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Researchers reveal how cancer cells succeed at entrapping genetic program of growth inhibition

Healthy cells reduce their growth when there is a lack of oxygen (hypoxia). This makes it even more surprising that hypoxia is a characteristic feature of malignant tumours. In two publications in the current edition of the "Nature Communications" journal, researchers from Goethe University and Justus-Liebig-University of Giessen report on how cancer cells succeed at circumventing the genetic program of growth inhibition.

25 Nov 2014

Oxford BioTherapeutics, Menarini Group initiate phase I study of OBT357 (MEN1112) for AML treatment

Oxford BioTherapeutics and Berlin Chemie/ Menarini Biotech/ Menarini Ricerche (belonging to Menarini Group) announce today that they have initiated the first-in-human clinical study of OBT357 (MEN1112), a novel enhanced antibody for the treatment of acute myeloid leukemia (AML).

25 Nov 2014

VeraVia releases information to help men achieve better weight loss strategy

A recent study published in the British Journal of General Practice found that physicians have difficulty visually diagnosing obesity in men. San Diego fitness retreat VeraVia has released information for men to help them understand how their own weight loss differs from women. VeraVia founder and CEO Wyatt Chapman says, "Achieving the best weight loss strategy for your body and lifestyle can be complicated.

25 Nov 2014

Apitope's ATX-F8-117 granted orphan medicinal product designation for treatment of haemophilia A

Apitope, the drug discovery and development company focused on disease-modifying treatments for patients with autoimmune and allergic diseases, announced today that the European Medicines Agency Committee for Orphan Medicinal Products has granted orphan medicinal product designation to ATX-F8-117 for the treatment of haemophilia A.

25 Nov 2014

TSRI scientists find simple method to convert human skin cells into sensory neurons

A team led by scientists from The Scripps Research Institute has found a simple method to convert human skin cells into the specialized neurons that detect pain, itch, touch and other bodily sensations. These neurons are also affected by spinal cord injury and involved in Friedreich's ataxia, a devastating and currently incurable neurodegenerative disease that largely strikes children.

25 Nov 2014

Ohio State researchers study repetitive transcranial magnetic stimulation for stroke rehabilitation

Researchers at The Ohio State University Wexner Medical Center are trying to help patients who have suffered a stroke to improve arm movement by stimulating the brain using a device called a Transcranial Magnetic Stimulator (TMS). By using TMS to reduce brain activity on the side that was not injured by the stroke, the injured side may have a better chance of recovering.

25 Nov 2014

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has presented Andrew Hattersley, DM, and Mark McCarthy, MD, with the 16th Naomi Berrie Award for Outstanding Research in Diabetes, for their work on the genetics of the disease. Their research has contributed to the discovery of new forms of the disease, improvements in diagnostic methodology, and the development of more effective treatments.

25 Nov 2014

Research findings could provide insight into how doctors could restore human memory

UCLA neurophysicists have found that space-mapping neurons in the brain react differently to virtual reality than they do to real-world environments. Their findings could be significant for people who use virtual reality for gaming, military, commercial, scientific or other purposes.

25 Nov 2014

Plaque buildup in the arteries associated with mild cognitive impairment

In a study of nearly 2,000 adults, researchers found that a buildup of plaque in the body's major arteries was associated with mild cognitive impairment. Results of the study conducted at the University of Texas Southwestern Medical Center will be presented next week at the annual meeting of the Radiological Society of North America.

25 Nov 2014

Adults diagnosed with retinoblastoma as infants perform better on tasks, study finds

Most long-term survivors of retinoblastoma, particularly those who had been diagnosed with tumors by their first birthdays, have normal cognitive function as adults, according to a St. Jude Children's Research Hospital study. The research, which appears in the current issue of the journal Cancer, found that the vast majority of survivors work full time, live independently and fulfill other milestones of adult life.

