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Inventiva’s IVA337 receives EMA COMP positive opinion on orphan drug designation for SSc treatment

Inventiva, a drug discovery company that focuses on therapeutic approaches involving transcription factors and epigenetic targets, today announces that the Committee for Orphan Medicinal Products (COMP) at the European Medicines Agency (EMA) has given a positive opinion on the designation of IVA337 as an orphan medicinal product.

4 Nov 2014

AbbVie and Myriad Genetics expand Tumor BRACAnalysis CDx collaboration

Myriad Genetics, Inc. announced today that it has signed an expanded companion diagnostic agreement with AbbVie, Inc., a leading global biopharmaceutical company to use Tumor BRACAnalysis CDx™ as a companion diagnostic in support of AbbVie’s novel poly (ADP-ribose) polymerase or PARP inhibitor, veliparib.

4 Nov 2014

Astellas, Dana-Farber to develop K-Ras inhibitors for treatment of lung, pancreatic cancers

Dana-Farber Cancer Institute (Dana-Farber) and Astellas Pharma Inc. today announced a three-year collaboration to research and develop small molecule inhibitors of oncogenic K-Ras for the treatment of cancer, including lung cancer.

4 Nov 2014

Seno Imagio breast imaging system and associated predictive model can help eliminate breast biopsies

Seno Medical Instruments, Inc., the company pioneering the development of opto-acoustic technology as a new tool to improve the process of diagnosing breast cancer, announced that the use of the Seno Imagio breast imaging system and the associated predictive model appear to have the potential to significantly improve the physicians’ ability to accurately rule out breast cancer compared to traditional ultrasound alone.

4 Nov 2014

Researchers identify potential therapeutic target for glioblastoma

A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme a promising therapeutic target.

4 Nov 2014

New dialysis decision aid can benefit patients with kidney failure

A KIDNEY dialysis decision aid, enabling patients with decreasing kidney function to better assess which treatment is right for them, has been developed by Kidney Research UK as part of a study in which Sheffield Teaching Hospitals NHS Foundation Trust was involved.

4 Nov 2014

Transition Therapeutics presents Phase 2 study of ELND005 drug for bipolar disorder

Transition Therapeutics Inc. ("Transition" or the "Company") today announced findings from a Phase 2 study of neuropsychiatric drug candidate, ELND005, as an adjunctive maintenance treatment for bipolar disorder type I patients (BPD).

4 Nov 2014

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.

3 Nov 2014

Findings could lead to single blood test for early detection of many types of cancer

Scientists have identified more than 800 markers in the blood of cancer patients that could help lead to a single blood test for early detection of many types of cancer in future, according to research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool today (Sunday).

3 Nov 2014

New policy targeting hospital readmissions for COPD may hurt vulnerable patients, say experts

Last week, the federal government revealed that it will fine more than 2,600 hospitals in the coming year, because too many Medicare patients treated at these hospitals are ending up back in the hospital within 30 days of going home. Two new conditions have been added in this round of penalties: elective hip and knee replacement and chronic lung disease.

3 Nov 2014

Davita Kidney Care joins fight against diabetes during National Diabetes Month

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. (NYSE: DVA) and a leading provider of kidney care services, joins the fight against diabetes during National Diabetes Month this November by sharing suggestions and resources to help individuals manage the disease.

3 Nov 2014

Novo Nordisk introduces NovoRapid PumpCart insulin pump

Today, Novo Nordisk launches NovoRapid PumpCart, the first prefilled pump cartridge with an insulin analogue that has been specifically designed for insulin pumps. This new treatment solution, which contains NovoRapid (insulin aspart) – a rapid-acting insulin from Novo Nordisk – is expected to make insulin pump therapy more convenient for people with diabetes and their care staff.

