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LSDF announces $1.2 million in grants to foster advancement of promising health-related technologies

The Life Sciences Discovery Fund today announced $1.2 million in Proof of Concept grants to Washington-based organizations to foster the advancement of promising health-related technologies to commercial products. Also announced were two commercialization-focused awards, totaling $600,000, through a new funding program requiring external cash matching.

18 Dec 2014

Findings show effective treatment for type 1 diabetes patients with severe hypoglycemia

Type 1 diabetes (T1D) patients who have developed low blood sugar (hypoglycemia) as a complication of insulin treatments over time are able to regain normal internal recognition of the condition after receiving pancreatic islet cell transplantation, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania, published online in Diabetes.

18 Dec 2014

TUM researchers discover new mechanism for regulating programmed cell death

Programmed cell death is a mechanism that causes defective and potentially harmful cells to destroy themselves. It serves a number of purposes in the body, including the prevention of malignant tumor growth. Now, researchers at Technische Universität München have discovered a previously unknown mechanism for regulating programmed cell death.

18 Dec 2014

Researchers treat myocardial infarction with new telomerase-based gene therapy

The enzyme telomerase repairs cell damage produced by ageing, and has been used successfully in therapies to lengthen the life of mice. Now it has been observed that it could also be used to cure illnesses related to the ageing process.

18 Dec 2014

CF patients require close monitoring for resistance to ganciclovir after lung transplantation

A drug called ganciclovir is given to lung transplant patients to protect against a life-threatening virus that is common after transplantation.

18 Dec 2014

Brandeis University researchers capture highest resolution images of cilia ever

Cilia, the cell's tails and antennas, are among the most important biological structures. They line our windpipe and sweep away all the junk we inhale; they help us see, smell and reproduce. When a mutation disrupts the function or structure of cilia, the effects on the human body are devastating and sometimes lethal.

18 Dec 2014

U-M researchers devise reliable way to grow tumor cells

In a development that could lead to a deeper understanding of cancer and better early-stage treatment of the disease, University of Michigan researchers have devised a reliable way to grow a certain type of cancer cells from patients outside the body for study.

18 Dec 2014

Kaiser Permanente study: Self-reported exercise lowers blood pressure, blood glucose levels

Self-reported moderate to vigorous exercise was associated with lower blood pressure and blood glucose levels in a Kaiser Permanente study published in the journal Preventing Chronic Disease.

18 Dec 2014

$Nuvo Research completes WF10 Phase 2 trial in patients with refractory allergic rhinitis$

Nuvo Research completes WF10 Phase 2 trial in patients with refractory allergic rhinitis

Nuvo Research Inc., a specialty pharmaceutical company with a diverse portfolio of immunology and topical products, today announced that 179 patients have completed its 16-week, double-blind, placebo-controlled, Phase 2 clinical trial to investigate the safety and efficacy of WF10 in patients with refractory allergic rhinitis.

18 Dec 2014

SPECT scan measures brain activity during seizures

Loyola University Medical Center is offering epileptic patients an imaging scan that records brain activity during seizures.

18 Dec 2014

Eating bilberries reduces adverse effects of high-fat diets

Eating bilberries diminishes the adverse effects of a high-fat diet, according to a recent study at the University of Eastern Finland. For the first time, bilberries were shown to have beneficial effects on both blood pressure and nutrition-derived inflammatory responses.

18 Dec 2014

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Inovio Pharmaceuticals, Inc. announced it has initiated a phase I trial of its hTERT DNA immunotherapy (INO-1400) alone or in combination with Inovio's IL-12 immune activator (INO-9012) in adults with breast, lung, or pancreatic cancer at high risk of relapse after surgery and other cancer treatments.

18 Dec 2014

Columbia University researchers analyze results of Oregon Health Experiment

Researchers at Columbia University's Mailman School of Public Health analyzed the results of the Oregon Health Experiment, where eligible uninsured individuals were randomly assigned Medicaid or to stay with their current care. Considered controversial because the experiment found no measurable gains for physical health it did reveal benefits for mental health, financial wellbeing, and preventive screening.

18 Dec 2014

Researchers examine why Mexican-Americans at increased risk for Type 2 diabetes

While people of Mexican ancestry are nearly twice as likely to develop Type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin.

18 Dec 2014

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

18 Dec 2014

Laparoscopic radical cystectomy can lead to reliable, long-term cancer control

Long-term survival rates following laparoscopic surgery for bladder cancer are comparable to those of open surgery, according to a study published in BJU International. The findings, which come from the largest study to date with long-term follow-up after this type of minimally invasive surgery, indicate that prospective randomized trials comparing these two bladder cancer surgeries are warranted.

18 Dec 2014

Research findings may lead to new treatment strategies for Ewing sarcoma

The genetic abnormality that drives the bone cancer Ewing sarcoma operates through two distinct processes - both activating genes that stimulate tumor growth and suppressing those that should keep cancer from developing. These findings by Massachusetts General Hospital investigators, published in the November issue of Cancer Cell, may lead to new therapies targeting these aberrant mechanisms.

18 Dec 2014

Sugar-based molecular microcapsule eliminates toxicity of anticancer agent

Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human pancreatic cancer tissue. The encapsulated drug packed a potent anticancer punch, stopping the progression of tumors in the mice, but without the usual toxic effects.

18 Dec 2014

AAN urges for more research on use of medical marijuana for brain, nervous system disorders

The American Academy of Neurology is calling for more research on the use of medical marijuana for brain, spine and nervous system disorders in a new position statement released by the AAN, the world's largest association of neurologists with more than 28,000 members.

18 Dec 2014

Loyola neurologist finds little scientific evidence that brain games improve cognitive function

Computerized brain games that are advertised as a way to help boost intelligence and prevent dementia will be popular Christmas gifts this year.

18 Dec 2014

Medical Condition News

LSDF announces $1.2 million in grants to foster advancement of promising health-related technologies

Findings show effective treatment for type 1 diabetes patients with severe hypoglycemia

TUM researchers discover new mechanism for regulating programmed cell death

Researchers treat myocardial infarction with new telomerase-based gene therapy

CF patients require close monitoring for resistance to ganciclovir after lung transplantation

Brandeis University researchers capture highest resolution images of cilia ever

U-M researchers devise reliable way to grow tumor cells

Kaiser Permanente study: Self-reported exercise lowers blood pressure, blood glucose levels

Nuvo Research completes WF10 Phase 2 trial in patients with refractory allergic rhinitis

SPECT scan measures brain activity during seizures

Eating bilberries reduces adverse effects of high-fat diets

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Columbia University researchers analyze results of Oregon Health Experiment

Researchers examine why Mexican-Americans at increased risk for Type 2 diabetes

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Laparoscopic radical cystectomy can lead to reliable, long-term cancer control

Research findings may lead to new treatment strategies for Ewing sarcoma

Sugar-based molecular microcapsule eliminates toxicity of anticancer agent

AAN urges for more research on use of medical marijuana for brain, nervous system disorders

Loyola neurologist finds little scientific evidence that brain games improve cognitive function

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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