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Inhaled corticosteroids may cause diabetes

In a study published in the most recent issue of The American Journal of Medicine, researchers found that inhaled corticosteroids were associated with a 34% increase in the rate of diabetes onset and in the rate of diabetes progression. At the highest inhaled doses the risk increased by 64% in diabetes onset and 54% in diabetes progression.

15 Dec 2010

Genes predict survival time, potential new treatments for patients with non-small cell lung cancer

Researchers at UT Southwestern Medical Center have discovered sets of genes active in cancer cells and normal tissue that predict survival time and potential new treatments for patients with non-small cell lung cancer.

15 Dec 2010

Hemispherx granted extension to modify Ampligen NDA for CFS indication

Hemispherx Biopharma, Inc. announced today that the Food and Drug Administration (FDA) granted a 12 month extension for the Company to modify its NDA in response to a Complete Response Letter (CRL) received November 25, 2009 for the CFS indication.

15 Dec 2010

Study shows breast inflammation promotes development and progression of cancer

It took 12 years and a creation of a highly sophisticated transgenic mouse, but researchers at Kimmel Cancer Center at Jefferson have finally proven a long suspected theory: Inflammation in the breast is key to the development and progression of breast cancer.

15 Dec 2010

BUSM awarded NCI EDRN, DOD grants to develop novel procedures for early detection of lung cancer

Researchers from Boston University School of Medicine (BUSM) have been awarded a five-year, $2 million grant from the National Cancer Institute (NCI) Early Detection Research Network (EDRN), as well as a four-year, $1.3 million grant from the Department of Defense (DOD). These grants will allow the scientists to develop novel and complementary procedures for early detection of lung cancer in high-risk patients.

15 Dec 2010

DBS targets same class of neuronal cells that respond to physical exercise and drug Prozac

Shooting steady pulses of electricity through slender electrodes into a brain area that controls complex behaviors has proven to be effective against several therapeutically stubborn neurological and neuropsychiatric disorders. Now, a new study has found that this technique, called deep brain stimulation (DBS), targets the same class of neuronal cells that are known to respond to physical exercise and drugs such as Prozac.

15 Dec 2010

New research reports more than 10% of RA patients lack health literacy

Many patients seen at a rheumatology clinic—including some with a long history of rheumatoid arthritis (RA)—don't recognize important terms related to their health and medical treatment, reports a study in the December issue of JCR: Journal of Clinical Rheumatology.

15 Dec 2010

DARA's KRN5500 reduces allodynia in Phase 2a study for neuropathic pain in cancer patients

DARA BioSciences, Inc. announced today additional positive results from its successfully completed KRN5500 Phase 2a Clinical Study for treatment of neuropathic pain in patients with cancer. Statistically significant primary endpoint results were released earlier.

15 Dec 2010

Davita launches online tool for dialysis patients

DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic kidney disease and end stage renal disease, today announced the launch of MyDaVita, an online tool intended to help patients connect with one another for friendship, support and educational information.

15 Dec 2010

UCSF scientists explain why oligodendroglioma is more responsive to therapy than other brain tumors

For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer. A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.

15 Dec 2010

Abbott initiates ABT-806 Phase 1 trial in EGFR expressing tumors

Life Science Pharmaceuticals (LSP) announced today a milestone related to monoclonal-antibody (mAb) 806 licensed to Abbott. A Phase 1 trial with ABT-806, a humanized version of mAb 806 that selectively targets the epidermal growth factor receptor (EGFR), has been initiated by Abbott in the U.S. The trial will assess the safety and pharmacokinetics of ABT-806 in patients with advanced solid tumors likely or known to express EGFR.

15 Dec 2010

Neuropeptide S protein boosts memory

UC Irvine researchers have identified a novel mechanism in the brain that boosts memory.

15 Dec 2010

Study: HUCBs boost survival and maturation of hippocampal neurons

Laboratory culture studies examining the activity of human umbilical cord blood cells on experimental models of central nervous system aging, injury and disease, have shown that HUCBs provide a 'trophic effect' that enhances survival and maturation of hippocampal neurons harvested from both young and old laboratory animals.

