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Four caged xanthones can inhibit growth of CCA cell lines: Research article

Cholangiocarcinoma is a malignant tumor, characterized by a poor prognosis and unresponsive to conventional chemotherapeutic agents. Therefore, searching for novel and effective therapeutic agents for CCA is necessary. In previous studies, several caged xanthones from G. hanburyi have been reported to be potent antiproliferatives as well as having anticancer and anti-tumor activities and they induce apoptosis in various cancer cell lines.

13 May 2010

Study compares outcome of popular esophageal stents in patients with dysphagia

Less than 50% of patients with esophageal carcinoma are suitable for surgery at the time of diagnosis. Most of these patients present with locally advanced or metastatic disease and/or significant comorbidities. In such circumstances, the only therapeutic option is palliative care to treat dysphagia and prevent respiratory complications secondary to aspiration. Self-expanding metal stents have been proven effective for palliation of dysphagia in patients with esophageal carcinoma, tracheo-esophageal fistulas or anastomotic leaks.

13 May 2010

Individual's lifestyle choices can affect cholesterol, triglycerides levels: Mayo Clinic Health Letter

Diet and lifestyle choices aren't only evident on the bathroom scale. The effect of these choices is also reflected with relative accuracy in cholesterol numbers.

13 May 2010

Additional benefits of LAIAs over long-acting human insulin not been proven

It has so far not been proven that the long-acting insulin analogues (LAIAs) insulin detemir (trade name: Levemir) and insulin glargine (trade name: Lantus), which are approved for the treatment of type 1 diabetes, offer patients an additional benefit versus long-acting human insulin. This applies to adults as well as to children and adolescents. This is the result of the final report published by the Institute for Quality and Efficiency in Health Care (IQWiG) on 19 April 2010.

13 May 2010

Study: Treating serious gum disease in diabetics can help lower blood sugar levels

Researchers have found that reducing inflammation of the gums in people with diabetes can help lower the risk of serious complications associated with the condition, such as eye problems and heart disease.

13 May 2010

New Melody Transcatheter Pulmonary valve helps congenital heart defect patients avoid multiple surgeries

Congenital heart defects are the most common type of major birth defect in the U.S., affecting about 25,000 babies each year. Now, a new valve being used at the University of Michigan's C.S. Mott Children's Hospital Congenital Heart Center can help patients delay or avoid multiple surgeries.

13 May 2010

Seriously mentally ill are three times more likely to be imprisoned than hospitalized, report finds

USA Today: "On average, a seriously mentally ill person in the USA is three times more likely to be incarcerated than hospitalized, a report concludes today. In no state was a seriously mentally ill person — someone with schizophrenia or bipolar disorder, for example — less likely to be incarcerated than hospitalized, the report by the National Sheriffs' Association and the Treatment Advocacy Center found.

13 May 2010

NARSAD honours UNC's Patrick Sullivan with 2010 Distinguished Investigator Award

Patrick Sullivan, MD has received a 2010 Distinguished Investigator Award from NARSAD for a comparison of genetics in schizophrenia and bipolar disorder.

13 May 2010

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Researchers studying the common genetic disorder chromosome 22q.11 deletion syndrome have identified key proteins that act together to regulate early embryonic development. One protein is essential to life; in animal studies, embryos without the protein do not survive past the first few days of gestation.

13 May 2010

Atherotech to showcase VAP Cholesterol Test at NLA Scientific Sessions 2010

Atherotech Inc. will exhibit its VAP® Cholesterol Test in booth #102 at the National Lipid Association (NLA) Scientific Sessions 2010. The meeting takes place May 13-16 at the Sheraton Hotel and Towers in Chicago.

13 May 2010

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Regeneron Pharmaceuticals, Inc. (REGN) provided an update on two antibody product candidates in its pipeline and scheduled its first Investor Day to be held in New York City on July 15, 2010. Both product candidates, REGN727 (SAR236553) and, REGN475 (SAR164877) are being developed with sanofi-aventis under a global, strategic collaboration to discover, develop, and commercialize fully human antibodies.

13 May 2010

FDA warns of side effects from swallowing Benadryl Extra Strength Itch Stopping Gel

The U.S. Food and Drug Administration is warning consumers about potentially serious side effects from mistakenly swallowing Benadryl Extra Strength Itch Stopping Gel, an over-the-counter (OTC) product that should only be used on the skin.

