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Combination therapy initially, best for blood pressure control: ACCELERATE study

A new study published online Jan. 13 in The Lancet shows that patients with high blood pressure respond better to a combination drug therapy than those on monotherapy. Also patients who undergo the two-drug treatment after taking the single-drug therapy also experience better blood pressure outcomes, though not at the same level as those who began with the combination treatment, according to research.

13 Jan 2011

Adjunctive lacosamide reduces seizures and improves responder rates

Comprehensive analyses of pooled data from three randomized, double-blind, placebo-controlled Phase II/III trials showing the efficacy and tolerability of Vimpat® (lacosamide) C-V for patients with partial-onset seizures, regardless of the type of concomitant AED used, have been published in the drug evaluation journal, CNS Drugs.

13 Jan 2011

Free concert to bring the magic of music to young people with autism and their families

The Help Group and Music for Autism are proud to present the first of a series of four autism-friendly interactive concerts designed for young people with autism and their families.

13 Jan 2011

BMJ publishes clinical study of noninvasive, plasma DNA-based approach for prenatally detecting Down's syndrome

Sequenom is very pleased to note the publication in the British Medical Journal of a groundbreaking international study led by our longstanding collaborator, Professor Dennis Lo of The Chinese University of Hong Kong.

13 Jan 2011

NEJM releases findings about behavioral impact of personal genetic testing

Navigenics, a leading personal genomics company, announced today that The New England Journal of Medicine has published findings from the Scripps Genomic Health Initiative, a research study sponsored by Scripps Translational Science Institute to assess the behavioral impact of personal genetic testing.

13 Jan 2011

Huge falloff in teens' recalled exposure to drug abuse prevention messages

The University of Michigan's Monitoring the Future study (MTF) – the largest survey on teen drug abuse tracking over 46,000 8th, 10th and 12th graders – found a huge falloff in teens' recalled exposure to drug abuse prevention messages over the past seven years. The new data from the MTF study have been released at a time when teens themselves report finding the drug-prevention messages to be effective.

13 Jan 2011

Video submissions invited for the 2011 Neuro Film Festival competition

People who have loved ones affected by a brain disorder or have been affected by a disorder themselves still have the opportunity to share their story by submitting a short video to the 2011 Neuro Film Festival(SM) competition at http://www.neurofilmfestival.com. The deadline for entries is February 15, 2011.

13 Jan 2011

Exposure to room light prior to bedtime suppresses melatonin levels, increases cancer and diabetes risk: Study

According to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism, exposure to electrical light between dusk and bedtime strongly suppresses melatonin levels and may impact physiologic processes regulated by melatonin signaling, such as sleepiness, thermoregulation, blood pressure and glucose homeostasis.

13 Jan 2011

Epigenomics concludes feasibility phase in development of improved product concept for Epi proColon

Epigenomics AG, the cancer molecular diagnostic company, today announced that it has concluded the feasibility phase in the development of an improved product concept for Epi proColon, the Company's DNA methylation-based blood test for assistance in the detection of individuals with colorectal cancer.

13 Jan 2011

Study: Women with abnormal mammograms experience lower QoL and increased anxiety

Doctors are calling for women to receive more information about the pitfalls of breast cancer screening, as well as the benefits, after some women who received false-positive results faced serious anxiety and reduced quality of life for at least a year.

13 Jan 2011

Interventions for preventing falls in older persons should include an exercise component

In the first update of the American Geriatrics Society and the British Geriatric Society's guidelines on preventing falls in older persons since 2001, they now recommend that all interventions for preventing falls should include an exercise component and that a number of new assessments should be used, including; feet and footwear, fear of falling, and ability to carry out daily living activities.

13 Jan 2011

Genetic information from Guthrie cards may serve as valuable resource to diagnose infant diseases

Van Andel Research Institute researchers have developed a method that can yield more information from archived newborn blood that has implications for a vast array of research, including population health studies and answering questions about diseases in infants and children.