15 Dec 2010

cFLIP protein makes breast cancer cells resistant to TRAIL-induced apoptosis

Researchers at the Andalusian Institute for Molecular Biology and Regenerative Medicine and the University of Granada found that cFLIP -an inhibitor of death ligand-induced apoptosis- is not only essential in breast tumor cells resistance to TRAIL treatments (a death ligand with a potent therapeutic potential against cancer), but this protein is also key to the survival of such cancer cells.

14 Dec 2010

Watson files generic Exalgo ANDA, confirms patent challenge from Mallinckrodt

Watson Pharmaceuticals, Inc. today confirmed that its subsidiary, Watson Laboratories, Inc. – Florida, filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market Hydromorphone Hydrochloride Extended-release Tablets, 8 mg, 12 mg, and 16 mg.

14 Dec 2010

Study links large waistline to increased risk of heart problems and type 2 diabetes

Researchers at Eastern Virginia Medical School’s Strelitz Diabetes Center and the school’s department of physiological sciences have published research showing a strong link between a large waistline and increased risk of Type 2 diabetes and cardiovascular disease.

14 Dec 2010

Poverty and obesity links

According to U.S. government researchers in a new report, women who are poor are much more likely to be obese but men are not. They revealed this Tuesday that where income does not greatly affect whether a man is obese, education affects both sexes. The team at the National Center for Health Statistics writes, “Among men, obesity prevalence is generally similar at all income levels, with a tendency to be slightly higher at higher income levels.”

14 Dec 2010

ISTA commences bepotastine besilate nasal spray Phase 2 study in seasonal allergic rhinitis

ISTA Pharmaceuticals, Inc., today announced it has initiated a Phase 2 clinical study of bepotastine besilate nasal spray for the treatment of symptoms associated with seasonal allergic rhinitis, the inflammation of the nasal passages caused by allergies. The randomized, placebo-controlled, parallel-group environmental study will evaluate the safety and efficacy of bepotastine besilate, dosed twice daily, in patients presenting with allergic rhinitis caused by one of the most potent seasonal allergy triggers, Mountain Cedar pollen.

14 Dec 2010

Tolerx commences TRX518 Phase 1 trial in malignant melanoma

Tolerx, Inc., a biopharmaceutical company developing novel therapies to treat autoimmune diseases and cancer by modulating T cell activity, today announced that it has initiated a Phase 1 clinical trial to assess the safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of TRX518, a monoclonal antibody designed to enhance the immune system by enabling T cells to more effectively attack cancer cells.

14 Dec 2010

Institute for Child and Family Health recognized for exemplary implementation of evidence-based interventions

Institute for Child and Family Health (ICFH), a non-profit organization that offers prevention and treatment programs for children and families in Miami-Dade County, today announced it has received the prestigious SAMHSA 2010 Science and Service Awards. This award recognizes exemplary implementation of evidence-based interventions that have been shown to prevent and/or treat mental illnesses and substance abuse.

14 Dec 2010

Medical Condition News

Inhaled corticosteroids may cause diabetes

Genes predict survival time, potential new treatments for patients with non-small cell lung cancer

Hemispherx granted extension to modify Ampligen NDA for CFS indication

Study shows breast inflammation promotes development and progression of cancer

BUSM awarded NCI EDRN, DOD grants to develop novel procedures for early detection of lung cancer

DBS targets same class of neuronal cells that respond to physical exercise and drug Prozac

New research reports more than 10% of RA patients lack health literacy

DARA's KRN5500 reduces allodynia in Phase 2a study for neuropathic pain in cancer patients

Davita launches online tool for dialysis patients

UCSF scientists explain why oligodendroglioma is more responsive to therapy than other brain tumors

Abbott initiates ABT-806 Phase 1 trial in EGFR expressing tumors

Neuropeptide S protein boosts memory

Study: HUCBs boost survival and maturation of hippocampal neurons

cFLIP protein makes breast cancer cells resistant to TRAIL-induced apoptosis

Watson files generic Exalgo ANDA, confirms patent challenge from Mallinckrodt

Study links large waistline to increased risk of heart problems and type 2 diabetes

Poverty and obesity links

ISTA commences bepotastine besilate nasal spray Phase 2 study in seasonal allergic rhinitis

Tolerx commences TRX518 Phase 1 trial in malignant melanoma

Institute for Child and Family Health recognized for exemplary implementation of evidence-based interventions

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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