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Heroin-assisted treatments benefit some drug users

Drug users who do not benefit from conventional treatments for heroin addiction should be able to access the drug through the health system, urges a Canadian expert in The BMJ today.

16 Apr 2015

Itraconazole drug shows potential in cancer treatment

A common anti-fungal treatment has joined the ranks of drugs that may be suitable for use in treating cancer, according to research from the Repurposing Drugs in Oncology (ReDO) project published in ecancermedicalscience.

16 Apr 2015

New research links megalin protein with malignant melanomas

Today it is not possible to predict spreading from malignant melanomas. Melanoma metastases are furthermore extremely difficult to eliminate as traditional treatment such as chemotherapy and radiotherapy is mostly ineffective. Only ten per cent of the patients survive once they reach an advanced stage with distant metastases.

16 Apr 2015

Novel findings may hold promise for children, adults with mitochondrial disorders

Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in microscopic worms may hold great promise for children and adults with mitochondrial disorders

16 Apr 2015

SGK1 enzyme protects brain cells in animal models of Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have found how a widely known but little-studied enzyme protects brain cells in models of Parkinson's disease.

16 Apr 2015

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

Researchers have begun enrolling participants in a multicenter international clinical trial to test whether statin administration can reduce the risk for major adverse cardiovascular events, such as heart attacks, strokes, and heart disease, in people with HIV infection. The trial is supported by the National Institutes of Health's National Heart, Lung, and Blood Institute and National Institute of Allergy and Infectious Diseases.

16 Apr 2015

Houston Methodist researchers discover new, ex vivo lung cancer model to study tumor progression

Without good models to study cancer metastasis -- the spread of cancer cells from one organ to another -- cancer researchers have struggled to understand tumor progression fully, and new therapies targeting the main causes of death are slow to come.

16 Apr 2015

New Forsyth Institute study sheds light on connection between the mouth and heart

A new study from the Forsyth Institute is helping to shed more light on the important connection between the mouth and heart. According to research recently published online by the American Heart Association, scientists at Forsyth and Boston University have demonstrated that using an oral topical remedy to reduce inflammation associated with periodontitis, more commonly known as gum disease, also results in the prevention of vascular inflammation and can lower the risk of heart attack.

15 Apr 2015

Changes in JAK/STAT3 cell signaling pathway drive ALK-negative ALCL

The first-ever systematic study of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a particularly aggressive form of non-Hodgkin's lymphoma, shows that many cases of the disease are driven by alterations in the JAK/STAT3 cell signaling pathway.

15 Apr 2015

Ancient natural compound can protect the heart from hypertrophy

A natural compound derived from the bark of the magnolia tree, can protect the heart from hypertrophy, a thickening of cardiac muscle often caused by chronic high blood pressure that can lead to heart failure, researchers report in the April 14 issue of the online journal Nature Communications.

15 Apr 2015

Pivotal enters into sales, distribution agreement for BeneFishial family of products

Pivotal Therapeutics Inc., a specialty pharmaceutical company with a focus on Omega-3 therapies for cardiovascular disease and overall health, announced today that it has entered into a Memorandum of Understanding with Korea Animal Medical Science Institute and its newly created affiliate for the exclusive sales and distribution of the BeneFishial family of products.

15 Apr 2015

Study: Children with type 1 diabetes five times more likely to be admitted to hospital

Children living with type 1 diabetes are nearly five times more likely to be admitted to hospital than non-diabetic children, a new study (attached) has found.

15 Apr 2015

Innovative liver cancer treatment gets EU approval

A new treatment for liver cancer developed by the University Medical Center (UMC) Utrecht has received the European CE mark for quality and safety.

15 Apr 2015

Cardio3 BioSciences announces first patient enrollment in NKG2D CAR T-Cell Phase I clinical trial

Cardio3 BioSciences (C3BS), a leader in engineered cell-therapy treatments with clinical programs initially targeting indications in cardiovascular disease and oncology, today announced the enrollment of the first patient in a Phase I clinical trial evaluating the Company’s lead CAR T-Cell therapy, NKG2D CAR T-Cell, in blood cancer patients with acute myeloid leukemia (AML) or multiple myeloma (MM).

15 Apr 2015

Johns Hopkins researchers create the largest library of brain cells from ALS patients

Researchers at Johns Hopkins Medicine have transformed skin cells from patients with Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), into brain cells affected by the progressive, fatal disease and deposited those human-made cells into the first public ALS cell library, enabling scientists to better study the disease.

15 Apr 2015

Experts to make roadmap for future research, clinical trials for SCLC patients at IASLC workshop

Small cell lung cancer (SCLC) will be the concentrated focus when 100 global experts in the field meet for a workshop hosted by the International Association for the Study of Lung Cancer on April 22-24, 2015 at Memorial Sloan Kettering Cancer Center in New York City.

15 Apr 2015

New research could transform treatments for patients with Barrett's Oesophagus

New research from the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust could transform treatments and diagnosis for a common digestive condition which affects thousands of patients.

15 Apr 2015

Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

Haag-Streit Surgical receives FDA 510(k) clearance for intraoperative-OCT camera

HAAG-STREIT SURGICAL announced its intraoperative-OCT camera has received 510(k) clearance from the U.S. Food and Drug Administration for marketing on the largest medical device market in the world.

15 Apr 2015

New longer-term data on Genzyme's relapsing MS treatments to be presented at AAN 2015

Genzyme, a Sanofi company, announced today that new longer-term data on its relapsing multiple sclerosis treatments, Aubagio (teriflunomide) and Lemtrada (alemtuzumab), will be featured during the 67th annual meeting of the American Academy of Neurology being held in Washington, D.C. April 18-25.

15 Apr 2015

Medical Condition News

Heroin-assisted treatments benefit some drug users

Itraconazole drug shows potential in cancer treatment

New research links megalin protein with malignant melanomas

Novel findings may hold promise for children, adults with mitochondrial disorders

SGK1 enzyme protects brain cells in animal models of Parkinson's disease

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

Houston Methodist researchers discover new, ex vivo lung cancer model to study tumor progression

New Forsyth Institute study sheds light on connection between the mouth and heart

Changes in JAK/STAT3 cell signaling pathway drive ALK-negative ALCL

Ancient natural compound can protect the heart from hypertrophy

Pivotal enters into sales, distribution agreement for BeneFishial family of products

Study: Children with type 1 diabetes five times more likely to be admitted to hospital

Innovative liver cancer treatment gets EU approval

Cardio3 BioSciences announces first patient enrollment in NKG2D CAR T-Cell Phase I clinical trial

Johns Hopkins researchers create the largest library of brain cells from ALS patients

Experts to make roadmap for future research, clinical trials for SCLC patients at IASLC workshop

New research could transform treatments for patients with Barrett's Oesophagus

Genetically modified Salmonella can help kill cancer cells

Haag-Streit Surgical receives FDA 510(k) clearance for intraoperative-OCT camera

New longer-term data on Genzyme's relapsing MS treatments to be presented at AAN 2015

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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