13 Jan 2011

Study supports use of PRX as an anti-cataract agent

Scientists are reporting a scientific basis for the long-standing belief that a widely used non-prescription drug in China and certain other countries can prevent and treat cataracts, a clouding of the lens of the eye that is a leading cause of vision loss worldwide. Their study appears in Inorganic Chemistry, an ACS journal.

13 Jan 2011

Brain cell destroying genetic mechanism responsible for development of AD

Researchers at the University of British Columbia and Vancouver Coastal Health Research Institute have discovered that the genetic mechanism which destroys brain cells is responsible for early development of Alzheimer's Disease in people with Down Syndrome and for development of Alzheimer's Disease in general population - providing a potential new target for drugs that could forestall dementia in people with either condition.

13 Jan 2011

BP-lowering medications provide long-term benefit of reducing death risk from cardiovascular disease

In a study published in December 2010, in Hypertension, a journal of the American Heart Association, investigators have shown that early treatment with blood pressure-lowering medications provides a long-term benefit of reducing the risk of death from cardiovascular disease.

13 Jan 2011

SRI International receives $17.4 million grant to boost treatments for cardiovascular, lung, blood diseases

SRI International, an independent nonprofit research and development organization, announced today that it has been awarded two preclinical services contracts totaling $17.4 million by the National Heart, Lung, and Blood Institute, one of the National Institutes of Health.

13 Jan 2011

Transition of oncology programme into lead optimisation triggers EUR 2.0M milestone payment to Evotec

Evotec AG today announced that its research alliance with Boehringer Ingelheim has reached a milestone triggering a payment of EUR 2.0 million to Evotec.

13 Jan 2011

7,8-Dihydroxyflavone holds potential for treatment of fear based disorders

Living a traumatic experience favours the persistence of fear associated with an aversive stimulus, known as fear conditioning and such effect, in mice, can be suppressed with a single dosis of 7,8-Dihydroxyflavone, a type of flavonoid which boosts the ability to acquire new emotional learnings.

13 Jan 2011

Genomic research could help doctors better target oxaliplatin drug to treat colorectal cancer patients: Study

Genomic research could help doctors better target a drug widely used to treat colorectal cancer patients, according to a study by Genomic Health Inc. and the Translational Genomics Research Institute.

13 Jan 2011

Interaction with opposite sex activates specific genes

Scientists from Texas have made an important step toward understanding human mating behavior by showing that certain genes become activated in fruit flies when they interact with the opposite sex. This research, published in the January 2011 issue of the journal GENETICS, shows that courtship behaviors may be far more influenced by genetics than previously thought. In addition, understanding why and how these genes become activated within social contexts may also lead to insight into disorders such as autism.

13 Jan 2011

Medical Condition News

Combination therapy initially, best for blood pressure control: ACCELERATE study

Adjunctive lacosamide reduces seizures and improves responder rates

Free concert to bring the magic of music to young people with autism and their families

BMJ publishes clinical study of noninvasive, plasma DNA-based approach for prenatally detecting Down's syndrome

NEJM releases findings about behavioral impact of personal genetic testing

Huge falloff in teens' recalled exposure to drug abuse prevention messages

Video submissions invited for the 2011 Neuro Film Festival competition

Exposure to room light prior to bedtime suppresses melatonin levels, increases cancer and diabetes risk: Study

Epigenomics concludes feasibility phase in development of improved product concept for Epi proColon

Study: Women with abnormal mammograms experience lower QoL and increased anxiety

Interventions for preventing falls in older persons should include an exercise component

Genetic information from Guthrie cards may serve as valuable resource to diagnose infant diseases

Study supports use of PRX as an anti-cataract agent

Brain cell destroying genetic mechanism responsible for development of AD

BP-lowering medications provide long-term benefit of reducing death risk from cardiovascular disease

SRI International receives $17.4 million grant to boost treatments for cardiovascular, lung, blood diseases

Transition of oncology programme into lead optimisation triggers EUR 2.0M milestone payment to Evotec

7,8-Dihydroxyflavone holds potential for treatment of fear based disorders

Genomic research could help doctors better target oxaliplatin drug to treat colorectal cancer patients: Study

Interaction with opposite sex activates specific genes

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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