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Amgen seeks EMA approval for marketing talimogene laherparepvec

Amgen today announced the submission of a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) via the centralized procedure for talimogene laherparepvec seeking approval for the treatment of adults with melanoma that is regionally or distantly metastatic.

2 Sep 2014

MEI Pharma completes patient enrollment in Pracinostat Phase II trial for treatment of MDS

MEI Pharma, Inc., an oncology company focused on the clinical development of novel therapies for cancer, announced today that it has completed enrollment in a randomized Phase II clinical trial of its lead investigational drug candidate Pracinostat in combination with azacitidine in patients with previously untreated intermediate-2 or high-risk myelodysplastic syndrome (MDS).

2 Sep 2014

Coffee increases risk of prediabetes in young adults with hypertension

Coffee increases the risk of prediabetes in young adults with hypertension who are slow caffeine metabolisers, according to results from the HARVEST study presented at ESC Congress today by Dr Lucio Mos from Italy. People who drank more than three cups of coffee per day doubled their risk of prediabetes.

2 Sep 2014

Concordia's subsidiary signs collaboration deal with Orphan Canada for PHOTOFRIN

Concordia Healthcare Corp., a diverse healthcare company focused on legacy pharmaceutical products, orphan drugs, and medical devices for the diabetic population, today announced that its subsidiary, Pinnacle Biologics, Inc., a biopharmaceutical research and development company specializing in rare diseases, has signed a collaboration agreement for PHOTOFRIN® with Orphan Canada, a Toronto-based specialty pharmaceutical company that in‐licenses therapies for rare disorders and specialty medicines within Canada.

2 Sep 2014

Neuropsychologist sees increase in ADHD diagnoses

Since 2007, there has been a 16 percent increase in ADHD diagnoses in the United States. While this may alarm some parents, Kids In The House experts explain what this increase really means and how parents can help children who have been diagnosed with ADHD.

2 Sep 2014

Thrombus aspiration for acute myocardial infarction does not reduce mortality

Thrombus aspiration for acute myocardial infarction (AMI) does not reduce mortality or other clinical endpoints long term, according to the awaited one-year follow-up results from the Thrombus Aspiration in ST- Elevation myocardial infarction in Scandinavia (TASTE) trial.

2 Sep 2014

Kids, adolescents are at increased risk of developing diabetes if exposed to antipsychotics

A study published in the September 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that children and adolescents diagnosed with a psychiatric diagnosis had an increased risk of developing diabetes if they were exposed to antipsychotics.

2 Sep 2014

FFR guided drug-eluting stenting reduces death compared to medical therapy in stable CAD patients

Fractional flow reserve (FFR)-guided drug-eluting stenting reduces death, myocardial infarction or urgent revascularisation, as compared to medical therapy in patients with stable coronary artery disease (CAD), according to the results of the FAME 2 trial presented for the first time today at ESC Congress by principal investigator Dr Bernard De Bruyne (Belgium).

2 Sep 2014

Finding could lead researchers to better understand development of psychiatric disorders

Some people take stress in stride; others are done in by it. New research at Rockefeller University has identified the molecular mechanisms of this so-called stress gap in mice with very similar genetic backgrounds - a finding that could lead researchers to better understand the development of psychiatric disorders such as anxiety and depression.

2 Sep 2014

Ambulance administration of antiplatelet medication may help heart attack patients

Ambulance administration of the antiplatelet medication ticagrelor to patients with a type of heart attack known as ST segment elevation myocardial infarction (STEMI) is not better than hospital administration, in terms of improving blood flow in blocked arteries before a revascularisation procedure, according to a new study presented at ESC Congress 2014 today.

2 Sep 2014

Inhaled nitric oxide given to heart attack patients may improve recovery

Inhaled nitric oxide, delivered to heart attack patients before and during treatment with percutaneous coronary intervention (PCI) did not reduce the extent of damaged tissue (infarct), but may have improved recovery, according to Hot Line results presented today at ESC Congress 2014.

2 Sep 2014

Digoxin drug increases risk of adverse cardiovascular events or sudden death

Digoxin may increase the risk of death in patients with atrial fibrillation (AF) by approximately 20%, according to results from the ROCKET AF trial presented at ESC Congress today by Dr Manesh Patel, director of interventional cardiology and catheterisation labs at Duke University Health System in Durham, North Carolina, US.

