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Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Older adults without dementia and with lower levels in plasma of the biomarkers beta-amyloid 42/40 (protein fragments) had an increased rate of cognitive decline over a period of 9 years, according to a study in the January 19 issue of JAMA. The researchers also found that this relationship was stronger among individuals with less education and lower levels of literacy.

19 Jan 2011

Study shows physical activity helps people with osteoarthritis to walk faster

When a traffic light at a busy intersection flashes the WALK sign, people with knee osteoarthritis worry they can't walk fast enough to make it across the street in time. New Northwestern Medicine research shows people with this common arthritis are more likely to walk fast enough if they lead physically active lives.

19 Jan 2011

RG7204 Phase III study shows significant survival benefit in patients with metastatic melanoma

Genentech, a member of the Roche Group, today announced that BRIM3, a Phase III clinical study of RG7204, met its co-primary endpoints showing a significant survival benefit in people with previously untreated BRAF V600 mutation-positive metastatic melanoma.

19 Jan 2011

New GORE VIABAHN Endoprosthesis is now available in Europe

W. L. Gore & Associates today announced the European availability of the GORE VIABAHN Endoprosthesis on a lower profile delivery system. The announcement came during the Leipzig Interventional Course in Germany, where European interventionalists gathered to discuss new approaches in treating patients suffering from peripheral artery disease.

19 Jan 2011

Neuroform EZ Stent System helps neurosurgeons to treat brain aneurysms

A new device to treat brain aneurysms with stents improves access to the blood vessels allowing endovascular neurosurgeons to offer the minimally invasive technique to patients with complex cases. Dr. Demetrius Lopes, an endovascular neurosurgeon at Rush University Medical Center, was the first in the U.S. to use the new delivery system, called the Neuroform EZ Stent System.

19 Jan 2011

Positive preliminary results from Soligenix's SGX202 in GARS model

Soligenix, Inc., a late-stage biopharmaceutical company, announced today promising preliminary results from a preclinical study of SGX202 in a canine gastrointestinal acute radiation syndrome model.

19 Jan 2011

Cancer cells brought back under normal control

Scientists at The University of Nottingham have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers.

19 Jan 2011

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease, according to a study in the January 19 issue of JAMA.

19 Jan 2011

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge. Now, new research has identified a common genetic risk factor for heart failure in Caucasians that is also linked to kidney function.

19 Jan 2011

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

The Scripps Research Institute has been awarded $3.17 million over four years to develop compounds that will counteract disruptions of the human biological clock - the circadian rhythm that regulates our patterns of activity and rest over a 24-hour daily cycle.

19 Jan 2011

Higher fruit and vegetable intake lowers risk of dying from ischaemic heart disease

A European study investigating the links between diet and disease has found that people who consume more fruit and vegetables have a lower risk of dying from ischaemic heart disease - the most common form of heart disease and one of the leading causes of death in Europe.

19 Jan 2011

Positive results from PLX4032 Phase 3 Trial in patients with metastatic melanoma

Plexxikon today announced positive data from an interim analysis of the BRIM3 trial, a large multi-center Phase 3 clinical study of PLX4032 in patients with previously untreated metastatic melanoma with the BRAF mutation. Patients treated with PLX4032 had an improved overall survival compared to patients treated with dacarbazine, the current standard of care.

19 Jan 2011

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Watching the brain's "autopilot" network in real time may help determine the onset of cognitive decline and potentially aid in making an early diagnosis of Alzheimer's disease, according to researchers at Duke University Medical Center.

19 Jan 2011

Magnetic maneuverable capsule safe and well-tolerated in the stomach

A study from researchers in Germany showed that magnetic maneuvering of a modified capsule endoscope in the stomach of healthy volunteers under clinical conditions is safe, well-tolerated, and technically feasible. Maneuverability of the capsule within the stomach was excellent and visualization of the gastric mucosa, the inner lining of the stomach, was satisfactory in the majority of subjects.

19 Jan 2011

Medical Condition News

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Study shows physical activity helps people with osteoarthritis to walk faster

RG7204 Phase III study shows significant survival benefit in patients with metastatic melanoma

New GORE VIABAHN Endoprosthesis is now available in Europe

Neuroform EZ Stent System helps neurosurgeons to treat brain aneurysms

Positive preliminary results from Soligenix's SGX202 in GARS model

Cancer cells brought back under normal control

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

Higher fruit and vegetable intake lowers risk of dying from ischaemic heart disease

Positive results from PLX4032 Phase 3 Trial in patients with metastatic melanoma

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Magnetic maneuverable capsule safe and well-tolerated in the stomach

Study may help develop novel ways to combat lipotoxic cardiomyopathy, related heart disease

New findings show reduced vitamin D absorption in patients with quiescent CD

Uric acid levels linked to severe osteoarthritis

MicroRNA-29 molecule makes brain cells resistant to programmed cell death

Research identifies childhood traumatic stress as potential risk factor for obesity in adulthood

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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