From Novo Nordisk 3 Nov 2014

Researchers to develop new tests to evaluate cognitive growth in people with intellectual disability

Leading researchers, funded through a new, five-year, $3.2 million grant from the National Institutes of Health, are collaborating to develop and evaluate tests designed to measure and track changes in the cognitive functioning of people who typically are difficult to assess accurately: those with an intellectual disability, formerly termed mental retardation.

3 Nov 2014

Tau proteins spur neuron death in Alzheimer's disease

New research points to tau, not amyloid-beta (Abeta) plaque, as the seminal event that spurs neuron death in disorders such as Alzheimer's disease. The finding, which dramatically alters the prevailing theory of Alzheimer's development, also explains why some people with plaque build-up in their brains don't have dementia.

3 Nov 2014

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, researchers say.

3 Nov 2014

Melbourne researchers reveal key steps involved in programmed cell death

Melbourne researchers have uncovered key steps involved in programmed cell death, offering new targets for the treatment of diseases including lupus, cancers and neurodegenerative diseases.

31 Oct 2014

Researchers find independent predictors of end stage renal disease in teens

Researchers at örebro University found that high blood pressure, being overweight, elevation of a blood marker indicating inflammation, or the presence of protein in the urine in otherwise healthy teenage males were all independent predictors of end stage renal disease (ESRD) in later in life.

31 Oct 2014

Broad Institute, UC Berkeley and UCSC receive NCI Cancer Genomics Cloud Pilot contract

A team from the Broad Institute, the University of California, Berkeley, and the University of California, Santa Cruz, was awarded one of three National Cancer Institute Cancer Genomics Cloud Pilot contracts with the goal of building a system that will enable large-scale analysis of The Cancer Genome Atlas and other datasets by co-locating the data and the required computing resources in one cloud environment.

31 Oct 2014

Rice-led research shows how migratory cancer cells acquire 'stem-like' properties

In the first study of its kind, Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The research reveals a common pattern in the decision-making that allows cancer cells to both migrate and form new tumors. Researchers say the commonality may open the door to new drugs that interfere with the genetic switches that cancer must flip to form both cancer stem cells and circulating tumor cells -- two of the main players in cancer metastasis.

31 Oct 2014

Insomnia contributes to deaths caused by motor vehicle crashes, other fatal injuries

New research suggests that insomnia is a major contributor to deaths caused by motor vehicle crashes and other unintentional fatal injuries. The results underscore the importance of the "Sleep Well, Be Well" campaign of the National Healthy Sleep Awareness Project.

31 Oct 2014

Medical Condition News

Inventiva’s IVA337 receives EMA COMP positive opinion on orphan drug designation for SSc treatment

AbbVie and Myriad Genetics expand Tumor BRACAnalysis CDx collaboration

Astellas, Dana-Farber to develop K-Ras inhibitors for treatment of lung, pancreatic cancers

Seno Imagio breast imaging system and associated predictive model can help eliminate breast biopsies

Researchers identify potential therapeutic target for glioblastoma

New dialysis decision aid can benefit patients with kidney failure

Transition Therapeutics presents Phase 2 study of ELND005 drug for bipolar disorder

UC Davis researchers link increased body fat and lethal drug reactions in mice

Findings could lead to single blood test for early detection of many types of cancer

New policy targeting hospital readmissions for COPD may hurt vulnerable patients, say experts

Davita Kidney Care joins fight against diabetes during National Diabetes Month

Novo Nordisk introduces NovoRapid PumpCart insulin pump

Researchers to develop new tests to evaluate cognitive growth in people with intellectual disability

Tau proteins spur neuron death in Alzheimer's disease

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

Melbourne researchers reveal key steps involved in programmed cell death

Researchers find independent predictors of end stage renal disease in teens

Broad Institute, UC Berkeley and UCSC receive NCI Cancer Genomics Cloud Pilot contract

Rice-led research shows how migratory cancer cells acquire 'stem-like' properties

Insomnia contributes to deaths caused by motor vehicle crashes, other fatal injuries

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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