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Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.

26 May 2014

Mice with 'mohawk hairstyles' reveal clues to development of autism

"Aha" moments are rare in medical research, scientists say. As rare, they add, as finding mice with Mohawk-like hairstyles.

26 May 2014

Researchers discover signaling pathway in cancer cells that invades nearby tissues

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a signaling pathway in cancer cells that controls their ability to invade nearby tissues in a finely orchestrated manner.

26 May 2014

Study: Sufficient copies of SMN1 gene extend survival in animals with spinal muscular atrophy

To make up for insufficient amounts of SMN protein, the cause of the inherited neuromuscular disease spinal muscular atrophy (SMA), researchers have successfully delivered a replacement SMN1 gene directly to the spinal cords of animal models of SMA.

23 May 2014

Research reveals pattern of neurocognitive risks in children with cochlear implants

Children with profound deafness who receive a cochlear implant had as much as five times the risk of having delays in areas of working memory, controlled attention, planning and conceptual learning as children with normal hearing, according to Indiana University research published May 22 in the Journal of the American Medical Association Otolaryngology--Head and Neck Surgery.

23 May 2014

EMA's CHMP gives positive opinion for PTC Therapeutics' Translarna

PTC Therapeutics, Inc. today announced that following its request for re-examination, the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion regarding the company's application for a conditional marketing authorization of Translarna (ataluren) for the treatment of nonsense mutation Duchenne muscular dystrophy (nmDMD) in ambulatory patients aged five years and older.

23 May 2014

World Health Assembly approves resolution on viral hepatitis and noncommunicable diseases

The World Health Assembly approved a resolution to improve the prevention, diagnosis and treatment of viral hepatitis and proposals to improve global coordination of efforts to address noncommunicable diseases like diabetes, cancers, heart disease and stroke. In addition, WHO's Director-General and the President of the Health Assembly presented 4 awards to leaders in public health.

23 May 2014

Researchers identify chemical signals that promote breast cancer metastasis

Working with mice, Johns Hopkins researchers report they have identified chemical signals that certain breast cancers use to recruit two types of normal cells needed for the cancers' spread.

23 May 2014

European Commission grants Marketing Authorization for empagliflozin for treatment of type 2 diabetes

The European Commission has granted Marketing Authorisation for empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor from Boehringer Ingelheim and Eli Lilly and Company.

23 May 2014

Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers have discovered how a gene commonly linked to obesity—FTO—contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells.

23 May 2014

Study shows how gender, age and place of residence influence depressive symptoms among older people

Residents of the Italian island of Sardinia are known for their longevity. Now, a new study also shows that elderly Sardinians are less depressed and generally are in a better mental frame of mind than peers living elsewhere.

23 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

Eliminating scar tissue, inflammation may make tumors more deadly, find researchers

New research represents a significant change in the understanding of how pancreatic cancer grows - and how it might be defeated.

23 May 2014

Obesity epidemic strikes all groups of Americans

The nation's obesity epidemic is striking all groups of Americans, affecting those with more education and those with less education, as well as all ethnic groups, according to a new analysis that challenges prevailing assumptions about the reasons why the nation is getting heavier.

23 May 2014

New report raises important questions about transcranial direct current stimulation

Over the past several decades, neurostimulation techniques such as transcranial direct current stimulation (tDCS) have gradually gained favour in the public eye. In a new report, published yesterday in the prestigious scientific journal Neuron, IRCM ethics experts raise important questions about the rising tide of tDCS coverage in the media, while regulatory action is lacking and ethical issues need to be addressed.

23 May 2014

Common explanations for rising obesity rates are simply wrong, say researchers

Everything you think you know about the causes of rising obesity in the U.S. might be wrong, researchers say in a new report.

23 May 2014

Study shows disparity between US and English discharge rates for pediatric bipolar

A study published in the June 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found a very much higher discharge rate for pediatric bipolar (PBD) in children and adolescents aged 1-19 years in the US compared to England between the years 2000-2010.

23 May 2014

American Association of Diabetes Educators suggests tips for safe travel

AAA estimates 36.1 million people will travel this Memorial Day weekend. If diabetes is your constant companion, that doesn't mean you can't enjoy traveling, whether traversing America in an RV or flying to the far reaches of the globe. Ensuring you stay healthy and keep your glucose levels on an even keel does require a little bit of organization and planning ahead, though.

23 May 2014

Cheap food plays key role in rising obesity epidemic

A new review summarizes what is known about economic factors tied to the obesity epidemic in the United States and concludes many common beliefs are wrong.

23 May 2014

New database allows researchers to match old drugs for new diseases

There are thousands of drugs that silence many thousands of cancer-causing genetic abnormalities. Some of these drugs are in use now, but many of these drugs are sitting on shelves or could be used beyond the disease for which they were originally approved.

23 May 2014

Medical Condition News

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Mice with 'mohawk hairstyles' reveal clues to development of autism

Researchers discover signaling pathway in cancer cells that invades nearby tissues

Study: Sufficient copies of SMN1 gene extend survival in animals with spinal muscular atrophy

Research reveals pattern of neurocognitive risks in children with cochlear implants

EMA's CHMP gives positive opinion for PTC Therapeutics' Translarna

World Health Assembly approves resolution on viral hepatitis and noncommunicable diseases

Researchers identify chemical signals that promote breast cancer metastasis

European Commission grants Marketing Authorization for empagliflozin for treatment of type 2 diabetes

Researchers discover how gene commonly linked to obesity contributes to weight gain

Study shows how gender, age and place of residence influence depressive symptoms among older people

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Eliminating scar tissue, inflammation may make tumors more deadly, find researchers

Obesity epidemic strikes all groups of Americans

New report raises important questions about transcranial direct current stimulation

Common explanations for rising obesity rates are simply wrong, say researchers

Study shows disparity between US and English discharge rates for pediatric bipolar

American Association of Diabetes Educators suggests tips for safe travel

Cheap food plays key role in rising obesity epidemic

New database allows researchers to match old drugs for new diseases

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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