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Astellas seeks regulatory approval for mirabegron to treat overactive bladder in the U.S., Europe

Astellas Pharma Inc. today announced the submission of a New Drug Application and Market Authorisation Application for mirabegron to the U.S. Food and Drug Administration and the European Medicines Agency.

29 Aug 2011

Apixaban superior to warfarin in preventing stroke and systemic embolism

A large-scale trial finds that apixaban, a new anticoagulant drug, is superior to the standard drug warfarin for preventing stroke and systemic embolism in patients with atrial fibrillation.

29 Aug 2011

New research: Inattention associated with educational failure

New research from the University of Montreal shows that inattention, rather than hyperactivity, is the most important indicator when it comes to finishing a high school education.

29 Aug 2011

Researchers identify molecule that can stop the formation of amyloid fibrils

A molecule which can stop the formation of long protein strands, known as amyloid fibrils, that cause joint pain in kidney dialysis patients has been identified by researchers at the University of Leeds.

29 Aug 2011

FDA approves Abbott's Vysis ALK FISH test for NSCLC therapy selection

Abbott today announced it has received approval from the U.S. Food and Drug Administration (FDA) for a new molecular diagnostic test designed to detect rearrangements of the anaplastic lymphoma kinase (ALK) gene in non-small-cell lung cancer.

29 Aug 2011

'Electronic nose' smells heart failure

A German team has developed a completely new non-invasive method to identify heart failure. It consists of an "electronic nose" which could make the "smelling" of heart failure possible. The projet was presented at the ESC Congress 2011 today.

29 Aug 2011

Pfizer receives FDA approval for XALKORI capsules to treat ALK-positive NSCLC

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved XALKORI (crizotinib) capsules, the first-ever therapy targeting anaplastic lymphoma kinase (ALK), for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) that is ALK-positive as detected by an FDA-approved test.

29 Aug 2011

Azithromycin can help reduce wheezing, other acute symptoms of COPD

A common antibiotic can help reduce the severe wheezing and other acute symptoms of chronic obstructive pulmonary disease, according to a large, multicenter clinical trial sponsored by the National Institutes of Health and conducted at the University of California, San Francisco (UCSF).

29 Aug 2011

Severe combined immunodeficiency treated successfully with gene therapy

Gene therapy can offer a cure for a rare condition that causes children’s immune systems to fail. In this rare condition, known as Severe Combined Immunodeficiency (SCID), inherited genetic mutations mean that babies are unable to fight off infection, severely limiting their chances of surviving more than a few years. Severe combined immunodeficiency (SCID) is a rare genetic disorder estimated to affect between 1 in 200,000 and 1 in 1,000,000 live births

26 Aug 2011

New imaging device enables scientists to see tumor cells traveling in the brain

For the first time, scientists can see pathways to stop a deadly brain cancer in its tracks. Researchers at Case Western Reserve University School of Medicine have imaged individual cancer cells and the routes they travel as the tumor spreads.

26 Aug 2011

ESC introduces update to HeartScore application

The number of heart attack and stroke incidents in Europe is likely to reduce with the imminent launch of an update to the HeartScore® application. HeartScore® was first developed by the European Society of Cardiology (ESC) in 2004, and it helps clinicians rapidly estimate the risk of cardiovascular disease (CVD) in individual patients using age, gender, basic health indicators, and lifestyle factors.

26 Aug 2011

IOM report: Vaccines generally safe, no link to autism

Vaccines can cause certain side effects but serious ones appear very rare - and there's no link with autism and Type 1 diabetes, the Institute of Medicine says in the first comprehensive safety review in 17 years. The report released Thursday isn't aimed at nervous parents. And the side effects it lists as proven are some that doctors long have known about, such as fever-caused seizures and occasional brain inflammation.

26 Aug 2011

Global obesity rates doubled over last 30 years, researchers say

"Obesity rates worldwide have doubled in the last three decades, even as blood pressure and cholesterol levels have dropped," according to a series of papers published Friday in the Lancet, the Associated Press/New York Times reports (8/25).

26 Aug 2011

New ESC Guidelines on diagnosis and treatment of peripheral artery disease

For cardiologists, coronary artery disease is the most important presentation of atherosclerosis. Patients with coronary artery disease may also have symptomatic or asymptomatic atherosclerosis in other vascular areas (peripheral artery disease).

26 Aug 2011

Risk of coronary heart disease is transferred via genes, not via unhealthy family lifestyle

It has long been known that hereditary factors play a role in coronary heart disease. However, it has been unclear whether the increased risk is transferred through the genes or through an unhealthy lifestyle in the family. A new study from the Center for Primary Health Care Research in Sweden, published in the American Heart Journal, shows that genes appear to be most important.

26 Aug 2011

BIPI to launch dabigatran etexilate Phase II trial in patients with mechanical heart valves

Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) today announced plans to launch RE-ALIGN, a global, Phase II trial evaluating the safety and pharmacokinetics of dabigatran etexilate in 400 patients who have mechanical heart valves.

26 Aug 2011

NIH creates mathematical model to predict weight changes in the body

Researchers at the National Institutes of Health have created a mathematical model - and an accompanying online weight simulation tool - of what happens when people of varying weights, diets and exercise habits try to change their weight. The findings challenge the commonly held belief that eating 3,500 fewer calories - or burning them off exercising - will always result in a pound of weight loss.

26 Aug 2011

SuperSonic Imagine introduces UltraFast Doppler technology

SuperSonic Imagine, the ultrasound company that pioneered breakthrough ShearWave Elastography technology, today announced another major breakthrough in ultrasound imaging: UltraFast Doppler.

26 Aug 2011

Kettering University's biodegradable magnesium alloy can repair traumatic bone injury

Repairing traumatic injury to a bone is possible, but current procedures require multiple surgeries and long-term recovery. Kettering University's Dr. Montserrat Rabago-Smith and her team of co-researchers are exploring the use of a magnesium orthotic alloy in severe trauma injuries where the distance between two halves of a bone can't be overcome by the human body's ability to regenerate and heal.

26 Aug 2011