25 Nov 2014

Protein that awakens brain from sleep may fight against Alzheimer's disease

A protein that stimulates the brain to awaken from sleep may be a target for preventing Alzheimer's disease, a study by researchers at Washington University School of Medicine in St. Louis suggests.

25 Nov 2014

Dantrolene drug may be effective treatment for rare form of diabetes

A commonly prescribed muscle relaxant may be an effective treatment for a rare but devastating form of diabetes, researchers at Washington University School of Medicine in St. Louis report.

24 Nov 2014

UC San Diego Health System opens nation's first angioedema treatment center

UC San Diego Health System in partnership with the U.S. Hereditary Angioedema Association, a non-profit patient advocacy organization, has opened the nation's first dedicated center for diagnosing and treating diverse forms of swelling, known collectively as angioedema.

24 Nov 2014

ADHD information on social media: an interview with Gemma Ryan

It came about through the implementation of another ADHD project called One Stop Shop, which is a collaborative project with Leicestershire Partnership NHS trust (LPT) and ADHD Solutions, a charitable support organization.

From University of Derby Online Learning 24 Nov 2014

New, enhanced MRI identifies brain injury in BBB of football players following mild concussions

A new, enhanced MRI diagnostic approach was, for the first time, able to identify significant damage to the blood-brain barrier (BBB) of professional football players following "unreported" trauma or mild concussions. Published in the current issue of JAMA Neurology, this study could improve decision making on when an athlete should "return to play."

24 Nov 2014

People with sleep apnea have lower peak oxygen uptake during aerobic activity

People with moderate to severe obstructive sleep apnea may have an intrinsic inability to burn high amounts of oxygen during strenuous aerobic exercise, according to a new study led by researchers at University of California, San Diego School of Medicine.

24 Nov 2014

Scientists discover that brown fat could be used to manage type 2 diabetes

Scientists from Monash University and Stockholm University have discovered that brown fat, nicknamed the 'good fat' because it warms up the body in cold temperatures, burning up calories in the process, also 'hoovers up' excess sugar.

24 Nov 2014

New cell therapy offers hope for patients with liver cirrhosis

Liver disease patients could be helped by a new cell therapy to treat the condition.

24 Nov 2014

Raising awareness of sickle cell disease risks

Members of the public in sub-Saharan Africa who are carriers of the hereditary disease sickle cell disease must be educated aggressively through public health campaigns to raise awareness of the risks of parenting offspring with the disease if their partner is also a carrier, according to research published in the International Journal of Medical Engineering and Informatics.

24 Nov 2014

Authors review current progress in developing transgenic pig models for human diseases

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research.

24 Nov 2014

Medical Condition News

Researchers reveal how cancer cells succeed at entrapping genetic program of growth inhibition

Oxford BioTherapeutics, Menarini Group initiate phase I study of OBT357 (MEN1112) for AML treatment

VeraVia releases information to help men achieve better weight loss strategy

Apitope's ATX-F8-117 granted orphan medicinal product designation for treatment of haemophilia A

TSRI scientists find simple method to convert human skin cells into sensory neurons

Ohio State researchers study repetitive transcranial magnetic stimulation for stroke rehabilitation

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Research findings could provide insight into how doctors could restore human memory

Plaque buildup in the arteries associated with mild cognitive impairment

Adults diagnosed with retinoblastoma as infants perform better on tasks, study finds

Protein that awakens brain from sleep may fight against Alzheimer's disease

Dantrolene drug may be effective treatment for rare form of diabetes

UC San Diego Health System opens nation's first angioedema treatment center

ADHD information on social media: an interview with Gemma Ryan

New, enhanced MRI identifies brain injury in BBB of football players following mild concussions

People with sleep apnea have lower peak oxygen uptake during aerobic activity

Scientists discover that brown fat could be used to manage type 2 diabetes

New cell therapy offers hope for patients with liver cirrhosis

Raising awareness of sickle cell disease risks

Authors review current progress in developing transgenic pig models for human diseases

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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