13 May 2010

Melanoma is becoming increasingly common: Mayo Clinic Women's HealthSource

Melanoma -- the most serious form of skin cancer -- is becoming increasingly common, according to the May issue of Mayo Clinic Women's HealthSource.

13 May 2010

Report describes imaging features of superior mesenteric artery aneurysm

A recent case report published on May 14, 2010 in World Journal of Gastroenterology describes the imaging features of a ruptured superior mesenteric artery aneurysm,which created a giant hematoma and mimicked a pancreatic mass, with mild dilatation of main pancreatic duct.

13 May 2010

New case report addresses diagnostic significance of CT and MRI for DCF

Duodenocaval fistula is an uncommon but lethal clinical entity. The high mortality has been attributed to the difficulty of diagnosis before attempts at definitive therapy.

13 May 2010

Computerized systems can detect early eye problems related to diabetes: UI team

People with diabetes have an increased risk of blindness, yet nearly half of the approximately 23 million Americans with diabetes do not get an annual eye exam to detect possible problems.

13 May 2010

Resverlogix' Phase 2 ASSERT trial dosing complete ahead of schedule

Resverlogix is pleased to announce that the Phase 2 ASSERT clinical trial for its lead drug, RVX-208, a small molecule therapy for the treatment of atherosclerosis has now completed dosing. "The completion of dosing for our Phase 2 ASSERT trial, five months ahead of schedule and without any alterations to the dose levels of the three drug receiving cohorts, is another major step forward in the development of this important cardiovascular drug.

13 May 2010

Mayo Clinic Women's HealthSource offers information about abdominal aortic aneurysms

Abdominal aortic aneurysms have been considered mainly a man's problem. Men, more often than women, develop a weakened and bulging area in the aorta, the body's largest artery, which poses a risk of rupture. But according to the May issue of Mayo Clinic Women's HealthSource, women aren't risk free.

13 May 2010

Study evaluates cost-utility of MARS treatment in ALF patients

Numerous studies have documented the favorable effects of MARS albumin dialysis treatment on clinical and laboratory parameters and survival in liver failure patients. However, to ensure that limited resources are utilized in an ethical manner, the subjective feelings of the patient in terms of health-related quality of life and costs should also be taken into account.

13 May 2010

FDA approves Sagent's bacitracin for pneumonia and empyema

Sagent Pharmaceuticals, Inc., a privately held specialty pharmaceutical company, today announced FDA approval of bacitracin for injection, USP (bacitracin), an anti-infective product used to treat pneumonia and empyema. Bacitracin will be offered in a 50,000 MU, AP-rated, preservative-free, latex-free, single-dose vial packaged both individually and in packages of ten.

13 May 2010

Medical Condition News

Four caged xanthones can inhibit growth of CCA cell lines: Research article

Study compares outcome of popular esophageal stents in patients with dysphagia

Individual's lifestyle choices can affect cholesterol, triglycerides levels: Mayo Clinic Health Letter

Additional benefits of LAIAs over long-acting human insulin not been proven

Study: Treating serious gum disease in diabetics can help lower blood sugar levels

New Melody Transcatheter Pulmonary valve helps congenital heart defect patients avoid multiple surgeries

Seriously mentally ill are three times more likely to be imprisoned than hospitalized, report finds

NARSAD honours UNC's Patrick Sullivan with 2010 Distinguished Investigator Award

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Atherotech to showcase VAP Cholesterol Test at NLA Scientific Sessions 2010

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

FDA warns of side effects from swallowing Benadryl Extra Strength Itch Stopping Gel

Melanoma is becoming increasingly common: Mayo Clinic Women's HealthSource

Report describes imaging features of superior mesenteric artery aneurysm

New case report addresses diagnostic significance of CT and MRI for DCF

Computerized systems can detect early eye problems related to diabetes: UI team

Resverlogix' Phase 2 ASSERT trial dosing complete ahead of schedule

Mayo Clinic Women's HealthSource offers information about abdominal aortic aneurysms

Study evaluates cost-utility of MARS treatment in ALF patients

FDA approves Sagent's bacitracin for pneumonia and empyema

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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