2 Sep 2014

Simple awareness campaign in general practice helps improve early diagnosis of AF

A simple awareness campaign in general practice identifies new cases of atrial fibrillation (AF), according to research presented at ESC Congress today by Professor Jean-Marc Davy from France.

2 Sep 2014

Permanent atrial fibrillation twins risk of stroke than paroxysmal AF

Permanent atrial fibrillation (AF) doubles the risk of stroke compared to paroxysmal AF, according to research in more than 6 000 patients presented at ESC Congress today by Dr Thomas Vanassche from Belgium. The findings suggest that a simple clinical assessment of the type of AF can help doctors to better estimate stroke risk.

2 Sep 2014

Low-carb trumps low-fat for weight loss and cardiovascular risk

A low-carbohydrate diet is more effective for weight loss and reducing cardiovascular risk factors than a low-fat diet, according to an article being published in Annals of Internal Medicine.

2 Sep 2014

Daily fruit consumption reduces risk of cardiovascular disease by up to 40%

Daily fruit consumption cuts the risk of cardiovascular disease (CVD) by up to 40%, according to research presented at ESC Congress today by Dr Huaidong Du from Oxford, UK.

2 Sep 2014

Abdominal fat more strongly associated with high blood pressure risk

People with fat around their abdominal area are at greater risk of developing hypertension when compared to those with similar body mass index but fat concentrations elsewhere on the body, according to a study published today in the Journal of the American College of Cardiology.

2 Sep 2014

Experimental agent TRO40303 ineffective in patients with heart attack

The administration of an experimental agent known as TRO40303 to patients who have had a heart attack, with the hope of preventing tissue damage when impaired blood flow is corrected (reperfusion), was disappointingly ineffective according to results of a European study of patients with acute ST-elevation myocardial infarction (STEMI) presented today as a Hot Line the ESC Congress 2014 with simultaneous publication in the European Heart Journal.

1 Sep 2014

Alirocumab drug significantly improves cholesterol levels compared to ezetimibe

The investigational drug alirocumab significantly improved cholesterol levels compared to ezetimibe, when added to regular statin therapy in patients with high cholesterol and elevated risk of cardiovascular disease (CVD), according to the ODYSSEY COMBO II trial, presented as a Hot Line today at ESC Congress 2014.

1 Sep 2014

Obese boys are at 6 fold increased risk of hypertension compared to normal weight boys

Obese youths have a nearly six fold risk of hypertension, according to research in more than 22 000 young people from the PEP Family Heart Study presented at ESC Congress today by Professor Peter Schwandt from Germany.

1 Sep 2014

Medical Condition News

Amgen seeks EMA approval for marketing talimogene laherparepvec

MEI Pharma completes patient enrollment in Pracinostat Phase II trial for treatment of MDS

Coffee increases risk of prediabetes in young adults with hypertension

Concordia's subsidiary signs collaboration deal with Orphan Canada for PHOTOFRIN

Neuropsychologist sees increase in ADHD diagnoses

Thrombus aspiration for acute myocardial infarction does not reduce mortality

Kids, adolescents are at increased risk of developing diabetes if exposed to antipsychotics

FFR guided drug-eluting stenting reduces death compared to medical therapy in stable CAD patients

Finding could lead researchers to better understand development of psychiatric disorders

Ambulance administration of antiplatelet medication may help heart attack patients

Inhaled nitric oxide given to heart attack patients may improve recovery

Digoxin drug increases risk of adverse cardiovascular events or sudden death

Simple awareness campaign in general practice helps improve early diagnosis of AF

Permanent atrial fibrillation twins risk of stroke than paroxysmal AF

Low-carb trumps low-fat for weight loss and cardiovascular risk

Daily fruit consumption reduces risk of cardiovascular disease by up to 40%

Abdominal fat more strongly associated with high blood pressure risk

Experimental agent TRO40303 ineffective in patients with heart attack

Alirocumab drug significantly improves cholesterol levels compared to ezetimibe

Obese boys are at 6 fold increased risk of hypertension compared to normal weight boys

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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