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Researchers use mathematical models to predict how immune cells respond to disease

Walter and Eliza Hall Institute researchers have defined for the first time how the size of the immune response is controlled, using mathematical models to predict how powerfully immune cells respond to infection and disease.

28 Nov 2014

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine.

28 Nov 2014

UCL research opens up new way to treat neurological disorders

The way that tetanus neurotoxin enters nerve cells has been discovered by UCL scientists, who showed that this process can be blocked, offering a potential therapeutic intervention for tetanus. This newly-discovered pathway could be exploited to deliver therapies to the nervous system, opening up a whole new way to treat neurological disorders such as motor neuron disease and peripheral neuropathies.

28 Nov 2014

Behavioural, drug interventions aiming to prevent progression to diabetes equally effective for both sexes

Behavioural and drug interventions aiming to prevent people with prediabetes progressing to full blown type 2 diabetes are equally effective for both sexes at preventing progression and reducing weight, according to a new systematic review and meta-analysis.

28 Nov 2014

New research examines effect on Tourette's sufferers when exposed to their own image

Tourette's syndrome is characterised by tics caused in many by premonitory urges; sensations which give patients compulsion to act to relieve discomfort. Habit reversal therapy conditions patients into heightened awareness of premonitory urges and forced counteraction of the tic.

28 Nov 2014

Study finds striking gap in cancer survival between countries and regions

The CONCORD-2 study, published in The Lancet, reports 5-year survival estimates for 25·7 million cancer patients diagnosed with one of 10 common cancers and 75 000 children diagnosed with acute lymphoblastic leukaemia between 1995 and 2009, using individual patient data from 279 cancer registries in 67 countries.

28 Nov 2014

Study: Five-year survival rate for advanced-stage laryngeal cancer higher than national levels

The five-year survival rate for advanced-stage laryngeal cancer was higher than national levels in a small study at a single academic center performing a high rate of surgical therapy, including a total laryngectomy (removal of the voice box), to treat the disease, despite a national trend toward organ preservation, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery.

28 Nov 2014

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

People affected by a common inherited form of autism could be helped by a drug that is being tested as a treatment for cancer.

27 Nov 2014

Researchers identify mechanism linked to brain damage

Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims--and are now searching for drugs to block it.

27 Nov 2014

Hovione submits first IND Application with FDA for minocycline gel

Hovione announced today it has filed its first Investigational New Drug (IND) Application with the U.S. Food and Drug Administration. This event represents a milestone in Hovione's strategy of developing improved drug delivery options for established drugs.

27 Nov 2014

Immune-suppressing protein may predict how patients respond to treatment

The presence of an immune-suppressing protein in non-cancerous immune cells may predict how patients with different types of cancer respond to treatment, a multi-center phase I study using an investigational immune therapy drug has found.

27 Nov 2014

Dresden scientists get access to the World's second-fastest computer for cancer research

For their calculations, researchers at the Helmholtz-Zentrum Dresden-Rossendorf will now, starting in 2015, have access to the World's second-fastest computer. The Dresden research initiative is one of 56 projects the US Department of Energy has granted access to Titan as part of their INCITE program.

27 Nov 2014

55% of people with dementia have never seen a doctor, shows study

The majority of people with dementia have never seen a doctor about their memory and thinking problems, according to a new study published in the November 26, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

27 Nov 2014

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

Professor Simon Rule, Professor in Haematology at Plymouth University Peninsula Schools of Medicine and Dentistry and Consultant Haematologist at Plymouth Hospitals NHS Trust, has been awarded a significant grant by Cancer Research UK to carry out a research study into the treatment of older patients with mantle cell lymphoma.

27 Nov 2014

Cedars-Sinai Medical Center releases November tip sheet of story ideas

Following is the November 2014 tip sheet of story ideas from Cedars-Sinai Medical Center.

27 Nov 2014

Leading medical experts across the UK call for radical scale up of liver disease treatment

Leading medical experts today [Thursday 27 November] warn that rising numbers of deaths from liver disease - already the UK's third commonest cause of premature death - will be unavoidable without radical improvements in treatment and detection services, and tougher government policies to control the excessive alcohol use and obesity responsible for much of the national burden of liver disease.

27 Nov 2014

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret.

27 Nov 2014

GABA injections prevent and reverse Type 1 diabetes in mice

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

27 Nov 2014

Many older adults with memory problems and dementia go unscreened, untreated

Despite clear signs that their memory and thinking abilities have gone downhill, more than half of seniors with these symptoms haven't seen a doctor about them, a new study finds.

27 Nov 2014

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Cancer stem cells are particularly difficult to eradicate and are at the heart of why it is so hard to more effectively treat cancer patients, as the post-treatment survival of cancer stem cells drives tumour recurrence, the systemic spread of cancer and, ultimately, treatment failure.

From The University of Manchester 27 Nov 2014

Medical Condition News

Researchers use mathematical models to predict how immune cells respond to disease

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

UCL research opens up new way to treat neurological disorders

Behavioural, drug interventions aiming to prevent progression to diabetes equally effective for both sexes

New research examines effect on Tourette's sufferers when exposed to their own image

Study finds striking gap in cancer survival between countries and regions

Study: Five-year survival rate for advanced-stage laryngeal cancer higher than national levels

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

Researchers identify mechanism linked to brain damage

Hovione submits first IND Application with FDA for minocycline gel

Immune-suppressing protein may predict how patients respond to treatment

Dresden scientists get access to the World's second-fastest computer for cancer research

55% of people with dementia have never seen a doctor, shows study

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

Cedars-Sinai Medical Center releases November tip sheet of story ideas

Leading medical experts across the UK call for radical scale up of liver disease treatment

External artificial pancreas improves glucose control, reduces hypoglycemia risk

GABA injections prevent and reverse Type 1 diabetes in mice

Many older adults with memory problems and dementia go unscreened, untreated

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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