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New data on long-term use of antidepressant drugs

There is increasing awareness that, in some cases, long-term use of antidepressant drugs (AD) may enhance the biochemical vulnerability to depression and worsen its long-term outcome and symptomatic expression, decreasing both its likelihood of subsequent response to pharmacological treatment and the duration of symptom-free periods. A review of literature suggesting potential side effects during long treatment with antidepressant drugs was performed.

3 Oct 2011

Health Canada approves Trajenta (linagliptin) for type 2 diabetes

Boehringer Ingelheim Canada and Eli Lilly Canada today announced that Health Canada has approved Trajenta (linagliptin), a new oral therapy to improve glycemic control in Canadian adults with type 2 diabetes.

3 Oct 2011

Alkermes initiates ALKS 37 phase 2b study in opioid-induced constipation

Alkermes plc today announced the initiation of a phase 2b study of ALKS 37, an orally active, peripherally restricted opioid antagonist for the treatment of opioid-induced constipation.

3 Oct 2011

Study sheds new light on relationship of anxiety and high blood pressure to primary aldosteronism

A study that has been published in the Journal of Clinical Endocrinology and Metabolism by an Italian group headed by Nicoletta Sonino (Padova) sheds some new light on the relationship of anxiety and high blood pressure to a hormonal disturbance, primary aldosteronism.

3 Oct 2011

La Jolla Institute scientist identifies previously unknown T cell interaction

Most of the time, the immune system is the body's protector, warding off invading viruses and bacteria before they can lead to infection and disease. But in autoimmune diseases, the immune system does an about face, turning on the body and attacking normal cells.

3 Oct 2011

Vexim obtains registration certificate for SpineJack in India

Vexim, the Med-Tech specialist in the minimally invasive, anatomical treatment of vertebral compression fractures, today announced that it has obtained the registration certificate for SpineJack in India.

3 Oct 2011

Mild stroke patients may live with hidden disabilities: Study

On the surface they appear unaffected, but people who have mild strokes may live with hidden disabilities, including depression, vision problems and difficulty thinking, according to a study released today at the Canadian Stroke Congress.

3 Oct 2011

New research uses Tilman model to study metastasis of prostate cells into bone

The invasion of a new species into an established ecosystem can be directly compared to the steps involved in cancer metastasis. New research published in BioMed Central's open access journal Theoretical Biology and Medical Modelling uses the Tilman model of competition between invasive species to study the metastasis of prostate cells into bone.

3 Oct 2011

Baptist Hospital selects RayStation treatment planning system

RaySearch Laboratories AB has received an order for its RayStation treatment planning system from Baptist Hospital of Miami.

3 Oct 2011

Researchers identify unusual genomic architecture linked with very severe forms of disease

When cells divide normally, DNA gets copied perfectly and distributed among the daughter cells with an even hand. Occasionally though, DNA breaks during division and is rearranged, resulting in duplications or deletions of important parts of the blueprint.

3 Oct 2011

Study compares treatment plans for CyberKnife treatment delivery system

Radiosurgery is a non-invasive medical procedure in which focused beams of high-energy X-rays target tumors and other abnormalities in the body. A single large dose of radiation is capable of ablating a lesion that might not be amenable to surgical removal. However, some radiosurgery systems, such as the CyberKnife (CK), can be relatively time-consuming because the treatment planning requires the delivery of up to several hundred cone-shaped beams to adequately cover an irregularly shaped tumor.

3 Oct 2011

Most people fall after stroke, usually at home: Study

Almost 60 per cent of people who have a stroke experience one or more falls afterwards - most often in their own homes - and some are left with serious injuries, according to a study released today at the Canadian Stroke Congress.

3 Oct 2011

HeartWare announces updated clinical data from BTT study, ADVANCE and CAP

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced updated clinical data from its bridge to heart transplantation (BTT) study, ADVANCE, and the Continued Access Protocol.

3 Oct 2011

EMA accepts Inspiration's IB1001 MAA for treatment of hemophilia B

Inspiration Biopharmaceuticals, Inc. today announced that the European Medicines Agency (EMA) has validated and accepted the filing of the Marketing Authorization Application (MAA) for Inspiration's IB1001, a recombinant factor IX (FIX) product for the treatment and prevention of bleeding in individuals with hemophilia B.

3 Oct 2011

Combination of P16 immunohistochemistry, DNA qPCR can accurately detect oropharyngeal cancer

Researchers have determined that a combination of P16 immunohistochemistry and DNA qPCR to test for viral E6 can accurately determine the oropharyngeal squamous cell carcinoma, a form of head and neck cancer, which derive from HPV16, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

3 Oct 2011

Study: Smokers more likely to develop stroke

Not only are smokers twice as likely to have strokes, they are almost a decade younger than non-smokers when they have them, according to a study presented today at the Canadian Stroke Congress.

3 Oct 2011

Improper footwear may lead to severe foot pain, impairment and disability in gout patients

New research shows that use of poor footwear is common among patients with gout. According to the study published in Arthritis Care & Research, a peer-reviewed journal of the American College of Rheumatology (ACR), gout patients who make poor footwear choices experienced higher foot-related pain, impairment and disability. Gout patients also reported that comfort, fit, support and cost were the most important factors for selecting footwear.

3 Oct 2011

IBA offers full line of Proton Therapy solutions for cancer specialty centers

IBA Particle Therapy now offers a range of Proton Therapy solutions for cancer specialty centers planning to treat from 250 to 2,000 patients annually with protons.

From Elekta 3 Oct 2011

First clinical implementation of RayStation at MGH

RaySearch Laboratories AB announces that the first cancer patient has been treated using a treatment plan created with RaySearch's treatment planning system RayStation. The treatment was carried out at the Massachusetts General Hospital Radiation Oncology Department.

From Elekta 3 Oct 2011

Tight blood sugar control fails to improve memory in diabetics

A new study has shown that those with type 2 diabetes do not show slowing of the decline in thinking skills with intense blood sugar control. In fact such intense therapy raises risk of death.

2 Oct 2011