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CTI announces final pixantrone clinical trial design for treatment of DLBCL

Cell Therapeutics, Inc. today announced the final clinical trial design of a randomized pivotal trial of pixantrone for the treatment of diffuse large B-cell lymphoma following discussions with the U.S. Food and Drug Administration's Division of Hematologic Products.

10 Mar 2011

California leaders completes much-anticipated State Plan for Alzheimer's disease

Anticipating a catastrophic increase in Alzheimer's disease and related dementias, California leaders have completed the much-anticipated California State Plan for Alzheimer's disease, a disease estimated to double among Californians by the year 2030.

10 Mar 2011

CDH Proton Center expands treatment capacity

The CDH Proton Center, A ProCure Center, in suburban Chicago, is now able to treat a wider variety of cancer tumors with the opening of a treatment room with a gantry, a nearly 100-ton rotating steel wheel that allows the proton beam to be directed at the tumor from any angle.

10 Mar 2011

Experimental drug effectively shuts off MCL1 gene and induces apoptosis

Predictive Biomarker Sciences (PBS-Bio) has uncovered how the experimental drug UNBS1450, produced by Unibioscreen, kills cancer cells.

10 Mar 2011

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) may be confined to individuals already at risk because of elevations in a particular inflammatory factor in the blood.

10 Mar 2011

Novel sortase-based techniques allow modification of a large variety of different proteins

Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when administered therapeutically. The technique should be useful to increase potency, slow metabolism, and improve thermal stability of therapeutically useful proteins, such as interferon alpha 2 (IFN-alpha 2), which is used to treat variety of diseases, including leukemia, melanoma, and chronic hepatitis C.

10 Mar 2011

Tiniest pollution particles can contribute to cardiovascular disease in diabetic people

Scientists are untangling how the tiniest pollution particles - which we take in with every breath we breathe - affect our health, making people more vulnerable to cardiovascular and respiratory problems.

10 Mar 2011

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset.

10 Mar 2011

Need for new definition of 'normal' blood pressure

As many as 100 million Americans may currently be misclassified as having abnormal blood pressure, according to Dr. Brent Taylor from the Veterans Affairs Health Care System in Minneapolis and the University of Minnesota and his colleagues. Their findings show that these people are not actually more likely to die prematurely than those with 'normal' blood pressure, i.e. below 120/80.

10 Mar 2011

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Cancer Research Technology and The Institute of Cancer Research have signed a deal with Dutch drug discovery company, ZoBio BV, to discover and develop drugs to block a DNA repair target which may play a role in cancer cell survival.

10 Mar 2011

Medtronic opens new manufacturing facility in Singapore

Medtronic, Inc., the global medical technology leader, announced today the official opening of its new manufacturing facility, Medtronic Singapore Operations. The facility will enhance the company's manufacturing capabilities to meet the future expected growth of cardiac devices in Asia.

10 Mar 2011

Cedars-Sinai earns excellence in 2010 adult heart transplants

The Cedars-Sinai Heart Institute and Comprehensive Transplant Center performed the most adult heart transplants of any U.S. medical center in 2010, according to government statistics released today.

10 Mar 2011

Immunologists identify key cell component that triggers allergic responses to cat dander

A breakthrough by scientists at The University of Nottingham could provide hope for any allergy sufferers who have ever had to choose between their health and their household pet.

10 Mar 2011

Salmonella may serve as valuable tool to fight against cancer

University of Minnesota researchers are using salmonella - the bacteria commonly transmitted through food that sickens thousands of U.S. residents each year - to do what was once unthinkable: help people.

10 Mar 2011

Discovery: Children with severe cerebral palsy have starkly asymmetric pelvic bones

Johns Hopkins Children's Center researchers have discovered that most children with severe cerebral palsy have starkly asymmetric pelvic bones. The newly identified misalignment can affect how surgeries of the pelvis, spine and surrounding structures are performed, the researchers say.

10 Mar 2011

Noninvasive MR-guided focused ultrasound successfully treats essential tremor

A new chapter in medical history opened days ago when noninvasive MR-guided focused ultrasound was used to successfully treat a patient with essential tremor (ET), a progressive neurological disorder that affects millions of people worldwide and causes involuntary shaking of the hands, head, face, eyelids, voice or other muscles.

10 Mar 2011

Health Dialog unveils new Shared Decision Making program for insomnia patients

Health Dialog unveiled today a new Shared Decision Making program titled "Sleeping Better: Help for Long-Term Insomnia," to give patients information they need to make informed treatment decisions for this condition.

10 Mar 2011

FDA informs additional delay of ARYx's request for naronapride SPA

ARYx Therapeutics, Inc. today announced that the US Food and Drug Administration has informed the Company of an additional delay in providing needed guidance on the Phase 3 development of ARYx's product candidate for the treatment of various gastrointestinal disorders, naronapride. In this latest communication with ARYx, the FDA suggests a response will not be forthcoming until July 2011 at the earliest.

10 Mar 2011

Researchers pinpoint a protein responsible for fat storage in the body

Scientists have shed light on why some people are apple-shaped and others are pear-shaped.

10 Mar 2011

Stemline's SL-401 receives FDA Orphan Drug designation for treatment of acute myeloid leukemia

Stemline Therapeutics, Inc. today announced that SL-401, the Company's lead compound, has received Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for the treatment of acute myeloid leukemia (AML).

10 Mar 2011

Medical Condition News

CTI announces final pixantrone clinical trial design for treatment of DLBCL

California leaders completes much-anticipated State Plan for Alzheimer's disease

CDH Proton Center expands treatment capacity

Experimental drug effectively shuts off MCL1 gene and induces apoptosis

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

Novel sortase-based techniques allow modification of a large variety of different proteins

Tiniest pollution particles can contribute to cardiovascular disease in diabetic people

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Need for new definition of 'normal' blood pressure

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Medtronic opens new manufacturing facility in Singapore

Cedars-Sinai earns excellence in 2010 adult heart transplants

Immunologists identify key cell component that triggers allergic responses to cat dander

Salmonella may serve as valuable tool to fight against cancer

Discovery: Children with severe cerebral palsy have starkly asymmetric pelvic bones

Noninvasive MR-guided focused ultrasound successfully treats essential tremor

Health Dialog unveils new Shared Decision Making program for insomnia patients

FDA informs additional delay of ARYx's request for naronapride SPA

Researchers pinpoint a protein responsible for fat storage in the body

Stemline's SL-401 receives FDA Orphan Drug designation for treatment of acute myeloid leukemia

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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