

New active substance effectively combats Philadelphia chromosome-positive leukaemia

Drinking 3-5 cups of coffee per day may protect against Alzheimer’s Disease

EMAHSN extends IPS scheme to support people with mental health illness

Better Care for People with Bipolar Disorder: A new booklet to be launched in December 2014

Researchers use mathematical models to predict how immune cells respond to disease

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

UCL research opens up new way to treat neurological disorders

Behavioural, drug interventions aiming to prevent progression to diabetes equally effective for both sexes

New research examines effect on Tourette's sufferers when exposed to their own image

Study finds striking gap in cancer survival between countries and regions

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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