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Alternative anti-inflammatory approach to epilepsy management

If common anticonvulsant drugs fail to manage epileptic seizures, then perhaps the anti-inflammatory route is the way to go. That's according to Mattia Maroso and colleagues from the Mario Negri Institute for Pharmacological Research in Milan, Italy, who found that giving mice repeated doses of a specific enzyme inhibitor significantly reduced both chronic epileptic activity and acute seizures.

28 Mar 2011

ADDF awards Yuma $249,810 grant for Alzheimer's research

The Alzheimer's Drug Discovery Foundation announced today that it has awarded a grant of $249,810 to Yuma Therapeutics Corporation to develop small molecules to treat Alzheimer's disease.

28 Mar 2011

ActiveSite's ASP-440 plasma kallikrein inhibitor effective in reducing diabetes-induced blood-retinal barrier breakdown

ActiveSite Pharmaceuticals, Inc., announced today the online publication of a study in the journal Diabetes that describes the effectiveness of its novel plasma kallikrein inhibitor ASP-440 in reducing blood-retinal barrier breakdown in a rodent model of diabetes.

28 Mar 2011

Ascension launches TITAN Modular Shoulder Fracture Prosthesis

Ascension Orthopedics, Inc., a world leader in PyroCarbon orthopedic devices, announces the market release of the TITAN Modular Shoulder Fracture Prosthesis. The TITAN Modular Total Shoulder System now provides a unique way to address difficult fracture procedures. The system's modularity allows the surgeon to fit patient anatomy by independently adjusting the height of the modular body and stem without need for jigs or use of cement.

28 Mar 2011

CRANE ChemPharma to launch Saunders PV Life Science Diaphragm and S360 Actuator at INTERPHEX 2011

CRANE ChemPharma Flow Solutions is pleased to introduce two new products from its Saunders brand during INTERPHEX 2011.

28 Mar 2011

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

Everist Genomics today announced the worldwide commercial availability of its OncoDefender-CRC colorectal cancer assay, the first and only molecular prognostic test capable of accurately predicting the risk of recurrence of cancer in patients previously treated with surgical resection of a Stage I/II colon cancer tumor or Stage I rectal cancer tumor.

28 Mar 2011

Dosing commences in Phase I clinical study of GenSpera's G-202 at Cancer Therapy & Research Center

GenSpera, Inc. announced that the first patient was dosed in the ongoing Phase I clinical study of its chemotherapeutic agent, G-202, at the Cancer Therapy & Research Center (CTRC) at The University of Texas Health Science Center at San Antonio in San Antonio, Texas.

28 Mar 2011

Pathway Medical initiates enrollment in JETSTREAM G3 Calcium Study in peripheral artery disease

Pathway Medical Technologies, Inc., an innovator of endovascular treatments for peripheral vascular disease (PVD), today announced enrollment of the first patient in the company's JETSTREAM G3 Calcium Study, a prospective, single-arm, multi-center registry to evaluate the treatment effects of the JETSTREAM G3 System in patients with moderate to severely calcified peripheral artery disease.

28 Mar 2011

Phase 2a study of DARA BioSciences KRN5500 in treatment of cancer pain reaches primary end-point

Researchers studying a new medication for neuropathic pain have reported intriguing findings about placebo response versus drug response from a Phase 2a proof-of-concept study. They presented their findings in a poster session at the 2011 International Conference on Accelerating the Development of Enhanced Pain Treatments.

28 Mar 2011

Cancer drug Gleevec may hold promise against scleroderma: Study

A drug approved to treat certain types of cancer has shown promising results in the treatment of patients with scleroderma, according to results from an open-label Phase II trial. While the drug's efficacy must be demonstrated in a Phase III trial, the gold standard for testing a drug, researchers are optimistic that Gleevec- (imatinib) could potentially be a weapon against the chronic connective tissue disease for which a treatment has remained elusive.

28 Mar 2011

MolecularMD and ARIAD collaborate to develop and commercialize CML, ALL diagnostic test

ARIAD Pharmaceuticals, Inc. and MolecularMD Corporation today announced an exclusive collaboration agreement in which MolecularMD will develop and commercialize a companion diagnostic test to identify the T315I mutation of the BCR-ABL gene in patients with chronic myeloid leukemia and Philadelphia positive acute lymphoblastic leukemia.

28 Mar 2011

First open fetal surgery to treat lung malformations performed at Texas Children's Hospital

Experts from Texas Children's Fetal Center published a study that appears in volume 46, issue 2 of the Journal of Pediatric Surgery documenting the first successful cases of open fetal surgery to treat fetal lung malformations in the Southern U.S.

