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Mortality is higher in for-profit than non-profit dialysis centers, says study

If you need dialysis for advanced kidney disease, where you get it could make a big difference. A large study found that patients in certain large chain facilities are significantly more likely to die than those treated elsewhere. Mortality was also higher in for-profit than non-profit dialysis centers.

9 Dec 2010

Sunovion reports results of Latuda third phase 3 worldwide clinical trial for schizophrenia

Sunovion Pharmaceuticals Inc. today announced the results of the PEARL 3 study, the third phase 3 worldwide clinical trial of Latuda® (lurasidone HCl) tablets, a once-daily atypical antipsychotic agent recently approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with schizophrenia. In this six-week, placebo-controlled trial, both fixed doses of LATUDA 80 and 160 mg once-daily, demonstrated statistically significant improvement in symptoms of schizophrenia versus placebo across both primary and secondary efficacy measures.

9 Dec 2010

Laparoscopic approach still best for most patients, not for all: Study

If skin is the body's fortress against germ invaders, shouldn't minimally invasive surgeries - operations guided by camera probes, conducted entirely within the abdomen - carry less risk for serious infection than procedures that slice the same cavity wide open?

9 Dec 2010

EULAR welcomes EPSCO Council's decision on tackling chronic diseases in Europe

The European League Against Rheumatism welcomes the outcomes of yesterday's Council of the European Union. In its meeting on 7 December, ministers for health adopted Council Conclusions on chronic diseases, in which the Council calls on Member States and the European Commission to adopt concrete, coordinated measures to tackle chronic diseases in Europe.

9 Dec 2010

Study demonstrates new test for early diagnosis of Turner syndrome

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) has demonstrated a novel and accurate test for early diagnosis of Turner syndrome. Turner syndrome affects one in 1,500 to 2,000 female live births and early diagnosis allows for the timely management of short stature and co-morbid conditions including cardiac and renal problems.

9 Dec 2010

Researchers to study effect of resveratrol on impaired IGT in older prediabetic patients

Researchers at Albert Einstein College of Medicine of Yeshiva University have been awarded $600,000 from the American Diabetes Association to study the effect of resveratrol, a chemical compound most notably found in red wine and grapes, on impaired glucose tolerance in older adults.

9 Dec 2010

Phase 2 study data of ALD518 demonstrates reversal of anemia in NSCLC patients

Alder Biopharmaceuticals Inc. today announced that data from a Phase 2 study of its ALD518 investigational antibody therapeutic that targets interleukin-6 (IL-6) demonstrate a reversal of anemia in patients with advanced non-small cell lung cancer.

9 Dec 2010

Novel treatment strategy for social impairment of people with ASD

Eastern Virginia Medical School researchers have identified a potential novel treatment strategy for the social impairment of people with Autism Spectrum Disorders (ASD), an aspect of the condition that has a profound impact on quality of life.

9 Dec 2010

Winners of 2010 Quality and Innovation Awards announced

The Cancer Quality Council of Ontario, Cancer Care Ontario, and the Ontario Division of the Canadian Cancer Society today announced the winners of the 2010 Quality and Innovation Awards.

9 Dec 2010

Downstream cancer care linked to complications during surgery

Patients who have complications after colorectal cancer surgery are less likely to get chemotherapy, even when it is clearly recommended for their diagnosis, a new study from the University of Michigan Comprehensive Cancer Center finds.

9 Dec 2010

Weightlifting program does not increase risk of lymphedema in breast cancer survivors

A slowly progressive weight lifting program for breast cancer survivors did not increase their risk of lymphedema (arm swelling and discomfort), according to a study that will appear in the December 22/29 issue of JAMA. The study is being released early online to coincide with its presentation at the San Antonio Breast Cancer Symposium.

9 Dec 2010

Research into hospital bed technology could soon represent giant leap forward in patient care

A University of New Hampshire professor's research into hospital bed technology could soon represent a giant leap forward in patient care.

9 Dec 2010

Enbrel outperforms Humira in treating newly diagnosed RA patients: Report

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Amgen/Pfizer's Enbrel is the leading tumor necrosis factor -alpha inhibitor prescribed in newly diagnosed rheumatoid arthritis patients, outpacing Abbott's Humira in the first three lines of treatment.

9 Dec 2010

Teva, Active Biotech report positive initial results from laquinimod Phase III study in multiple sclerosis

Teva Pharmaceutical Industries Ltd. and Active Biotech announced today initial results from the two-year Phase III ALLEGRO study, which demonstrated that relapsing-remitting multiple sclerosis (MS) patients treated with 0.6 mg daily oral laquinimod experienced a statistically significant reduction in annualized relapse rate compared to placebo. Additional clinical endpoints, including significant reduction in disability progression, as measured by Expanded Disability Severity Scale (EDSS), were also achieved.

9 Dec 2010

Research findings could lead to new therapies to correct neurological disorders

Yale University researchers have found that a single molecule not only connects brain cells but also changes how we learn. The findings, reported in the December 9 issue of the journal Neuron, may help researchers discover ways to improve memory and could lead to new therapies to correct neurological disorders.

9 Dec 2010

Nottingham researchers develop new 'score' to detect heart disease in younger people

Experts at The University of Nottingham have developed a new 'score' to help GPs detect heart disease in younger people - before it damages their health.

9 Dec 2010

Researchers find weak association between parent-child dietary intake

As primary caregivers, parents are often believed to have a strong influence on children's eating behaviors. However, previous findings on parent-child resemblance in dietary intakes are mixed. Researchers from the Johns Hopkins Bloomberg School of Public Health reviewed and assessed the degree of association and similarity between children's and their parents' dietary intake based on worldwide studies published since 1980. The meta-analysis is featured in the December issue of the Journal of Epidemiology and Community Health.

9 Dec 2010

p53 activation offers a novel strategy for cancer therapy

A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53.

9 Dec 2010

Exergen's TemporalScanner demonstrates accuracy in temperature assessment for surgical patients

Temperatures taken orally or by temporal artery thermometry "are an accurate means of temperature assessment for adult patients undergoing colorectal or gynecology surgery," according to analysis published by the Journal of PeriAnesthesia Nursing. Accurate temperature readings are necessary to determine when to intervene for patients at all stages of their hospitalizations but especially during and immediately after surgical procedures to avoid post-operative complications.

9 Dec 2010

New objective criteria for evaluating hemostatic efficacy in treatment of VWD

Octapharma USA researchers presented new stringent, objective criteria used in the evaluation of hemostatic efficacy in the treatment of von Willebrand disease and reported on their application of these criteria in clinical trials during the recently completed National Hemophilia Foundation Annual Meeting.

9 Dec 2010