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Deactivation of CRTC1 protein increases lifespan

Substantial evidence suggests that lifespan is increased if an organism restricts its daily calorie intake, a spartan regime that some say works by just making life seem longer. A team of scientists from the Salk Institute of Biological Studies has discovered a molecular switch flipped by hunger that could not only make longevity more appetizing but identify drug targets for patients with aging-related diseases such as type II diabetes or cancer.

17 Feb 2011

Single donor gifts lungs for two lung transplants

The University of Michigan Transplant Center celebrated a milestone recently, performing its 500th lung transplant. But there's much more to this story than a number.

17 Feb 2011

Loss of 'twenty-four' gene makes it harder to wake up

Northwestern University scientists have discovered a new mechanism in the core gears of the circadian clock. They found the loss of a certain gene, dubbed "twenty-four," messes up the rhythm of the common fruit fly's sleep-wake cycle, making it harder for the flies to awaken.

17 Feb 2011

New research shows high functionality after knee replacement even after two decades

Most patients who undergo total knee replacement are age 60 to 80. More than 90 percent of these individuals experience a dramatic reduction in knee pain and a significant improvement in the ability to perform common activities. However questions have been raised about the decline in physical function over the long term despite the absence of implant-related problems.

17 Feb 2011

New computer application automatically detects subtle epileptic brain lesions in MRI scans

Researchers from the Department of Neurology at NYU Langone Medical Center identified potential benefits of a new computer application that automatically detects subtle brain lesions in MRI scans in patients with epilepsy. In a study published in the February 2011 issue of PLoS ONE, the authors discuss the software's potential to assist radiologists in better identifying and locating visually undetectable, operable lesions.

17 Feb 2011

New study: Latino siblings of children with disability may face risk of negative outcomes

Latino siblings of children developmental disabilities such as Down syndrome and autism may face their own challenges, including anxiety and lower school performance, according to a new study led by researchers with the Bradley Hasbro Children's Research Center.

17 Feb 2011

Muscle, aptly enough, is born of cellular bullying, and not mutual consent

In fact, according to new research from Johns Hopkins, the fusion of muscle cells is a power struggle that involves a smaller mobile antagonist that points at, pokes and finally pushes into its larger, stationary partner using a newly identified finger-like projection.

17 Feb 2011

Study: BP oil spill causes psychological impact on people living in coastal communities

The explosion and fire on a BP-licensed oil platform in the Gulf of Mexico in April 2010 had huge environmental and economic effects, with millions of gallons of oil leaking into the water for more than five months. It also had significant psychological impact on people living in coastal communities, even in those areas that did not have direct oil exposure, according to researchers at the University of Maryland School of Medicine who worked in collaboration with the University of Florida, Gainesville.

17 Feb 2011

Over and under treatment of hyperglycemia in hospitalized patients leads to patient safety issues

The publication of the systematic review of intensive insulin therapy in hospitalized patients and the American College of Physicians (ACP) clinical guidelines for inpatient glucose control in the February 15th issue of Annals of Internal Medicine has again raised the issue of optimal management of hyperglycemia in the hospital.

17 Feb 2011

FDA, Threshold enter agreement on SPA for TH-302 Phase 3 trial in patients with soft tissue sarcoma

Threshold Pharmaceuticals, Inc. today announced that the Company reached agreement with the U.S. Food and Drug Administration on a Special Protocol Assessment for a Phase 3 randomized trial of TH-302 in patients with soft tissue sarcoma.

17 Feb 2011

Study: Simultaneous knee replacement linked with higher risk of adverse cardiovascular outcomes within 30 days

Replacing both knees in one surgery, or simultaneous total knee replacement was associated with significantly fewer prosthetic joint infections as well as other revision knee operations within one year after surgery, compared with total knee replacements performed in two separate procedures.

17 Feb 2011

Medtronic: Kyphon Balloon Kyphoplasty provides better back pain relief in cancer patients

Medtronic Inc., today announced the results of the first randomized, controlled trial comparing Kyphon Balloon Kyphoplasty with non-surgical care in treating spinal fractures in cancer patients. The study found that Kyphon Balloon Kyphoplasty provided cancer patients better back-specific function, more rapid back pain relief and improved quality of life compared with non-surgical care one month after treatment.