28 Mar 2011

AVEO to present tivozanib preclinical data, monoclonal antibody pipeline at AACR meeting

AVEO Pharmaceuticals, Inc. today announced that preclinical data on tivozanib, AVEO's lead product candidate designed to optimally block the VEGF pathway by inhibiting all three VEGF receptors, and the company's monoclonal antibody pipeline will be presented during poster sessions at the American Association for Cancer Research 102nd Annual Meeting 2011 being held April 2-6, 2011 in Orlando, Fla.

28 Mar 2011

Leicester professor receives Outstanding Alumni Achievement Award for Cardiovascular research

The winner of the University of Leicester inaugural Outstanding Alumni Achievement Award was revealed at the 2011 Alumni Black Tie Dinner on Thursday 17 February at the Mandarin Hotel in London.

28 Mar 2011

Drugs can prevent risk of breast cancer in women, experts say

Drugs could be used to prevent breast cancer in women at high risk of the disease in the same way that statins are used for heart disease if trials looking at ways of predicting risk are successful, according to an international panel of cancer experts.

28 Mar 2011

Toshiba introduces new Infinix-i cardiovascular X-ray systems

Accurately navigating and interpreting cardiovascular anatomy for precise device deployment is a challenge to physicians during complex interventional procedures. Providing physicians with greater confidence during these difficult procedures, Toshiba America Medical Systems, Inc. is introducing upgrades to its Infinix-i product line.

28 Mar 2011

NMSS grants Adeona's ongoing Trimesta trial with $409,426 to treat MS

Adeona Pharmaceuticals, Inc., a developer of innovative medicines for serious central nervous system diseases, announced today that the ongoing clinical trial of its Trimesta drug candidate has received an additional $409,426 in grant funding from the National Multiple Sclerosis Society.

28 Mar 2011

MRF: FDA's decision on Yervoy offers new treatment options for patients with melanoma

Thirteen years of waiting is now over for melanoma patients. That's how long it's been since the last therapy became available to treat the most lethal form of skin cancer – melanoma. The FDA today announced approval of Yervoy, an immunotherapy treatment for advanced melanoma.

28 Mar 2011

Research: Written action plan with prescriptions can improve asthma control in children

It sounds unbelievably simple but it's true - a written action plan for asthma treatment, attached to the drug prescription, improves asthma control in children. "Acute care visits for asthma often signal a management failure," said Dr. Francine Ducharme, of the University of Montreal's Department of Pediatrics and the Sainte-Justine University Hospital Centre.

28 Mar 2011

Essex scientists receive £205,000 grant for breast cancer research

Scientists from the University of Essex have received a £205,000 grant from Cancer Research UK to investigate the early reversible changes in the genes associated with breast cancer development.

28 Mar 2011

Medical Condition News

Alternative anti-inflammatory approach to epilepsy management

ADDF awards Yuma $249,810 grant for Alzheimer's research

ActiveSite's ASP-440 plasma kallikrein inhibitor effective in reducing diabetes-induced blood-retinal barrier breakdown

Ascension launches TITAN Modular Shoulder Fracture Prosthesis

CRANE ChemPharma to launch Saunders PV Life Science Diaphragm and S360 Actuator at INTERPHEX 2011

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

Dosing commences in Phase I clinical study of GenSpera's G-202 at Cancer Therapy & Research Center

Pathway Medical initiates enrollment in JETSTREAM G3 Calcium Study in peripheral artery disease

Phase 2a study of DARA BioSciences KRN5500 in treatment of cancer pain reaches primary end-point

Cancer drug Gleevec may hold promise against scleroderma: Study

MolecularMD and ARIAD collaborate to develop and commercialize CML, ALL diagnostic test

First open fetal surgery to treat lung malformations performed at Texas Children's Hospital

AVEO to present tivozanib preclinical data, monoclonal antibody pipeline at AACR meeting

Leicester professor receives Outstanding Alumni Achievement Award for Cardiovascular research

Drugs can prevent risk of breast cancer in women, experts say

Toshiba introduces new Infinix-i cardiovascular X-ray systems

NMSS grants Adeona's ongoing Trimesta trial with $409,426 to treat MS

MRF: FDA's decision on Yervoy offers new treatment options for patients with melanoma

Research: Written action plan with prescriptions can improve asthma control in children

Essex scientists receive £205,000 grant for breast cancer research

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AI-powered analytics and experimental validation

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