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Early life chronic stress may cause anxiety in adulthood, says study

In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior - both at the time that stress is experienced, and upon the same individuals later in life, during adulthood.

28 Mar 2014

American College of Cardiology honors two Cedars-Sinai Heart Institute researchers

Two Cedars-Sinai Heart Institute physician-researchers have been named recipients of prestigious awards from the American College of Cardiology.

28 Mar 2014

Takeda to present results from global EXAMINE CV safety outcomes trial at ACC 2014

Takeda Pharmaceuticals Company Limited will present sub-analyses from the global EXAMINE (EXamination of CArdiovascular OutcoMes: AlogliptIN vs. Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome) cardiovascular (CV) safety outcomes trial in a poster session at the American College of Cardiology’s 63rd Annual Scientific Session in Washington, DC.

28 Mar 2014

Researchers find new drug target for mitochondrial dysfunction

Mitochondria, long known as "cellular power plants" for their generation of the key energy source adenosine triphosphate (ATP), are essential for proper cellular functions. Mitochondrial defects are often observed in a variety of diseases, including cancer, Alzheimer's disease, and Parkinson's disease, and are the hallmarks of a number of genetic mitochondrial disorders whose manifestations range from muscle weakness to organ failure. Despite a fairly strong understanding of the pathology of such genetic mitochondrial disorders, efforts to treat them have been largely ineffective.

28 Mar 2014

NARSAD grants to fund research into psychiatric illness by 40 mid-career scientists

The Brain & Behavior Research Foundation today announced its 2014 NARSAD Independent Investigator Grants, which will award $4 million in funding to 40 mid-career scientists from 33 institutions in nine countries. Selected by the Foundation's Scientific Council, comprised of 146 leading experts across disciplines in brain and behavior research including two Nobel Prize winners, the grants fund basic research, new technologies and next generation therapies for schizophrenia, major affective disorders, and other serious mental illnesses.

28 Mar 2014

$Patrys reports final results from PAT-SM6 Phase I/IIa study in patients with refractory or relapsed MM$

Patrys reports final results from PAT-SM6 Phase I/IIa study in patients with refractory or relapsed MM

Patrys Limited, a clinical stage biotechnology company, is pleased to announce the final results from its Phase I/IIa, open-label study in patients with refractory or relapsed multiple myeloma (MM).

28 Mar 2014

Research findings help explain rare genetic disorder that causes immunodeficiency syndrome

IRCM researchers led by Javier M. Di Noia, PhD, uncovered a new function of AID, a crucial enzyme for the immune response. The discovery, recently published by the scientific journal Proceedings of the National Academy of Sciences, helps explain a rare genetic disorder that causes an immunodeficiency syndrome.

28 Mar 2014

Heart attack survival rates lag behind in the South despite overall improvements nationwide

Although heart attack death has declined across all regions of the United States, it is proportionately higher in the South, possibly related to the uneven distribution of socioeconomic and traditional cardiovascular risk factors, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

New research reveals how good sleep can help chronic pain sufferers

Chronic pain sufferers could be kept physically active by improving the quality of their sleep, new research suggests.

28 Mar 2014

Australia's Generation X may overtake Baby Boomers for poor health, say researchers

Researchers at the University of Adelaide have confirmed that if current trends continue, Australia's Generation X will overtake Baby Boomers for poor health, including rates of obesity and diabetes, which could have huge implications for healthcare and the workforce.

28 Mar 2014

Lower levels of vitamin D predict extent of coronary artery disease

Vitamin D deficiency is an independent risk factor for heart disease with lower levels of vitamin D being associated with a higher presence and severity of coronary artery disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Some people experience worse cholesterol levels during colder months

Cholesterol levels fluctuate based on the time of year with more unfavorable lipid profiles seen in the colder months, a trend that may be driven by related behavior changes, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

'Mini heart' invented to aid blood flow through venous segments

George Washington University researcher Narine Sarvazyan, Ph.D., has invented a new organ to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient's own adult stem cells, eliminating the chance of implant rejection.

28 Mar 2014

IRB researchers identify dual role of p38 protein in colon cancer

A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine identifies a dual role of the p38 protein in colon cancer. The study demonstrates that, on the one hand, p38 is important for the optimal maintenance of the epithelial barrier that protects the intestine against toxic agents, thus contributing to decreased tumour development.

28 Mar 2014

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

Heart failure patients benefit from new device till transplant

The largest single-center study of patients implanted with a total artificial heart finds the device may help patients in severe heart failure survive until they can receive a heart transplant, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

The National Cancer Institute has awarded a three-year grant totaling $2,168,535 to Professor Yijun Ruan, Ph.D., of The Jackson Laboratory for Genomic Medicine, for his research into the role of noncoding RNAs in cancer and other diseases.

28 Mar 2014

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

An international team of researchers, led by Beaumont Health System's Jan Akervall, M.D., Ph.D., looked at biomarkers to determine the effectiveness of radiation treatments for patients with squamous cell cancer of the head and neck.

28 Mar 2014

Study links broken heart syndrome to natural disasters

Dramatic spikes in cases of Takotsubo cardiomyopathy, also called broken heart syndrome, were found in two states after major natural disasters, suggesting the stress of disasters as a likely trigger, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Medical Condition News

Early life chronic stress may cause anxiety in adulthood, says study

American College of Cardiology honors two Cedars-Sinai Heart Institute researchers

Takeda to present results from global EXAMINE CV safety outcomes trial at ACC 2014

Researchers find new drug target for mitochondrial dysfunction

NARSAD grants to fund research into psychiatric illness by 40 mid-career scientists

Patrys reports final results from PAT-SM6 Phase I/IIa study in patients with refractory or relapsed MM

Research findings help explain rare genetic disorder that causes immunodeficiency syndrome

Heart attack survival rates lag behind in the South despite overall improvements nationwide

New research reveals how good sleep can help chronic pain sufferers

Australia's Generation X may overtake Baby Boomers for poor health, say researchers

Lower levels of vitamin D predict extent of coronary artery disease

Some people experience worse cholesterol levels during colder months

'Mini heart' invented to aid blood flow through venous segments

IRB researchers identify dual role of p38 protein in colon cancer

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Discovery could lead to new medications for cancer, say Rice University scientists

Heart failure patients benefit from new device till transplant

Jackson Lab professor wins nearly $2M grant for investigating role of noncoding RNAs in cancer

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

Study links broken heart syndrome to natural disasters

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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