17 Feb 2011

New method may eliminate colonoscopies

Nobody enjoys colonoscopies, including mice. University of Missouri researchers are excited about the potential of using genetic biomarkers to predict colon cancer caused by inflammation. A new method developed at the MU Research Animal Diagnostic Laboratory (RADIL) could eventually lead to a method that might eliminate colonoscopies altogether.

17 Feb 2011

Study sheds light on novel functions of certain PCSK enzymes

Recent studies conducted at the Institut de recherches cliniques de Montr-al on a group of PCSK enzymes could have a positive impact on health, from cholesterol to osteoporosis.

17 Feb 2011

Amicus to present additional positive data from Amigal Phase 2 extension study for Fabry disease

Amicus Therapeutics today announced that additional positive data from the ongoing Phase 2 extension study of its investigational drug Amigal™ (migalastat HCl) for Fabry disease will be presented at the Lysosomal Disease Network WORLD Symposium in Las Vegas, Nevada, February 16-18th, 2011.

17 Feb 2011

Patients with high blood pressure can benefit from 'adherence therapy' course

A high proportion of patients with high blood pressure are failing to take their medication properly and would benefit clinically from a course of 'adherence therapy', according to new research from the University of East Anglia.

17 Feb 2011

U.S. Patent Office issues Notice of Allowance to Biomoda's CyPath assay for cancer detection

Cancer diagnostics company Biomoda, Inc. received Notice of Allowance for a U.S. Patent application on a quantitative method for scoring cells labeled with the CyPath assay to determine whether cells are dysplastic or carcinomic by measuring the photon emission rate.

17 Feb 2011

Sonablate HIFU device is now available in Brazil to treat prostate cancer

USHIFU LLC, a world leader in minimally invasive high intensity focused ultrasound technologies and manufacturer of the Sonablate 500 medical device, announces that HIFU with the Sonablate is available to prostate cancer patients for the first time in Brazil at Hospital Nossa Senhora das Gracas in Curitiba, capital city of the state of Parana in southern Brazil.

17 Feb 2011

Oncolytics begins enrollment in 2-Arm carboplatin Phase II randomized study for pancreatic cancer

Oncolytics Biotech Inc. announced today that enrollment has begun in a 2-Arm randomized Phase II study of carboplatin, paclitaxel plus REOLYSIN versus carboplatin and paclitaxel alone in the first line treatment of patients with recurrent or metastatic pancreatic cancer.

17 Feb 2011

Impaired brain insulin action may worsen type 2 diabetes

Researchers from Mount Sinai School of Medicine have discovered a novel function of brain insulin, indicating that impaired brain insulin action may be the cause of the unrestrained lipolysis that initiates and worsens type 2 diabetes in humans. The research is published this month in the journal Cell Metabolism.

17 Feb 2011

Medical Condition News

Deactivation of CRTC1 protein increases lifespan

Single donor gifts lungs for two lung transplants

Loss of 'twenty-four' gene makes it harder to wake up

New research shows high functionality after knee replacement even after two decades

New computer application automatically detects subtle epileptic brain lesions in MRI scans

New study: Latino siblings of children with disability may face risk of negative outcomes

Muscle, aptly enough, is born of cellular bullying, and not mutual consent

Study: BP oil spill causes psychological impact on people living in coastal communities

Over and under treatment of hyperglycemia in hospitalized patients leads to patient safety issues

FDA, Threshold enter agreement on SPA for TH-302 Phase 3 trial in patients with soft tissue sarcoma

Study: Simultaneous knee replacement linked with higher risk of adverse cardiovascular outcomes within 30 days

Medtronic: Kyphon Balloon Kyphoplasty provides better back pain relief in cancer patients

New method may eliminate colonoscopies

Study sheds light on novel functions of certain PCSK enzymes

Amicus to present additional positive data from Amigal Phase 2 extension study for Fabry disease

Patients with high blood pressure can benefit from 'adherence therapy' course

U.S. Patent Office issues Notice of Allowance to Biomoda's CyPath assay for cancer detection

Sonablate HIFU device is now available in Brazil to treat prostate cancer

Oncolytics begins enrollment in 2-Arm carboplatin Phase II randomized study for pancreatic cancer

Impaired brain insulin action may worsen type 2 diabetes

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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